Search Results - "Chen, Paul Z"
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Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols
Published in eLife (16-04-2021)“…Which virological factors mediate overdispersion in the transmissibility of emerging viruses remains a long-standing question in infectious disease…”
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SARS-CoV-2 shedding dynamics across the respiratory tract, sex, and disease severity for adult and pediatric COVID-19
Published in eLife (20-08-2021)“…Previously, we conducted a systematic review and analyzed the respiratory kinetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Chen et…”
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Effect of moist heat reprocessing of N95 respirators on SARS-CoV-2 inactivation and respirator function
Published in Canadian Medical Association journal (CMAJ) (13-10-2020)“…Unprecedented demand for N95 respirators during the coronavirus disease 2019 (COVID-19) pandemic has led to a global shortage of these masks. We validated a…”
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Understanding why superspreading drives the COVID-19 pandemic but not the H1N1 pandemic
Published in The Lancet infectious diseases (01-09-2021)“…Generally, k remains similar across distinct outbreaks of a virus.1 Studies have documented this for SARS-CoV-2, including across disparate geographical…”
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From prevention to diagnosis and treatment: Biomedical applications of metal nanoparticle-hydrogel composites
Published in Acta biomaterialia (01-03-2021)“…Recent advances in biomaterials integrate metal nanoparticles with hydrogels to generate composite materials that exhibit new or improved properties. By…”
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Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
Published in Nature biotechnology (08-01-2024)“…Prime editing enables precise installation of genomic substitutions, insertions and deletions in living systems. Efficient in vitro and in vivo delivery of…”
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Asymmetric Interfacet Adatom Migration as a Mode of Anisotropic Nanocrystal Growth
Published in Journal of the American Chemical Society (26-10-2022)“…Crystals are known to grow nonclassically or via four classical modes (the layer-by-layer, dislocation-driven, dendritic, and normal modes, which generally…”
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Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli–induced Acute Lung Injury in Rats
Published in Anesthesiology (Philadelphia) (01-05-2019)“…WHAT WE ALREADY KNOW ABOUT THIS TOPIC WHAT THIS ARTICLE TELLS US THAT IS NEW BACKGROUND:Human umbilical cord mesenchymal stromal cells possess considerable…”
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Low-Fouling Characteristics of Ultrathin Zwitterionic Cysteine SAMs
Published in Langmuir (05-02-2019)“…Surface fouling remains an exigent issue for many biological implants. Unwanted solutes adsorb to reduce device efficiency and hasten degradation while…”
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“Chemical nose” for the visual identification of emerging ocular pathogens using gold nanostars
Published in Biosensors & bioelectronics (15-11-2014)“…Ocular pathogens can cause serious damages in the eye leading to severe vision loss and even blindness if left untreated. Identification of pathogens is…”
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Micro-a-fluidics ELISA for Rapid CD4 Cell Count at the Point-of-Care
Published in Scientific reports (22-01-2014)“…HIV has become one of the most devastating pathogens in human history. Despite fast progress in HIV-related basic research, antiretroviral therapy (ART)…”
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Untangling Mucosal Drug Delivery: Engineering, Designing, and Testing Nanoparticles to Overcome the Mucus Barrier
Published in ACS biomaterials science & engineering (11-04-2022)“…Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in the human body. High vascularization and accessibility have…”
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Polymer Co‐Coating of Gold Nanoparticles Enables Their Integration Into Contact Lenses for Stable, Selective Ocular Light Filters
Published in Advanced materials interfaces (01-11-2022)“…Chronic exposure to long‐wavelength (red) light is associated with increased incidence and progression of myopia in preclinical models. Contact lenses are worn…”
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A "chemical nose" biosensor for detecting proteins in complex mixtures
Published in Analyst (London) (07-10-2016)“…A growing understanding of the fundamental role of proteins in diseases has advanced the development of quantitative protein assays in the medical field…”
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Theoretical framework and experimental methodology to elucidate the supersaturation dynamics of nanocrystal growth
Published in Nanoscale horizons (28-03-2022)“…Supersaturation is the fundamental parameter driving crystal formation, yet its dynamics in the growth of colloidal nanocrystals (NCs) remain poorly…”
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Interactions between bacterial surface and nanoparticles govern the performance of “chemical nose” biosensors
Published in Biosensors & bioelectronics (15-09-2016)“…Rapid and portable diagnosis of pathogenic bacteria can save lives lost from infectious diseases. Biosensors based on a “chemical nose” approach are attracting…”
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To hide or to feed: an evaluation of personality traits in the sand bubbler crab, Dotilla wichmanni, when responding to environmental interference
Published in Behavioural processes (01-07-2019)“…•Environmental disruptions can interfere with sand bubbler crabs’ survival.•Behaviours function crucially in crab’s ability to cope with such…”
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Mangrove crab uses victory display to “browbeat” losers from re‐initiating a new fight
Published in Ethology (01-12-2017)“…Signalling behaviour is integral to animal contests. However, post‐contest signals, such as victory displays, have received relatively little attention. One…”
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Post‐Contest Stridulation Used Exclusively as a Victory Display in Mangrove Crabs
Published in Ethology (01-06-2014)“…Victory or triumph display is a post‐contest signal, performed only by winners and not by losers. While much is unknown about its function, there is mounting…”
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