Search Results - "Chen, Pengqin"

Myeloid Differentiation Primary Response Protein 88 (MyD88): The Central Hub of TLR/IL-1R Signaling by Chen, Lingfeng, Zheng, Lulu, Chen, Pengqin, Liang, Guang

“…Myeloid differentiation primary response protein 88 (MyD88) is a ubiquitously expressed cytoplasmic adaptor protein that plays a central role in the Toll-like…”
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Can cross-regional environmental protection promote urban green development: Zero-sum game or win-win choice? by Zhuo, Chengfeng, Xie, Yuping, Mao, Yanhua, Chen, Pengqin, Li, Yiqiao

“…Forming an effective mechanism of cross-regional environmental protection (CEP) is a feasible way to break the administrative boundary of pollution control and…”
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Design, synthesis and bioactivity evaluation of cinnamic acid derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury by Chen, Pengqin, Chen, Pan, Wang, Xiemin

“…Acute lung injury (ALI), a common critical disease in clinical practice, has a mortality rate as high as 30-40 %, yet currently, no effective treatment methods…”
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Development of 2-amino-4-phenylthiazole analogues to disrupt myeloid differentiation factor 88 and prevent inflammatory responses in acute lung injury by Chen, Lingfeng, Chen, Hongjin, Chen, Pengqin, Zhang, Wenxin, Wu, Chao, Sun, Chuchu, Luo, Wu, Zheng, Lulu, Liu, Zhiguo, Liang, Guang

“…Myeloid differentiation primary response protein 88 (MyD88), an essential adapter protein used by toll-like receptors (TLR), is a promising target molecule for…”
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Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment by Zhang, Jianqing, Chen, Pengqin, Duan, Yongli, Xiong, Hehua, Li, Hongmin, Zeng, Yao, Liang, Guang, Tang, Qidong, Wu, Di

“…In this study, a series of pyrrolo [2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment were synthesized and their biological activity…”
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Surface enhancement of porous alumina microfibers toward electrochemical sensing of chlorogenic acid by Yang, Xiaofeng, Wang, Zhencao, Chen, Pengqin, Sun, Dong

“…Porous alumina microfibers with a diameter of 125 nm were prepared through hydrothermal reaction in urea solution using aluminium nitrate as the precursor, and…”
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Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors by Tang, Qidong, Peng, Ting, Hu, Jie, Zhang, Tao, Chen, Pengqin, Chen, Daoxing, Wang, Yunjie, Chen, Lingfeng, Tong, Linjiang, Chen, Yi, Xie, Hua, Liang, Guang

“…Pan-HER inhibitors exhibit extensive biological activity and offer unique advantages and usually bind to targets in an irreversible manner. Owing to the…”
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Design, synthesis and bioactivity evaluation of fisetin derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury by Wang, Xiemin, Yang, Jun, Ding, Bingyu, Chen, Pan, Xu, Zhengwei, Zhao, Yunxi, Chen, Pengqin, Chattipakorn, Nipon, Liang, Guang, Wu, Di, Tang, Qidong

“…[Display omitted] Acute lung injury (ALI) refers to a common and life-threatening disease attributed to inflammation. However, effective drug treatments have…”
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Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury by Chen, Lingfeng, Jin, Yiyi, Chen, Hongjin, Sun, Chuchu, Fu, Weitao, Zheng, Lulu, Lu, Min, Chen, Pengqin, Chen, Gaozhi, Zhang, Yali, Liu, Zhiguo, Wang, Yi, Song, Zengqiang, Liang, Guang

“…Myeloid differentiation protein 2 (MD2) is an essential molecule which recognizes lipopolysaccharide (LPS), leading to initiation of inflammation through the…”
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Discovery of new cinnamic derivatives as anti‐inflammatory agents for treating acute lung injury in mice by Chen, Pengqin, Xu, Zhengwei, Wang, Xiemin, He, Jie, Yang, Jun, Wang, Jun, Chattipakorn, Nipon, Wu, Di, Tang, Qidong, Liang, Guang, Chen, Ting

“…The blockade of the overexpression of pro‐inflammatory cytokines by anti‐inflammatory natural products has been proven therapeutically beneficial in the…”
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Design, synthesis and anticancer evaluation of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing 1,8-naphthyridine-3-carboxamide moiety as novel multi-target TKIs by Chen, Pengqin, Zhao, Ying, Zhang, Jianqing, Duan, Yongli, Dai, Jintian, He, Jie, Wang, Xiemin, Chen, Xi, Chen, Pan, Zhao, Weixin, Wang, Xu, Zhuang, Zaishou, Yang, Daona, Liang, Guang, Tang, Qidong

“…[Display omitted] •32 novel 6,7-disubstituted-4-phenoxyquinoline derivatives bearing 1,8-naphthyridine-3-carboxamide moiety were designed and synthesized.•The…”
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Spatial distribution of maize in response to climate change in northeast China during 1980-2010 by Li, Zhengguo, Tan, Jieyang, Tang, Pengqin, Chen, Hao, Zhang, Li, Liu, Han, Wu, Wenbin, Tang, Huajun, Yang, Peng, Liu, Zhenhuan

“…Based on county-level crop statistics and other ancillary information, spatial distri- bution of maize in the major maize-growing areas （latitudes 39°-48°N）…”
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