Search Results - "Chen, Ruichuan"

Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II by Lu, Xiaodong, Zhu, Xinxing, Li, You, Liu, Min, Yu, Bin, Wang, Yu, Rao, Muhua, Yang, Haiyang, Zhou, Kai, Wang, Yao, Chen, Yanheng, Chen, Meihua, Zhuang, Songkuan, Chen, Lin-Feng, Liu, Runzhong, Chen, Ruichuan

“…The association of DSIF and NELF with initiated RNA Polymerase II (Pol II) is the general mechanism for inducing promoter-proximal pausing of Pol II. However,…”
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Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4 by Yang, Zhiyuan, Yik, Jasper H.N., Chen, Ruichuan, He, Nanhai, Jang, Moon Kyoo, Ozato, Keiko, Zhou, Qiang

“…The cyclinT1/Cdk9 heterodimer that constitutes core P-TEFb is generally presumed to be the transcriptionally active form for stimulating RNA polymerase II…”
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H. pylori infection confers resistance to apoptosis via Brd4-dependent BIRC3 eRNA synthesis by Chen, Yanheng, Sheppard, Donald, Dong, Xingchen, Hu, Xiangming, Chen, Meihua, Chen, Ruichuan, Chakrabarti, Jayati, Zavros, Yana, Peek, Richard M., Chen, Lin-Feng

“…H. pylori infection is one of the leading causes of gastric cancer and the pathogenicity of H. pylori infection is associated with its ability to induce…”
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Inhibition of P-TEFb (CDK9/Cyclin T) Kinase and RNA Polymerase II Transcription by the Coordinated Actions of HEXIM1 and 7SK snRNA by Yik, Jasper H.N, Chen, Ruichuan, Nishimura, Rieko, Jennings, Jennifer L, Link, Andrew J, Zhou, Qiang

“…The positive transcriptional elongation factor b (P-TEFb), consisting of CDK9 and cyclin T, stimulates transcription by phosphorylating RNA polymerase II. It…”
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Phosphorylated Positive Transcription Elongation Factor b (P-TEFb) Is Tagged for Inhibition through Association with 7SK snRNA by Chen, Ruichuan, Yang, Zhiyuan, Zhou, Qiang

“…The positive transcription elongation factor b (P-TEFb), comprising CDK9 and cyclin T, stimulates transcription of cellular and viral genes by phosphorylating…”
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Abnormal Response to the Anorexic Effect of GHS-R Inhibitors and Exenatide in Male Snord116 Deletion Mouse Model for Prader-Willi Syndrome by Lin, Dahe, Wang, Qi, Ran, Haiying, Liu, Kai, Wang, Yao, Wang, Juanjuan, Liu, Yazhen, Chen, Ruichuan, Sun, Yuxiang, Liu, Runzhong, Ding, Feng

“…Prader-Willi syndrome (PWS) is a genetic disease characterized by persistent hunger and hyperphagia. The lack of the Snord116 small nucleolar RNA cluster has…”
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A Human Immunodeficiency Virus Type 1 Tat-Like Arginine-Rich RNA-Binding Domain Is Essential for HEXIM1 To Inhibit RNA Polymerase II Transcription through 7SK snRNA-Mediated Inactivation of P-TEFb by Yik, Jasper H. N., Chen, Ruichuan, Pezda, Andrea C., Samford, Craig S., Zhou, Qiang

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Compensatory Contributions of HEXIM1 and HEXIM2 in Maintaining the Balance of Active and Inactive Positive Transcription Elongation Factor b Complexes for Control of Transcription by Yik, Jasper H.N., Chen, Ruichuan, Pezda, Andrea C., Zhou, Qiang

“…Human positive transcriptional elongation factor b (P-TEFb), consisting of a cyclin-dependent kinase 9-cyclin T heterodimer, stimulates general and…”
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A holistic immune system against active P2P worms by Eng Keong Lua, Ruichuan Chen

“…Active Peer-to-Peer (P2P) worms present serious threats to the global Internet by exploiting popular P2P applications to perform rapid topological…”
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Social Trust and Reputation in Online Social Networks by Eng Keong Lua, Ruichuan Chen, Zhuhua Cai

“…Online social networking systems are rapidly becoming popular on the Internet for users to share, organize and locate interesting content. However, these…”
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Bring order to online social networks by Ruichuan Chen, Eng Keong Lua, Zhuhua Cai

“…Online social networking systems are rapidly becoming popular for users to share, organize and locate interesting content. However, these systems have…”
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Will Serverless Computing Revolutionize NFV? by Aditya, Paarijaat, Akkus, Istemi Ekin, Beck, Andre, Chen, Ruichuan, Hilt, Volker, Rimac, Ivica, Satzke, Klaus, Stein, Manuel

“…Communication networks need to be both adaptive and scalable. The last few years have seen an explosive growth of software-defined networking (SDN) and network…”
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WebIBC: Identity Based Cryptography for Client Side Security in Web Applications by Zhi Guan, Zhen Cao, Xuan Zhao, Ruichuan Chen, Zhong Chen, Xianghao Nan

“…The growing popularity of web applications in the last few years has led users to give the management of their data to online application providers, which will…”
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Enabling scalable and adaptive machine learning training via serverless computing on public cloud by Ali, Ahsan, Ma, Xiaolong, Zawad, Syed, Aditya, Paarijaat, Akkus, Istemi Ekin, Chen, Ruichuan, Yang, Lei, Yan, Feng

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ApproxIoT: Approximate Analytics for Edge Computing by Wen, Zhenyu, Quoc, Do Le, Bhatotia, Pramod, Chen, Ruichuan, Lee, Myungjin

“…IoT-enabled devices continue to generate a massive amount of data. Transforming this continuously arriving raw data into timely insights is critical for many…”
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A Generic, High-Performance, Compression-Aware Framework for Data Parallel DNN Training by Wu, Hao, Wang, Shiyi, Bai, Youhui, Li, Cheng, Zhou, Quan, Yi, Jun, Yan, Feng, Chen, Ruichuan, Xu, Yinlong

“…Gradient compression is a promising approach to alleviating the communication bottleneck in data parallel deep neural network (DNN) training by significantly…”
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Gillis: Serving Large Neural Networks in Serverless Functions with Automatic Model Partitioning by Yu, Minchen, Jiang, Zhifeng, Ng, Hok Chun, Wang, Wei, Chen, Ruichuan, Li, Bo

“…The increased use of deep neural networks has stimulated the growing demand for cloud-based model serving platforms. Serverless computing offers a simplified…”
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capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP by Xue, Yuhua, Yang, Zhiyuan, Chen, Ruichuan, Zhou, Qiang

“…The 7SK snRNP represents a major reservoir of activity where P-TEFb, a general transcription factor key for RNA polymerase II elongation, can be withdrawn to…”
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BET Inhibition Attenuates Helicobacter pylori-Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation by Chen, Jinjing, Wang, Zhen, Hu, Xiangming, Chen, Ruichuan, Romero-Gallo, Judith, Peek, Jr, Richard M, Chen, Lin-Feng

“…Helicobacter pylori infection causes chronic gastritis and peptic ulceration. H. pylori-initiated chronic gastritis is characterized by enhanced expression of…”
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CaMKII: do not work too hard in the failing heart by Liu, Min, Li, You, Chen, Ruichuan

“…CaMKIIδ, a calcium/calmodulin‐dependent protein kinase, plays pivotal roles in the development of heart disease. In this issue of The Journal of Pathology,…”
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