Search Results - "Chen, Liang‐An"
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1
Palladium‐Catalyzed Regiodivergent Synthesis of 1,3‐Dienyl and Allyl Esters from Propargyl Esters
Published in Angewandte Chemie International Edition (07-06-2022)“…Catalyst‐controlled regiodivergent catalysis is a vital chemical tool that allows efficient access to large collections of structurally diverse molecules from…”
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2
Asymmetric Catalysis Mediated by the Ligand Sphere of Octahedral Chiral-at-Metal Complexes
Published in Angewandte Chemie International Edition (06-10-2014)“…Due to the relationship between structure and function in chemistry, access to novel chemical structures ultimately drives the discovery of novel chemical…”
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3
Directed Asymmetric Nickel‐Catalyzed Reductive 1,2‐Diarylation of Electronically Unactivated Alkenes
Published in Angewandte Chemie International Edition (20-03-2023)“…Transition‐metal catalyzed intermolecular 1,2‐diarylation of electronically unactivated alkenes has emerged as an extensive research topic in organic…”
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4
Nickel‐Catalyzed Arylboration of Alkenylarenes: Synthesis of Boron‐Substituted Quaternary Carbons and Regiodivergent Reactions
Published in Angewandte Chemie International Edition (05-08-2019)“…A method for the construction of boron‐substituted quaternary carbons or diarylquaternary carbons by arylboration of highly substituted alkenylarenes is…”
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5
Enantioselective Ni‐Catalyzed Three‐Component Dicarbofunctionalization of Alkenes
Published in ChemCatChem (22-09-2023)“…Asymmetric multicomponent reactions are considered as efficient protocols for constructing complex chiral molecules because of their step‐ and atom‐economy…”
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6
Manganese‐Catalyzed Redox‐Neutral Thiolation of Alkyl Halides with Thioformates
Published in Angewandte Chemie International Edition (14-08-2023)“…Transition metal‐catalyzed C−S cross‐coupling has emerged as an important strategy to furnish thioethers; however, the dominant utilization of noble metal…”
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7
Asymmetric photoredox transition-metal catalysis activated by visible light
Published in Nature (London) (06-11-2014)“…A chiral iridium complex serves as a sensitizer for photoredox catalysis and at the same time provides very effective asymmetric induction for the…”
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8
Prevention and management of lung cancer in China
Published in Cancer (01-09-2015)“…Lung cancer is the leading cause of cancer‐related death worldwide. In China, the incidence of lung cancer has grown rapidly, resulting in a large social and…”
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9
Transition Metal‐Catalyzed Synthesis of 1,2,3,4‐Tetrasubstituted 1,3‐Dienes from Propargylic Esters
Published in ChemCatChem (22-07-2024)“…Transition metal‐catalyzed synthesis of propargylic esters has been widely investigated, offering distinctive opportunities to build 1,3‐diene skeletons…”
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10
Chiral-at-Metal Octahedral Iridium Catalyst for the Asymmetric Construction of an All-Carbon Quaternary Stereocenter
Published in Angewandte Chemie International Edition (23-12-2013)“…Metal‐templated organocatalysis: The enantioselective formation of an all‐carbon quaternary stereocenter is catalyzed by the ligand sphere of an inert…”
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11
Asymmetric Lewis acid catalysis directed by octahedral rhodium centrochirality
Published in Chemical science (Cambridge) (01-01-2015)“…A rhodium-based asymmetric catalyst is introduced which derives its optical activity from octahedral centrochirality. Besides providing the exclusive source of…”
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12
Pd‐Catalyzed Dienylation of Propargylic Esters Enabling Highly Stereoselective Synthesis of Danishefsky‐Type Trisubstituted Dienes
Published in Chinese journal of chemistry (01-09-2024)“…Comprehensive Summary The stereochemical synthesis of highly substituted Danishefsky‐type dienes remains unsolved in organic chemistry. We describe a simple…”
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13
Stereoselective synthesis of substituted 1,3-dienes from propargylic esters: electrophilic-metal or redox catalysis?
Published in Science China. Chemistry (01-05-2024)“…1,3-Diene architectures are not only widely present in natural products, pharmaceuticals, and functional organic materials but also serve as versatile building…”
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14
Incidence, clinical characteristics, and outcomes of nosocomial Enterococcus spp. bloodstream infections in a tertiary-care hospital in Beijing, China: a four-year retrospective study
Published in Antimicrobial resistance & infection control (04-07-2017)“…spp. are the common cause of nosocomial bloodstream infections (BSIs) with high morbidity and mortality. The purpose of this study was to characterize the…”
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15
Perspectives on Biologically Active Camptothecin Derivatives
Published in Medicinal research reviews (01-07-2015)“…Camptothecins (CPTs) are cytotoxic natural alkaloids that specifically target DNA topoisomerase I. Research on CPTs has undergone a significant evolution from…”
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16
LiBr‐Mediated Cross‐Coupling towards α‐Trifluoromethylamines
Published in Asian journal of organic chemistry (01-08-2023)“…A LiBr‐mediated cross‐coupling reaction between organozinc reagents and α‐chloro trifluoromethyl amines for modular access to α‐trifluoromethyl amines is…”
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17
Synthesis, herbicidal activity and soil degradation of novel 5‐substituted sulfonylureas as AHAS inhibitors
Published in Pest management science (01-12-2022)“…BACKGROUND Chlorsulfuron, metsulfuron‐methyl and ethametsulfuron can damage sensitive crops in rotation pattern as a result of their long persistence in soil…”
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18
Evolution of an Efficient and Scalable Nine-Step (Longest Linear Sequence) Synthesis of Zincophorin Methyl Ester
Published in Journal of the American Chemical Society (29-03-2017)“…Because of both their synthetically challenging and stereochemically complex structures and their wide range of often clinically relevant biological…”
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19
Computed tomography-based radiomics improves non-invasive diagnosis of Pneumocystis jirovecii pneumonia in non-HIV patients: a retrospective study
Published in BMC pulmonary medicine (02-01-2024)“…Pneumocystis jirovecii pneumonia (PCP) could be fatal to patients without human immunodeficiency virus (HIV) infection. Current diagnostic methods are either…”
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20
Lung cancer treatment in the era of immunotherapy
Published in Chinese medical journal (20-10-2020)“…The updated data of the CheckMate 017/CheckMate 057 studies published at the 2019 World Conference on Lung Cancer showed that the 5-year survival rate of…”
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