Search Results - "Chen, Luke"

Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome by Chen, Luke Y C, Hoiland, Ryan L, Stukas, Sophie, Wellington, Cheryl L, Sekhon, Mypinder S

“…The concept of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome (COVID-CSS) emerged early in the severe acute respiratory syndrome…”
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Hemophagocytic syndromes (HPS) including Hemophagocytic Lymphohistiocytosis (HLH) in Adults: A Systematic Scoping Review by Hayden, Anna, Park, Sujin, Giustini, Dean, Lee, Agnes Y.Y, Chen, Luke Y.C

“…Abstract Most knowledge of hemophagocytic syndromes (HPS) including hemophagocytic lymphohistiocytosis (HLH) is derived from pediatric studies; literature on…”
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IgG4-related disease: what a hematologist needs to know by Chen, Luke Y C, Mattman, Andre, Seidman, Michael A, Carruthers, Mollie N

“…IgG4-related disease is a fibro-inflammatory condition that can affect nearly any organ system. Common presentations include major salivary and lacrimal gland…”
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Clinical utility of soluble interleukin-2 receptor in hemophagocytic syndromes: a systematic scoping review by Lin, Molly, Park, Sujin, Hayden, Anna, Giustini, Dean, Trinkaus, Martina, Pudek, Morris, Mattman, Andre, Schneider, Marion, Chen, Luke Y.C.

“…The serum-soluble interleukin-2 receptor (sIL-2r) level is considered an important diagnostic test and disease marker in hemophagocytic…”
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Innovations in genomics for undiagnosed diseases: vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome by Stubbins, Ryan J, Cherniawsky, Hannah, Chen, Luke Y C, Nevill, Thomas J

“…Stubbins et al illustrate the power of genomics to affect clinical diagnostics and practice with the newly discovered vacuoles, E1 enzyme, X-linked,…”
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Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes by England, James T., Abdulla, Alym, Biggs, Catherine M., Lee, Agnes Y.Y., Hay, Kevin A., Hoiland, Ryan L., Wellington, Cheryl L., Sekhon, Mypinder, Jamal, Shahin, Shojania, Kamran, Chen, Luke Y.C.

“…A subset of patients with severe COVID-19 develop profound inflammation and multi-organ dysfunction consistent with a “Cytokine Storm Syndrome” (CSS). In this…”
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TAFRO subtype of idiopathic multicentric Castleman disease in a 22-year-old man by Rowe, Steven, Collins, Brandon Wayne, Pirzada, Amrah, Manning, Neal, Chen, Luke Y.C

“…A 22-year-old man presented to the emergency department with symptoms of fatigue, abdominal pain, constipation, and difficulty breathing. He had gained weight…”
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Tocilizumab for hospitalized patients with COVID-19 by Afra, Kevin, Chen, Luke Y C, Sweet, David

“…Afra et al present several facts about the effectiveness of tocilizumab for patients with COVID-19. Among other things, tocilizumab is an immunomodulatory drug…”
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VEXAS syndrome in a female patient with constitutional 45,X (Turner syndrome) by Stubbins, Ryan J, McGinnis, Eric, Johal, Bhupinder, Chen, Luke Yc, Wilson, Lorena, Cardona, Daniela Ospina, Nevill, Thomas J

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COVID-19, haemophagocytic lymphohistiocytosis, and infection-induced cytokine storm syndromes by Spaner, Caroline, Goubran, Mariam, Setiadi, Audi, Chen, Luke Y C

“…Recent research in COVID-19 cytokine storm syndrome and Castleman disease has expanded the concept of pathological immune activation and established important…”
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Treatment of lymphocyte‐variant hypereosinophilic syndrome (L‐HES): what to consider after confirming the elusive diagnosis by Williams, Alastair K., Dou, Carol, Chen, Luke Y. C.

“…Summary Lymphocyte‐variant hypereosinophilic syndrome (L‐HES) is a rare disease driven by immunophenotypically aberrant T cells producing eosinophilopoetic…”
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Ruxolitinib as adjunctive therapy for secondary hemophagocytic lymphohistiocytosis: A case series by Hansen, Sarah, Alduaij, Waleed, Biggs, Catherine M., Belga, Sara, Luecke, Kai, Merkeley, Hayley, Chen, Luke Y. C.

“…Introduction Hemophagocytic lymphohistiocytosis (HLH) is a cytokine storm syndrome associated with mortality rates of up to 88%. Standard therapy with…”
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Extreme hyperferritinaemia, soluble interleukin‐2 receptor, and haemophagocytic lymphohistiocytosis by Chen, Luke Y. C., Hayden, Anna, Mattman, Andre

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Amelioration of COVID‐19‐related cytokine storm syndrome: parallels to chimeric antigen receptor‐T cell cytokine release syndrome by Hoiland, Ryan L., Stukas, Sophie, Cooper, Jennifer, Thiara, Sonny, Chen, Luke Y. C., Biggs, Catherine M., Hay, Kevin, Lee, Agnes Y. Y., Shojania, Kamran, Abdulla, Alym, Wellington, Cheryl L., Sekhon, Mypinder S.

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Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study by Anderson, Deverick J, Dr, Chen, Luke F, MBBS, Weber, David J, Prof, Moehring, Rebekah W, MD, Lewis, Sarah S, MD, Triplett, Patricia F, MD, Blocker, Michael, MD, Becherer, Paul, MD, Schwab, J Conrad, MD, Knelson, Lauren P, MSPH, Lokhnygina, Yuliya, PhD, Rutala, William A, PhD, Kanamori, Hajime, MD, Gergen, Maria F, MT ASCP, Sexton, Daniel J, Prof

“…Summary Background Patients admitted to hospital can acquire multidrug-resistant organisms and Clostridium difficile from inadequately disinfected…”
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Goodbye etoposide? Taking the leap to ruxolitinib in haemophagocytic lymphohistiocytosis by Merrill, Samuel A, Spaner, Caroline, Chen, Luke Y C

“…Fang et al. report a retrospective analysis of paediatric patients with haemophagocytic lymphohistiocytosis (HLH) associated with autoimmune/autoinflammatory…”
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Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome: fevers, myalgia, arthralgia, auricular chondritis, and erythema nodosum by Dehghan, Natasha, Marcon, Krista M, Sedlic, Tony, Beck, David B, Dutz, Jan P, Chen, Luke Y C

“…After 3 years of follow-up, repeated blood tests showed an increasing macrocytosis and persistent cytopenias: the patient's white blood cell count was 6 × 109…”
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Metastatic seminoma masquerading as sarcoidosis by Shopsowitz, Kevin E, Wang, Xiu Qing, Soleimani, Maryam, Hudoba, Monika, Chen, Luke Y C, McGinnis, Eric

“…Blood tests showed hypercalcaemia (2·73 mmol/L; normal 2·10–2·60) and elevated angiotensin converting enzyme (139·4 U/L; normal <79·1) and creatinine (224…”
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Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH by Hayden, Anna, Lin, Molly, Park, Sujin, Pudek, Morris, Schneider, Marion, Jordan, Michael B., Mattman, Andre, Chen, Luke Y.C.

“…Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published data on…”
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Mass spectrometry in IgG4-related disease diagnosis by Onwuka, Daniel C., Chen, Luke Y. C., Zhan, Shing H., Seidman, Michael A., Cartagena, Liliana, Killow, Veronika, Abou-tak, Hosam, Mattman, Andre, Carruthers, Mollie N.

“…We compared liquid chromatography tandem mass spectrometry (LC–MS/MS) against Binding Site immunonephelometry (BSIN) with regards to these methods’ abilities…”
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