Search Results - "Chen, Qimingxing"
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Oral Bioavailability of Kinsenoside in Beagle Dogs Measured by LC-MS/MS: Improvement of Ex Vivo Stability of a Lactone-Containing Compound
Published in Pharmaceutics (09-07-2018)“…Kinsenoside (KD), an active compound isolated from , has demonstrated multiple pharmacological activities including hepatoprotection, antihyperliposis,…”
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Helper-Polymer Based Five-Element Nanoparticles (FNPs) for Lung-Specific mRNA Delivery with Long-Term Stability after Lyophilization
Published in Nano letters (24-08-2022)“…Lipid nanoparticles (LNPs) carrying therapeutic mRNAs hold great promise in treating lung-associated diseases like viral infections, tumors, and genetic…”
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A Precipitation‐Enhanced Emission (PEE) Strategy for Increasing the Brightness and Reducing the Liver Retention of NIR‐II Fluorophores
Published in Small (Weinheim an der Bergstrasse, Germany) (01-12-2022)“…The lack of organic fluorophores with high quantum yields (QYs) and low liver retention in the second near‐infrared (NIR‐II) window has become a bottleneck in…”
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In Vivo Fate of CXCR2-Overexpressing Mesenchymal Stromal/Stem Cells in Pulmonary Diseases Monitored by Near-Infrared Region 2 Imaging
Published in ACS applied materials & interfaces (03-05-2023)“…Lung-associated diseases pose a huge threat to human society. Mesenchymal stromal/stem cells (MSCs) hold great promise in the treatment of pulmonary diseases…”
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A Precipitation‐Enhanced Emission (PEE) Strategy for Increasing the Brightness and Reducing the Liver Retention of NIR‐II Fluorophores (Small 49/2022)
Published in Small (Weinheim an der Bergstrasse, Germany) (08-12-2022)“…NIR‐II Fluorophores In article number 2204153, Weimin Liu, Jianfeng Li, and co‐workers propose a strategy of precipitation‐enhanced emission (PEE). The PEE is…”
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Engineering brain-derived neurotrophic factor mRNA delivery for the treatment of Alzheimer’s disease
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-06-2023)“…•New designed poly (β amino esters) (PBAE) nano-platform can achieve mRNA delivery to brain and spinal cord efficiently.•Stable mRNA secondary structures were…”
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Poly(beta-amino ester)-Based Nanoparticles Enable Nonviral Delivery of Base Editors for Targeted Tumor Gene Editing
Published in Biomacromolecules (09-05-2022)“…Base editing is an emerging genome editing technology with the advantages of precise base corrections, no double-strand DNA breaks, and no need for templates,…”
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Organ-Specific Gene Expression Control Using DNA Origami-Based Nanodevices
Published in Nano letters (10-07-2024)“…Nanodevices that function in specific organs or cells are one of the ultimate goals of synthetic biology. The recent progress in DNA nanotechnology such as DNA…”
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