Search Results - "Chen, Naifei"
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Mechanisms of Cancer Resistance to Immunotherapy
Published in Frontiers in oncology (06-08-2020)“…Over the last decade, based on the extensive development of preclinical animal studies and clinical trials, the efficacy, and mechanisms of immunotherapy have…”
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A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1
Published in Genome Biology (11-12-2018)“…Friend leukemia virus integration 1 (FLI1), an ETS transcription factor family member, acts as an oncogenic driver in hematological malignancies and promotes…”
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3
FLI1 Exonic Circular RNAs as a Novel Oncogenic Driver to Promote Tumor Metastasis in Small Cell Lung Cancer
Published in Clinical cancer research (15-02-2019)“…The aberrantly upregulated Friend leukemia virus integration 1 ( ) is closely correlated with the malignant phenotype of small cell lung cancer (SCLC). It is…”
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Molecular classification of small cell lung cancer subtypes: Characteristics, prognostic factors, and clinical translation
Published in Chinese medical journal (20-01-2024)“…Small cell lung cancer (SCLC) is a highly malignant tumor with a very poor prognosis; therefore, more effective treatments are urgently needed for patients…”
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Efficacy and Safety of Epidermal Growth Factor Receptor (EGFR) Inhibitors Plus Antiangiogenic Agents as First-Line Treatments for Patients With Advanced EGFR-Mutated Non-small Cell Lung Cancer: A Meta-Analysis
Published in Frontiers in oncology (25-06-2020)“…Background: Tyrosine kinase inhibitors (TKIs) are standard treatment options for non-small cell lung cancer (NSCLC) with epidermal growth factor receptor…”
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Neoadjuvant and Adjuvant Immunotherapy: Opening New Horizons for Patients With Early-Stage Non-small Cell Lung Cancer
Published in Frontiers in oncology (09-10-2020)“…Lung cancer is the most common malignant tumor with the highest mortality, and about 84% are non-small cell lung cancer (NSCLC). However, only a small…”
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Exposure to air pollution, genetic susceptibility, and prevalence of sarcopenia in the UK
Published in Ecotoxicology and environmental safety (15-10-2024)“…The role of environmental factors, particularly air pollutants, in the prevalence of sarcopenia remains unclear. This study explored the relationship between…”
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Nerves in the Tumor Microenvironment: Origin and Effects
Published in Frontiers in cell and developmental biology (17-12-2020)“…Studies have reported the vital role of nerves in tumorigenesis and cancer progression. Nerves infiltrate the tumor microenvironment thereby enhancing cancer…”
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A Neutrophil Extracellular Traps Signature Predicts the Clinical Outcomes and Immunotherapy Response in Head and Neck Squamous Cell Carcinoma
Published in Frontiers in molecular biosciences (18-02-2022)“…Neutrophil extracellular traps (NETs) play an important role in the occurrence, metastasis and immune escape of cancers. This study aimed to investigate…”
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Direct oral anticoagulants versus low molecular weight heparins for the treatment of cancer-associated thrombosis: a cost-effectiveness analysis
Published in Thrombosis journal (29-09-2021)“…Abstract Background Recently, direct oral anticoagulants (DOACs) have been included in guidelines for the treatment of cancer-associated thrombosis (CAT) to be…”
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Clinical Progress of PD-1/L1 Inhibitors in Breast Cancer Immunotherapy
Published in Frontiers in oncology (06-01-2022)“…Breast cancer is a major killer of women's health worldwide. While breast cancer is thought to have lower immunogenicity compared with other solid tumors,…”
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Prognostic value of MICA/B in cancers: a systematic review and meta-analysis
Published in Oncotarget (10-11-2017)“…MHC class I chain related-proteins A (MICA) and B (MICB) are natural killer group 2D ligands that mediate tumor surveillance. Several studies have suggested…”
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Serum klotho as a novel biomarker for metabolic syndrome: findings from a large national cohort
Published in Frontiers in endocrinology (Lausanne) (04-03-2024)“…Metabolic syndrome is a cluster of metabolic abnormalities that significantly increase the risk of cardiovascular disease and mortality. The identification of…”
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SARS-CoV-2 spike protein induces the cytokine release syndrome by stimulating T cells to produce more IL-2
Published in Frontiers in immunology (18-09-2024)“…Cytokine release syndrome (CRS) is one of the leading causes of mortality in patients with COVID-19 caused by the SARS-CoV-2 coronavirus. However, the…”
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Revisiting the mechanisms linking blood glucose to cognitive impairment: new evidence for the potential important role of klotho
Published in Frontiers in endocrinology (Lausanne) (05-03-2024)“…The association between blood glucose and cognition is controversial. Klotho is an anti-aging protein with neural protective effects. This study aimed to use a…”
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Single Nucleotide Polymorphisms in HOTAIR Are Related to Breast Cancer Risk and Prognosis in the Northeastern Chinese Population
Published in Frontiers in oncology (12-07-2021)“…Background The long noncoding RNA HOX transcript antisense RNA ( HOTAIR ) is highly expressed in breast cancer (BC) tissues and is associated with the…”
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Novel Frontiers of Treatment for Advanced Gastric or Gastroesophageal Junction Cancer (GC/GEJC): Will Immunotherapy Be a Future Direction?
Published in Frontiers in oncology (21-07-2020)“…Considering the limited progress of chemotherapy and targeted therapy in improving the generally disappointing outcomes of advanced gastric or gastroesophageal…”
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Chromatin lncRNA Platr10 controls stem cell pluripotency by coordinating an intrachromosomal regulatory network
Published in Genome Biology (19-08-2021)“…A specific 3-dimensional intrachromosomal architecture of core stem cell factor genes is required to reprogram a somatic cell into pluripotency. As little is…”
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Sintilimab plus autologous NK cells as second-line treatment for advanced non-small-cell lung cancer previous treated with platinum-containing chemotherapy
Published in Frontiers in immunology (08-12-2022)“…This pilot study (NCT03958097; https://www.clinicaltrials.gov/ct2/show/NCT03958097) was aimed to evaluate the efficacy and safety of PD-1 antibody combined…”
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Analysis of characteristics and predictive factors of immune checkpoint inhibitor-related adverse events
Published in Cancer biology & medicine (01-11-2021)“…We aimed to retrospectively analyze the toxicity profiles and predictors of immune-related adverse events (irAEs) as well as the correlation between irAEs and…”
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