Search Results - "Chen, Luke Y.C"

Hemophagocytic syndromes (HPS) including Hemophagocytic Lymphohistiocytosis (HLH) in Adults: A Systematic Scoping Review by Hayden, Anna, Park, Sujin, Giustini, Dean, Lee, Agnes Y.Y, Chen, Luke Y.C

“…Abstract Most knowledge of hemophagocytic syndromes (HPS) including hemophagocytic lymphohistiocytosis (HLH) is derived from pediatric studies; literature on…”
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Innovations in genomics for undiagnosed diseases: vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome by Stubbins, Ryan J, Cherniawsky, Hannah, Chen, Luke Y C, Nevill, Thomas J

“…Stubbins et al illustrate the power of genomics to affect clinical diagnostics and practice with the newly discovered vacuoles, E1 enzyme, X-linked,…”
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Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome by Chen, Luke Y C, Hoiland, Ryan L, Stukas, Sophie, Wellington, Cheryl L, Sekhon, Mypinder S

“…The concept of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome (COVID-CSS) emerged early in the severe acute respiratory syndrome…”
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IgG4-related disease: what a hematologist needs to know by Chen, Luke Y C, Mattman, Andre, Seidman, Michael A, Carruthers, Mollie N

“…IgG4-related disease is a fibro-inflammatory condition that can affect nearly any organ system. Common presentations include major salivary and lacrimal gland…”
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TAFRO subtype of idiopathic multicentric Castleman disease in a 22-year-old man by Rowe, Steven, Collins, Brandon Wayne, Pirzada, Amrah, Manning, Neal, Chen, Luke Y.C

“…A 22-year-old man presented to the emergency department with symptoms of fatigue, abdominal pain, constipation, and difficulty breathing. He had gained weight…”
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Tocilizumab for hospitalized patients with COVID-19 by Afra, Kevin, Chen, Luke Y C, Sweet, David

“…Afra et al present several facts about the effectiveness of tocilizumab for patients with COVID-19. Among other things, tocilizumab is an immunomodulatory drug…”
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Clinical utility of soluble interleukin-2 receptor in hemophagocytic syndromes: a systematic scoping review by Lin, Molly, Park, Sujin, Hayden, Anna, Giustini, Dean, Trinkaus, Martina, Pudek, Morris, Mattman, Andre, Schneider, Marion, Chen, Luke Y.C.

“…The serum-soluble interleukin-2 receptor (sIL-2r) level is considered an important diagnostic test and disease marker in hemophagocytic…”
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Amelioration of COVID‐19‐related cytokine storm syndrome: parallels to chimeric antigen receptor‐T cell cytokine release syndrome by Hoiland, Ryan L., Stukas, Sophie, Cooper, Jennifer, Thiara, Sonny, Chen, Luke Y. C., Biggs, Catherine M., Hay, Kevin, Lee, Agnes Y. Y., Shojania, Kamran, Abdulla, Alym, Wellington, Cheryl L., Sekhon, Mypinder S.

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Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH by Hayden, Anna, Lin, Molly, Park, Sujin, Pudek, Morris, Schneider, Marion, Jordan, Michael B., Mattman, Andre, Chen, Luke Y.C.

“…Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published data on…”
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Le tocilizumab pour les patients hospitalises atteints de la COVID-19 by Afra, Kevin, Chen, Luke Y.C, Sweet, David

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Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome by Chen, Luke Y.C., Biggs, Catherine M., Jamal, Shahin, Stukas, Sophie, Wellington, Cheryl L., Sekhon, Mypinder S.

“…Data suggest that interleukin (IL)-6 blockade could reduce mortality in severe COVID-19, yet IL-6 is only modestly elevated in most patients. Chen et al…”
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Method Limitations in LC-MS/MS and Immunonephelometric Measurement of IgG Subclasses by van der Gugten, Grace, Mattman, Andre, Ritchie, Gordon, Chen, Luke Y C, Chin, Alex, Holmes, Daniel T, Mills, John R, Rao, Lokinendi V

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Utility of Serum IgG4 Levels in a Multiethnic Population by Qi, Ruyu, Chen, Luke Y.C., Park, Sujin, Irvine, Robert, Seidman, Michael A., Kelsall, John T., Collins, David, Yin, Vivian, Slack, Graham W., Mattman, Andre, Lam, Eric, Carruthers, Mollie N.

“…IgG4-related disease (IgG4-RD) is a recently recognized condition defined by characteristic histopathologic findings in affected organs. Serum IgG4…”
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IgG4‐related disease and lymphocyte‐variant hypereosinophilic syndrome: A comparative case series by Carruthers, Mollie N., Park, Sujin, Slack, Graham W., Dalal, Bakul I., Skinnider, Brian F., Schaeffer, David F., Dutz, Jan P., Law, Joanna K., Donnellan, Fergal, Marquez, Vladimir, Seidman, Michael, Wong, Patrick C., Mattman, Andre, Chen, Luke Y.C.

“…Objective To compare the clinical and laboratory features of IgG4‐related disease (IgG4‐RD) and lymphocyte‐variant hypereosinophilic syndrome (L‐HES), two rare…”
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Lymphocyte-Variant Hypereosinophilic Syndrome With Eosinophilic Myocarditis Treated With Steroids and Pegylated Interferon Alfa-2a by Cheung, Christopher C., Constantine, Maggie, Ahmadi, Amir, Shiau, Carolyn, Chen, Luke Y.C.

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Residents’ Views of the Role of Classroom-Based Learning in Graduate Medical Education Through the Lens of Academic Half Days by Chen, Luke Y.C, McDonald, Julie A, Pratt, Daniel D, Wisener, Katherine M, Jarvis-Selinger, Sandra

“…PURPOSETo examine the role of classroom-based learning in graduate medical education through the lens of academic half days (AHDs) by exploring residents’…”
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Innovations en génomique pour les maladies non diagnostiquées: le syndrome VEXAS (vacuoles intracytoplasmiques dans les progéniteurs médullaires, E1 ubiquitine ligase, liée à l’X, syndrome auto-inflammatoire, mutation somatique) by Stubbins, Ryan J, Cherniawsky, Hannah, Chen, Luke Y.C, Nevill, Thomas J

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Reduced fixed dose tocilizumab 400 mg IV compared to weight-based dosing in critically ill patients with COVID-19: A before-after cohort study by Stukas, Sophie, Goshua, George, Kinkade, Angus, Grey, Rebecca, Mah, Gregory, Biggs, Catherine M., Jamal, Shahin, Thiara, Sonny, Lau, Tim T.Y., Piszczek, Jolanta, Partovi, Nilu, Sweet, David D, Lee, Agnes Y.Y., Wellington, Cheryl L., Sekhon, Mypinder S., Chen, Luke Y.C.

“…Interleukin-6 inhibitors reduce mortality in severe COVID-19. British Columbia began using tocilizumab 8 mg/kg (maximum 800 mg) in January 2021 in critically…”
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Etoposide‐based treatment of adult HLH is associated with high biochemical response but poor survival outcomes by Nicholson, Matthew C., Naeije, Leonie, Hayden, Anna R., Mattman, Andre, Dix, David, Chen, Luke Y.C.

“…Etoposide‐based treatment is the standard of care for adult HLH in many centers, yet there remains a paucity of data regarding treatment outcomes. We conducted…”
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Confirmed Efficacy of Lenalidomide and Dexamethasone in Unresectable Cutaneous Facial Rosai-Dorfman-Destombes Disease by Al-Ghawas, Mae S., Ng, Tony, Chen, Luke Y.C.

“…Rosai-Dorfman-Destombes disease is a rare nonmalignant histiocytic condition. Cutaneous disease is common and typically treated with surgical resection, but…”
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