Search Results - "Chen, Meibo W."
-
1
Histone Deacetylase 3 Is Required for T Cell Maturation
Published in The Journal of immunology (1950) (15-08-2015)“…Recent thymic emigrants are newly generated T cells that need to undergo postthymic maturation to gain functional competency and enter the long-lived naive T…”
Get full text
Journal Article -
2
HDAC3 Is Required for the Downregulation of RORγt during Thymocyte Positive Selection
Published in The Journal of immunology (1950) (15-07-2016)“…To generate functional peripheral T cells, proper gene regulation during T cell development is critical. In this study, we found that histone deacetylase…”
Get full text
Journal Article -
3
NKAP Regulates Invariant NKT Cell Proliferation and Differentiation into ROR-γt-Expressing NKT17 Cells
Published in The Journal of immunology (1950) (15-06-2016)“…Invariant NKT (iNKT) cells are a unique lineage with characteristics of both adaptive and innate lymphocytes, and they recognize glycolipids presented by an…”
Get full text
Journal Article -
4
Immature recent thymic emigrants are eliminated by complement
Published in The Journal of immunology (1950) (15-12-2014)“…Recent thymic emigrants (RTEs) must undergo phenotypic and functional maturation to become long-lived mature naive T cells. In CD4-cre NKAP conditional…”
Get full text
Journal Article -
5
An Essential Role for the Transcription Factor Runx1 in T Cell Maturation
Published in Scientific reports (29-03-2016)“…The transcription factor Runx1 has essential roles throughout hematopoiesis. Here, we demonstrate that Runx1 is critical for T cell maturation. Peripheral…”
Get full text
Journal Article -
6
HDAC3 is required for the down-regulation of RORγt during thymocyte positive selection
Published in The Journal of immunology (1950) (08-06-2016)“…To generate functional peripheral T cells, proper gene regulation during T cell development is critical. Here, we found that histone deacetylase 3 (HDAC3) is…”
Get full text
Journal Article -
7
NKAP regulates iNKT cell proliferation and differentiation into ROR-γt expressing NKT17 cells
Published in The Journal of immunology (1950) (09-05-2016)“…Invariant Natural Killer T (iNKT) cells are a unique lineage with characteristics of both adaptive and innate lymphocytes, and recognize glycolipid presented…”
Get full text
Journal Article -
8
HDAC3 is required for T cell maturation1
Published in The Journal of immunology (1950) (10-07-2015)“…Recent thymic emigrants (RTEs) are newly generated T cells that need to undergo post-thymic maturation to gain functional competency and enter the long-lived…”
Get full text
Journal Article -
9
Immature recent thymic emigrants are eliminated by complement1
Published in The Journal of immunology (1950) (03-11-2014)“…Recent thymic emigrants (RTEs) must undergo phenotypic and functional maturation to become long-lived mature naïve T cells. In CD4-cre NKAP conditional…”
Get full text
Journal Article