Search Results - "Chen, Qiushu"
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Turbidimetric inhibition immunoassay revisited to enhance its sensitivity via an optofluidic laser
Published in Biosensors & bioelectronics (15-04-2019)“…Turbidimetric inhibition immunoassay (TIIA) is a classic immunodiagnostic method that has been extensively used for biomarker detection. However, the low…”
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2
On-chip, high-sensitivity temperature sensors based on dye-doped solid-state polymer microring lasers
Published in Applied physics letters (07-08-2017)“…We developed a chip-scale temperature sensor with a high sensitivity of 228.6 pm/°C based on a rhodamine 6G (R6G)-doped SU-8 whispering gallery mode microring…”
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3
Optofluidic FRET Lasers and Their Applications in Novel Photonic Devices and Biochemical Sensing
Published in IEEE journal of selected topics in quantum electronics (01-07-2016)“…Incorporating fluorescence resonance energy transfer (FRET) into a laser cavity can increase the sensitivity of FRET-based biochemical sensors due to the…”
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4
Laser-emission imaging of nuclear biomarkers for high-contrast cancer screening and immunodiagnosis
Published in Nature biomedical engineering (2017)“…Detection of nuclear biomarkers, such as nucleic acids and nuclear proteins, is critical for early-stage cancer diagnosis and prognosis. Conventional methods…”
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5
Refractive index sensing based on semiconductor nanowire lasers
Published in Applied physics letters (17-07-2017)“…We demonstrate a refractive index (RI) sensor based on semiconductor nanowire lasers. It is shown that the TE01 mode is responsible for lasing and sensing with…”
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6
Design of an ellipsoidal mirror assisted oblique plane microscopy
Published in Frontiers in physics (11-11-2022)“…Using one objective for excitation and detection simultaneously, oblique plane microscopy (OPM) provides a mounting-friendly approach for optical sectioning…”
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7
Rapid and precise multifocal cutaneous tumor margin assessment using fluorescence lifetime detection and machine learning
Published in APL photonics (01-09-2024)“…The precise determination of surgical margins is essential for the management of multifocal cutaneous cancers, including extramammary Paget’s disease. This…”
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8
Evaluating Differentiation Status of Mesenchymal Stem Cells by Label-Free Microscopy System and Machine Learning
Published in Cells (Basel, Switzerland) (31-05-2023)“…Mesenchymal stem cells (MSCs) play a crucial role in tissue engineering, as their differentiation status directly affects the quality of the final cultured…”
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A digital microfluidic single-cell manipulation system optimized by extending-depth-of-field device
Published in Journal of innovative optical health science (01-05-2023)“…Microfluidic systems have been widely utilized in high-throughput biology analysis, but the difficulties in liquid manipulation and cell cultivation limit its…”
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Highly sensitive optofluidic FRET lasers with genetically encoded fluorescent protein pairs
Published in CLEO: 2013 (01-06-2013)“…We achieved optofluidic FRET lasers using genetically encoded fluorescent protein pairs linked by length-tunable peptides. 10-fold enhancement in the FRET…”
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Conference Proceeding -
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Optofluidic FRET lasers using aqueous quantum dots as donors
Published in Lab on a chip (01-01-2016)“…An optofluidic FRET (fluorescence resonance energy transfer) laser is formed by putting FRET pairs inside a microcavity acting as a gain medium. This…”
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Digital DNA detection based on a compact optofluidic laser with ultra-low sample consumption
Published in Lab on a chip (29-11-2016)“…DNA lasers self-amplify optical signals from a DNA analyte as well as thermodynamic differences between sequences, allowing quasi-digital DNA detection…”
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13
Optofluidic lasers with a single molecular layer of gain
Published in Lab on a chip (21-12-2014)“…We achieve optofluidic lasers with a single molecular layer of gain, in which green fluorescent protein, dye-labeled bovine serum albumin, and dye-labeled DNA,…”
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14
Lasing in blood
Published in Optica (20-08-2016)“…Indocyanine green (ICG) is the near-infrared dye approved by the U.S. Food and Drug Administration for clinical use. When injected in blood, ICG binds…”
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15
Gain controlled optofluidic lasers with self-assembled DNA tetrahedron
Published in CLEO: 2013 (01-06-2013)“…Using self-assembled DNA tetrahedron, we were able to precisely control the gain in optofluidic FRET lasers. 3.8 times reduction in the lasing threshold and…”
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Conference Proceeding -
16
Domain adaptation of time series via contrastive learning with task-specific consistency
Published in Applied intelligence (Dordrecht, Netherlands) (01-12-2024)“…Unsupervised domain adaptation (UDA) for time series analysis remains challenging due to the lack of labeled data in target domains. Existing methods rely…”
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17
Optofluidic laser for dual-mode sensitive biomolecular detection with a large dynamic range
Published in Nature communications (30-04-2014)“…Enzyme-linked immunosorbent assay (ELISA) is a powerful method for biomolecular analysis. The traditional ELISA employing light intensity as the sensing signal…”
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18
Highly sensitive fluorescent protein FRET detection using optofluidic lasers
Published in Lab on a chip (21-07-2013)“…We achieved optofluidic protein lasing using genetically encoded fluorescent protein FRET pairs linked by length-tunable peptides. Up to 25-fold reduction in…”
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19
Bio-inspired optofluidic lasers with luciferin
Published in Applied physics letters (20-05-2013)“…The authors demonstrate a bio-inspired optofluidic laser with luciferin, a class of light-emitting compounds synthesized by many different organisms, as the…”
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20
CoNiCoNC tumor therapy by two-ways producing H2O2 to aggravate energy metabolism, chemokinetics, and ferroptosis
Published in Journal of colloid and interface science (15-01-2025)“…[Display omitted] •CoNiCoNC can catalyze the self-supply of H2O2 from glucose and lactate, alleviating low H2O2 levels in the tumor TME.•CoNiCoNC has the…”
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