Search Results - "Chen, Mingkang"
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Single-Cell Transcriptomics Reveals Novel Role of Microglia in Fibrovascular Membrane of Proliferative Diabetic Retinopathy
Published in Diabetes (New York, N.Y.) (01-04-2022)“…Vitreous fibrovascular membranes (FVMs), the hallmark of proliferative diabetic retinopathy (PDR), cause retinal hemorrhage, detachment, and eventually…”
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CRB2 mutation causes autosomal recessive retinitis pigmentosa
Published in Experimental eye research (01-03-2019)“…Retinitis pigmentosa (RP), the most common form of inherited retinal dystrophies, exhibits significant genetic heterogeneity. The crumbs homolog 2 (CRB2)…”
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Identification of a novel GPR143 mutation in a large Chinese family with isolated foveal hypoplasia
Published in BMC ophthalmology (30-03-2021)“…Pathogenic variants of G-protein coupled receptor 143 (GPR143) gene often leads to ocular albinism type I (OA1) characterized by nystagmus, iris and fundus…”
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4
B Cells and IL-21-Producing Follicular Helper T Cells Cooperate to Determine the Dynamic Alterations of Premetastatic Tumor Draining Lymph Nodes of Breast Cancer
Published in Research (Washington) (2024)“…Metastasis is the major cause of cancer-related death, and lymph node is the most common site of metastasis in breast cancer. However, the alterations that…”
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Weather-aware object detection method for maritime surveillance systems
Published in Future generation computer systems (01-02-2024)“…The development of machine learning-based maritime object detection technology aims to assist ship operators in maritime surveillance. However, as maritime…”
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Theoretical modification of the laboratory-determined tensile stress–strain relationship of strain hardening cementitious composites (SHCCs) for large-scale specimens
Published in Construction & building materials (04-04-2022)“…•Evaluate the effect of the specimen width and thickness on the fiber orientation.•Closed-form probability distribution models for fiber orientations were…”
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Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Published in Differentiation (London) (01-07-2023)“…Retinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal…”
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Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection
Published in Fish & shellfish immunology (01-07-2019)“…Japanese pufferfish (Takifugu rubripes) is one of the main marine aquatic fish species cultured in Asia due to its high nutritional value. In recent years,…”
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Single-Cell Transcriptomic Profiling of Human Retinal Organoids Revealed a Role of IGF1-PHLDA1 Axis in Photoreceptor Precursor Specification
Published in Investigative ophthalmology & visual science (01-11-2022)“…PurposeCone and rod photoreceptors in the retina convert light to electrical signals which are transmitted to the visual cortex of the brain. Abnormal…”
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10
Runoff variation and its attribution analysis in the typical basin of Loess Plateau at multiple temporal and spatial scales
Published in Journal of hydrology. Regional studies (01-12-2024)“…Dali River Basin, a typical basin on the Loess Plateau (LP) in China The LP has undergone extensive ecological management in recent decades, significantly…”
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Transcriptome profiling of the low-salinity stress responses in the gills of the juvenile Pseudopleuronectes yokohamae
Published in Comparative biochemistry and physiology. Part D, Genomics & proteomics (01-12-2019)“…Salinity is an important environmental factor that affects the life cycle of fish, including their growth, development and reproduction. The marbled flounder,…”
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Molecular characterization and expression analysis of galectins in Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection
Published in Fish & shellfish immunology (01-03-2019)“…Galectins are a family of proteins with conserved carbohydrate recognition domains (CRDs) that bind to specific glycans, including the glycans on the surface…”
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13
Molecular characterization and expression analysis of the interleukin 1b gene in Pacific cod (Gadus macrocephalus)
Published in Developmental and comparative immunology (01-11-2018)“…Interleukin 1b (IL-1b) is a member of the cytokine family that serves as major mediators for early pro-inflammatory responses. During artificial breeding of…”
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Somatostatin signalling promotes the differentiation of rod photoreceptors in human pluripotent stem cell‐derived retinal organoid
Published in Cell proliferation (01-07-2022)“…Objectives Stem cell‐derived photoreceptor replacement therapy is a promising strategy for the treatment of retinal degenerative disease. The development of 3D…”
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The Role of Adaptive Immunity in Diabetic Retinopathy
Published in Journal of clinical medicine (02-11-2022)“…Diabetic retinopathy (DR) is currently one of the common causes of vision loss in working-age adults. It is clinically diagnosed and classified according to…”
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Angiogenic and Fibrogenic Dual-effect of Gremlin1 on Proliferative Diabetic Retinopathy
Published in International journal of biological sciences (2024)“…Ocular angiogenic diseases, such as proliferative diabetic retinopathy (PDR), are often characterized by pathological new vessels and fibrosis formation…”
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pH-sensitive peptide hydrogel encapsulating the anti-angiogenesis drug conbercept and chemotherapeutic drug dox as a combination therapy for retinoblastoma
Published in Materials advances (04-03-2024)“…Retinoblastoma (RB) is a malignant tumor originating from the retina. Radiotherapy, chemotherapy, photodynamic therapy, cryotherapy, and surgery are commonly…”
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An adaptive policy-driven middleware for mobile computing
“…The recent trend in mobile computing has led to complex environments, and requirements which are changed dynamically. Adaptation is a solution for complex, and…”
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Conference Proceeding -
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Efficient Semantic Segmentation Backbone Evaluation for Unmanned Surface Vehicles based on Likelihood Distribution Estimation
Published in 2022 18th International Conference on Mobility, Sensing and Networking (MSN) (01-12-2022)“…Obstacle detection using semantic segmentation shows a great promise for unmanned surface vehicles(USVs) in unstable marine environments. Unlike traditional…”
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Conference Proceeding -
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Multi-Weather Classification using Evolutionary Algorithm on EfficientNet
Published in 2021 IEEE International Conference on Pervasive Computing and Communications Workshops and other Affiliated Events (PerCom Workshops) (22-03-2021)“…Complex weather factors seriously affect the quality and accuracy of image processing, and indirectly pose severe challenges to the expansion of IoT…”
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Conference Proceeding