Search Results - "Chen, Naihong"
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Hepataprotective effects of ginsenoside Rg1 – A review
Published in Journal of ethnopharmacology (12-07-2017)“…Ginseng has been used as efficient tonic and for the treatment of various diseases including hepatic disorders. Ginseng saponins, also known as ginsenosides,…”
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Anticancer property of ginsenoside Rh2 from ginseng
Published in European journal of medicinal chemistry (01-10-2020)“…Ginseng has been used as a well-known traditional Chinese medicine since ancient times. Ginsenosides as its main active constituents possess a broad scope of…”
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3
Perspective and Therapeutic Potential of the Noncoding RNA-Connexin Axis
Published in International journal of molecular sciences (01-06-2024)“…Noncoding RNAs (ncRNAs) are a class of nucleotide sequences that cannot be translated into peptides. ncRNAs can function post-transcriptionally by splicing…”
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A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis
Published in Cells (Basel, Switzerland) (18-07-2019)“…Many cancer patients suffer from severe fatigue when treated with chemotherapy or radiotherapy; however, the etiology and pathogenesis of this kind of fatigue…”
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Neuroinflammatory In Vitro Cell Culture Models and the Potential Applications for Neurological Disorders
Published in Frontiers in pharmacology (23-04-2021)“…Cell cultures are used in pharmaceutical, medical and biological sciences. Due to the ethical and cost limitations of models, the replaceable cell model that…”
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Tunneling nanotubes: The transport highway for astrocyte-neuron communication in the central nervous system
Published in Brain research bulletin (01-04-2024)“…Tunneling nanotubes (TNTs) have emerged as pivotal structures for intercellular communication, enabling the transfer of cellular components across distant…”
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Neurotrophic basis to the pathogenesis of depression and phytotherapy
Published in Frontiers in pharmacology (06-04-2023)“…Depression is a major neuropsychiatric disease that considerably impacts individuals' psychosocial function and life quality. Neurotrophic factors are now…”
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Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice
Published in Free radical research (02-01-2017)“…Oxidative stress is mainly caused by reactive oxygen species (ROS). The damage causes a net stress on normal organs, leading to a gradual loss of vital…”
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Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease
Published in Journal of translational medicine (02-08-2023)“…Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality rates, encompassing conditions like pulmonary arterial hypertension…”
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Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression
Published in Frontiers in pharmacology (05-08-2021)“…Depression is an inflammation-associated disease that results in major depression as inflammation increases and progresses. Ginsenoside Rg1 (Rg1), the major…”
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CZK, a novel alkaloid derivative from Clausena lansium, alleviates ischemic stroke injury through Nrf2-mediated antioxidant effects
Published in Scientific reports (13-04-2023)“…Anti-oxidant stress is a potential strategy for the treatment of ischemic stroke. Here, we found a novel free radical scavenger termed as CZK, which is derived…”
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Mechanism of Dihydromyricetin on Inflammatory Diseases
Published in Frontiers in pharmacology (18-01-2022)“…Inflammation plays a crucial role in a variety of diseases, including diabetes, arthritis, asthma, Alzheimer's disease (AD), acute cerebral stroke, cancer,…”
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13
Lignans and Neolignans from Sinocalamus affinis and Their Absolute Configurations
Published in Journal of natural products (Washington, D.C.) (27-05-2011)“…Twenty-two new lignans and neolignans (1−22), together with 14 known analogues, have been isolated from an ethanolic extract of the stem (with skin removed) of…”
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14
The raphe nuclei are the early lesion site of gastric α -synuclein propagation to the substantia nigra
Published in Acta pharmaceutica Sinica. B (01-05-2024)“…Parkinson's disease (PD) is a neurodegeneration disease with -synuclein accumulated in the substantia nigra pars compacta (SNpc) and most of the dopaminergic…”
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Anti-inflammatory function of ginsenoside Rg1 on alcoholic hepatitis through glucocorticoid receptor related nuclear factor-kappa B pathway
Published in Journal of ethnopharmacology (15-09-2015)“…Ginseng is the dried root of Panax ginseng C.A. Mayer. Since ancient times, ginseng has been used as one kind of treatment drug or tonic in China and even…”
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Ferroptosis is Involved in the Pharmacological Effect of Ginsenoside
Published in Mini reviews in medicinal chemistry (01-01-2024)“…Ginsenoside is the principal active ingredient in ginseng. Several investigations have found that ginsenosides have anti-inflammatory, antioxidant,…”
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A Review of Research on the Association between Neuron-Astrocyte Signaling Processes and Depressive Symptoms
Published in International journal of molecular sciences (01-04-2023)“…Depression is a mental illness that has a serious negative impact on physical and mental health. The pathophysiology of depression is still unknown, and…”
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Early Stage Functions of Mitochondrial Autophagy and Oxidative Stress in Acetaminophen‐Induced Liver Injury
Published in Journal of cellular biochemistry (01-10-2017)“…ABSTRACT Mitochondria go through frequent cycles of fusion and fission, a process required for mitochondrial quality control by eliminating ROS‐damaged…”
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Corrigendum: Ginsenoside Rg1 ameliorates neuroinflammation via suppression of connexin43 ubiquitination to attenuate depression
Published in Frontiers in pharmacology (17-07-2024)“…[This corrects the article DOI: 10.3389/fphar.2021.709019.]…”
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Novel antidepressant mechanism of hypericin: Role of connexin 43-based gap junctions
Published in Biomedicine & pharmacotherapy (01-11-2023)“…Hypericin is widely utilized for its precise antidepressant properties, but its exact antidepressant mechanism remains unclear. Gap junctions, which were…”
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