Search Results - "Chen, Rishard"
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An Integrated In Vivo/In Vitro Protein Production Platform for Site-Specific Antibody Drug Conjugates
Published in Bioengineering (Basel) (28-02-2023)“…The XpressCF+ cell-free protein synthesis system is a robust platform for the production of non-natural amino acids containing antibodies, which enable the…”
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Factors affecting endotoxin removal from recombinant therapeutic proteins by anion exchange chromatography
Published in Protein expression and purification (01-03-2009)“…Removal of endotoxins from recombinant proteins is a critical and challenging step in the preparation of injectable therapeutics, as endotoxin is a natural…”
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Expression and purification of the cancer antigen SSX2: A potential cancer vaccine
Published in Protein expression and purification (01-12-2007)“…SSX2 is a cancer testis antigen expressed in a wide variety of cancers, including synovial sarcoma and melanoma. It holds promise as a potential antigen for…”
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Development of an E. coli strain for cell‐free ADC manufacturing
Published in Biotechnology and bioengineering (01-01-2022)“…Recent advances in cell‐free protein synthesis have enabled the folding and assembly of full‐length antibodies at high titers with extracts from prokaryotic…”
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A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems
Published in Biotechnology progress (01-05-2015)“…Cell‐free protein synthesis (CFPS) systems allow for robust protein expression with easy manipulation of conditions to improve protein yield and folding…”
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Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis
Published in Molecular cancer therapeutics (01-06-2016)“…Antibody-drug conjugates (ADC) have generated significant interest as targeted therapeutics for cancer treatment, demonstrating improved clinical efficacy and…”
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A simplified and robust protocol for immunoglobulin expression in E scherichia coli cell‐free protein synthesis systems
Published in Biotechnology progress (01-05-2015)“…Cell‐free protein synthesis (CFPS) systems allow for robust protein expression with easy manipulation of conditions to improve protein yield and folding…”
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