Search Results - "Chen, Ruiguo"
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Vascularized human cortical organoids (vOrganoids) model cortical development in vivo
Published in PLoS biology (01-05-2020)“…Modeling the processes of neuronal progenitor proliferation and differentiation to produce mature cortical neuron subtypes is essential for the study of human…”
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Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus
Published in Nature communications (13-08-2020)“…The neuroendocrine hypothalamus is the central regulator of vital physiological homeostasis and behavior. However, the cellular and molecular properties of…”
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3
Decoding the development of the human hippocampus
Published in Nature (London) (23-01-2020)“…The hippocampus is an important part of the limbic system in the human brain that has essential roles in spatial navigation and the consolidation of…”
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Role of Wdr45b in maintaining neural autophagy and cognitive function
Published in Autophagy (02-04-2020)“…Macroautophagy/autophagy functions as a quality control mechanism by degrading misfolded proteins and damaged organelles and plays an essential role in…”
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Biodegradable BBG/PCL composite scaffolds fabricated by selective laser sintering for directed regeneration of critical-sized bone defects
Published in Materials & design (01-01-2023)“…(a) Radius modeling of the rabbit model at different stages. (b) The schematic of the fabrication procedure for BBG/PCL rabbit radius scaffolds and their usage…”
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Rapid and Efficient Conversion of Human Fibroblasts into Functional Neurons by Small Molecules
Published in Stem cell reports (12-11-2019)“…Recent studies have demonstrated that human astrocytes and fibroblasts can be directly converted into functional neurons by small molecules. However,…”
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Single-cell transcriptome analysis reveals cell lineage specification in temporal-spatial patterns in human cortical development
Published in Science advances (01-08-2020)“…Neurogenesis processes differ in different areas of the cortex in many species, including humans. Here, we performed single-cell transcriptome profiling of the…”
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Clinical efficiency of simultaneous CNV-seq and whole-exome sequencing for testing fetal structural anomalies
Published in Journal of translational medicine (03-01-2022)“…Birth defects are responsible for approximately 7% of neonatal deaths worldwide by World Health Organization in 2004. Many methods have been utilized for…”
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Ferrodifferentiation regulates neurodevelopment via ROS generation
Published in Science China. Life sciences (01-08-2023)“…Iron is important for life, and iron deficiency impairs development, but whether the iron level regulates neural differentiation remains elusive. In this…”
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Whole exome sequencing is an alternative method in the diagnosis of mitochondrial DNA diseases
Published in Molecular genetics & genomic medicine (01-06-2022)“…Background Mitochondrial disease (MD) is genetically a heterogeneous group of disorders with impairment in respiratory chain complexes or pathways associated…”
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Titanium Nanobowl-Based Nest-Like Nanofiber Structure Prepared at Room Temperature and Pressure Promotes Osseointegration of Beagle Implants
Published in Frontiers in bioengineering and biotechnology (24-02-2022)“…Nest-like nanofiber structures have potential applications in surface modifications of titanium implants. In this study, nest-like nanofiber structures were…”
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Analysis of Magnetic Field Intensity and Induced Current under Live Working Based on Charge Simulation Method
Published in MATEC Web of Conferences (01-01-2015)“…To the problem that safety distance is insufficient for 500 kV substation live working, a magnetic field analysis method for overhead line bus is given based…”
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Journal Article Conference Proceeding -
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Design of a Shared-Aperture Co-Polarized Antenna With Minimal Mutual Coupling for Practical Integration in a Dual-Mode OAM Array
Published in IEEE transactions on circuits and systems. II, Express briefs (01-10-2024)“…This brief presents a co-linear polarized antenna array with low mutual coupling characteristics. The antenna element employs a hybrid feed strategy, combining…”
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Heat sensitive E-helix cut ferritin nanocages for facile and high-efficiency loading of doxorubicin
Published in International journal of biological macromolecules (31-12-2023)“…Ferritin possesses a stable and uniform cage structure, along with tumor-targeting properties and excellent biocompatibility, making it a promising drug…”
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Nanosized HCA-coated borate bioactive glass with improved wound healing effects on rodent model
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-12-2021)“…[Display omitted] •A simple approach to obtain nanosized and porous HCA-coated borate bioactive glass.•Nano-HCA@BG provides a better dressing for applications…”
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Magnetosome-inspired synthesis of soft ferrimagnetic nanoparticles for magnetic tumor targeting
Published in Proceedings of the National Academy of Sciences - PNAS (08-11-2022)“…Magnetic targeting is one of the most promising approaches for improving the targeting efficiency by which magnetic drug carriers are directed using external…”
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Boosting SARS-CoV‑2 Enrichment with Ultrasmall Immunomagnetic Beads Featuring Superior Magnetic Moment
Published in Analytical chemistry (Washington) (01-08-2023)“…The isolation and enrichment efficiency of SARS-CoV-2 virus in complex biological environments is often relatively low, presenting challenges in direct…”
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Novel Titanium Implant: A 3D Multifunction Architecture with Charge‐Trapping and Piezoelectric Self‐Stimulation
Published in Advanced healthcare materials (01-04-2023)“…Implant‐associated infection and inflammation are the main causes of implant failure, causing irreversible damage and significantly increasing clinical risks…”
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Morphological and Physiological Characteristics of Ebf2-EGFP-Expressing Cajal-Retzius Cells in Developing Mouse Neocortex
Published in Cerebral cortex (New York, N.Y. 1991) (14-08-2019)“…Cajal-Retzius (CR) cells are one of the earliest populations of neurons in the cerebral cortex of rodents and primates, and they play a critical role in…”
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Borate bioactive glass enhances 3D bioprinting precision and biocompatibility on a sodium alginate platform via Ca2+ controlled self-solidification
Published in International journal of biological macromolecules (01-10-2024)“…Sodium alginate (SA) has gained widespread acclaim as a carrier medium for three-dimensional (3D) bioprinting of cells and a diverse array of bioactive…”
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