Search Results - "Chen, LY"

Common VKORC1 and GGCX polymorphisms associated with warfarin dose by Wadelius, M, Chen, L Y, Downes, K, Ghori, J, Hunt, S, Eriksson, N, Wallerman, O, Melhus, H, Wadelius, C, Bentley, D, Deloukas, P

“…We report a novel combination of factors that explains almost 60% of variable response to warfarin. Warfarin is a widely used anticoagulant, which acts through…”
Get full text

Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist by Huang, P, Kehner, G B, Cowan, A, Liu-Chen, L Y

“…Buprenorphine (BUP) is an oripavine analgesic that is beneficial in the maintenance treatment of opiate-dependent individuals. Although BUP has been studied…”
Get more information

Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization by Szabo, Imre, Wetzel, Michele A., Zhang, Ning, Steele, Amber D., Kaminsky, David E., Chen, Chongguang, Liu‐Chen, Lee‐Yuan, Bednar, Filip, Henderson, Earl E., Howard, O. M. Zack, Oppenheim, Joost J., Rogers, Thomas J.

“…The opiates are well‐established immunomodulatory factors, and recent evidence suggests that μ‐ and δ‐opioid receptor ligands alter chemokine‐driven…”
Get full text

Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit by Feng, Pu, Rahim, Rahil T., Cowan, Alan, Liu-Chen, Lee-Yuan, Peng, Xiaohui, Gaughan, John, Meissler, Joseph J., Adler, Martin W., Eisenstein, Toby K.

“…Our laboratory has shown previously that subcutaneously implanted, slow-release morphine pellets markedly enhanced susceptibility to oral infection with…”
Get full text

Regulation of the regenerative activity of dental pulp stem cells from exfoliated deciduous teeth (SHED) of children by TGF-β1 is associated with ALK5/Smad2, TAK1, p38 and MEK/ERK signaling by Chang, Hsiao-Hua, Chen, Il-Ly, Wang, Yin-Lin, Chang, Mei-Chi, Tsai, Yi-Ling, Lan, Wen-Chien, Wang, Tong-Mei, Yeung, Sin-Yuet, Jeng, Jiiang-Huei

“…Transforming growth factor-β1 (TGF-β1) regulates wound healing/regeneration and aging processes. Dental pulp stem cells from human exfoliated deciduous teeth…”
Get full text

Corrosion and passivation behavior of laser powder bed fusion produced Ti-6Al-4V in static/dynamic NaCl solutions with different concentrations by Qin, P., Chen, L.Y., Liu, Y.J., Jia, Z., Liang, S.X., Zhao, C.H., Sun, H., Zhang, L.C.

“…•SLMed Ti6Al4V was tested in static/dynamic NaCl solutions with different concentrations.•The formed oxide film on SLMed Ti-6Al-4V includes TiO2, Ti2O3 and…”
Get full text

Chitosan/ β-lactoglobulin core–shell nanoparticles as nutraceutical carriers by Chen, Lingyun, Subirade, Muriel

“…Chitosan (CS)/ β-lactoglobulin ( βlg) core–shell nanoparticles (CS- βlg nanoparticle) were successfully prepared with the aim of developing a biocompatible…”
Get full text

Food protein-based materials as nutraceutical delivery systems by Chen, Lingyun, Remondetto, Gabriel E., Subirade, Muriel

“…Incorporation of bioactive compounds–such as vitamins, probiotics, bioactive peptides, and antioxidants etc.–into food systems provide a simple way to develop…”
Get full text

Regulatory effects of dexamethasone on NK and T cell immunity by Chen, Liying, Jondal, Mikael, Yakimchuk, Konstantin

“…Glucocorticoids (GCs) act via the intracellular glucocorticoid receptor (GR), which can regulate the expression of target genes. With regard to the immune…”
Get full text

Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration by Rivard, Léna, Friberg, Leif, Conen, David, Healey, Jeffrey S., Berge, Trygve, Boriani, Giuseppe, Brandes, Axel, Calkins, Hugh, Camm, A. John, Yee Chen, Lin, Lluis Clua Espuny, Josep, Collins, Ronan, Connolly, Stuart, Dagres, Nikolaos, Elkind, Mitchell S.V., Engdahl, Johan, Field, Thalia S., Gersh, Bernard J., Glotzer, Taya V., Hankey, Graeme J., Harbison, Joseph A., Georg Haeusler, Karl, Hills, Mellanie T., Johnson, Linda S.B., Joung, Boyoung, Khairy, Paul, Kirchhof, Paulus, Krieger, Derk, Lip, Gregory Y.H., Løchen, Maja-Lisa, Madhavan, Malini, Mairesse, Georges H., Montaner, Joan, Ntaios, George, Quinn, Terence J., Rienstra, Michiel, Rosenqvist, Mårten, Sandhu, Roopinder K., Smyth, Breda, Schnabel, Renate B., Stavrakis, Stavros, Themistoclakis, Sakis, Van Gelder, Isabelle C., Wang, Ji-Guang, Freedman, Ben

“…Growing evidence suggests a consistent association between atrial fibrillation (AF) and cognitive impairment and dementia that is independent of clinical…”
Get full text

Anisotropic response of Ti-6Al-4V alloy fabricated by 3D printing selective laser melting by Chen, L.Y., Huang, J.C., Lin, C.H., Pan, C.T., Chen, S.Y., Yang, T.L., Lin, D.Y., Lin, H.K., Jang, J.S.C.

“…The 3D printed bulk samples fabricated by selective laser melting (SLM) of the additive manufacturing technique are usually considered to be 3D isotropic in…”
Get full text

Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome by Dziekan, Jerzy Michal, Wirjanata, Grennady, Dai, Lingyun, Go, Ka Diam, Yu, Han, Lim, Yan Ting, Chen, Liyan, Wang, Loo Chien, Puspita, Brenda, Prabhu, Nayana, Sobota, Radoslaw M., Nordlund, Pär, Bozdech, Zbynek

“…Despite decades of research, little is known about the cellular targets and the mode of action of the vast majority of antimalarial drugs. We recently…”
Get full text

A genetics-led approach defines the drug target landscape of 30 immune-related traits by Fang, Hai, De Wolf, Hans, Knezevic, Bogdan, Burnham, Katie L., Osgood, Julie, Sanniti, Anna, Lledó Lara, Alicia, Kasela, Silva, De Cesco, Stephane, Wegner, Jörg K., Handunnetthi, Lahiru, McCann, Fiona E., Chen, Liye, Sekine, Takuya, Brennan, Paul E., Marsden, Brian D., Damerell, David, O’Callaghan, Chris A., Bountra, Chas, Bowness, Paul, Sundström, Yvonne, Milani, Lili, Berg, Louise, Göhlmann, Hinrich W., Peeters, Pieter J., Fairfax, Benjamin P., Sundström, Michael, Knight, Julian C.

“…Most candidate drugs currently fail later-stage clinical trials, largely due to poor prediction of efficacy on early target selection 1 . Drug targets with…”
Get full text

Possible mechanism of hypothermia induced by intracerebroventricular injection of orphanin FQ/nociceptin by Chen, Xiaohong, McClatchy, Daniel B, Geller, Ellen B, Liu-Chen, Lee-Yuan, Tallarida, Ronald J, Adler, Martin W

“…Orphanin/nociceptin (OFQ/N), a 17-amino-acid peptide, is an endogenous peptide, the receptor for which is similar to μ-, δ- and κ-opioid receptors (∼65%…”
Get full text

Improved trade-off between strength and plasticity in titanium based metastable beta type Ti-Zr-Fe-Sn alloys by Rabadia, C.D., Liu, Y.J., Zhao, C.H., Wang, J.C., Jawed, S.F., Wang, L.Q., Chen, L.Y., Sun, H., Zhang, L.C.

“…An impressive strengthening ability of Laves phases is favorable to develop titanium alloys with an improved trade-off between strength and plasticity…”
Get full text

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas by Georgiou, Konstantinos, Chen, Longyun, Berglund, Mattias, Ren, Weicheng, de Miranda, Noel F.C.C., Lisboa, Susana, Fangazio, Marco, Zhu, Shida, Hou, Yong, Wu, Kui, Fang, Wenfeng, Wang, Xianhuo, Meng, Bin, Zhang, Li, Zeng, Yixin, Bhagat, Govind, Nordenskjöld, Magnus, Sundström, Christer, Enblad, Gunilla, Dalla-Favera, Riccardo, Zhang, Huilai, Teixeira, Manuel R., Pasqualucci, Laura, Peng, Roujun, Pan-Hammarström, Qiang

“…Diffuse large B-cell lymphoma (DLBCL) is one of the most common and aggressive types of B-cell lymphoma. Deregulation of proto-oncogene expression after a…”
Get full text

Microstructure and mechanical properties of open-cell porous Ti-6Al-4V fabricated by selective laser melting by Chen, S.Y., Huang, J.C., Pan, C.T., Lin, C.H., Yang, T.L., Huang, Y.S., Ou, C.H., Chen, L.Y., Lin, D.Y., Lin, H.K., Li, T.H., Jang, J.S.C., Yang, C.C.

“…The open-cell porous Ti-6Al-4V structure, intended to be applied as replacement for human cortical and cancellous bone, are fabricated by selective laser…”
Get full text

B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity by Qian, Jason, Wang, Qiao, Dose, Marei, Pruett, Nathanael, Kieffer-Kwon, Kyong-Rim, Resch, Wolfgang, Liang, Genqing, Tang, Zhonghui, Mathé, Ewy, Benner, Christopher, Dubois, Wendy, Nelson, Steevenson, Vian, Laura, Oliveira, Thiago Y., Jankovic, Mila, Hakim, Ofir, Gazumyan, Anna, Pavri, Rushad, Awasthi, Parirokh, Song, Bin, Liu, Geng, Chen, Longyun, Zhu, Shida, Feigenbaum, Lionel, Staudt, Louis, Murre, Cornelis, Ruan, Yijun, Robbiani, Davide F., Pan-Hammarström, Qiang, Nussenzweig, Michel C., Casellas, Rafael

“…The antibody gene mutator activation-induced cytidine deaminase (AID) promiscuously damages oncogenes, leading to chromosomal translocations and tumorigenesis…”
Get full text

Genetic landscape of hepatitis B virus–associated diffuse large B-cell lymphoma by Ren, Weicheng, Ye, Xiaofei, Su, Hong, Li, Wei, Liu, Dongbing, Pirmoradian, Mohammad, Wang, Xianhuo, Zhang, Bo, Zhang, Qiang, Chen, Longyun, Nie, Man, Liu, Yao, Meng, Bin, Huang, Huiqiang, Jiang, Wenqi, Zeng, Yixin, Li, Wenyu, Wu, Kui, Hou, Yong, Wiman, Klas G., Li, Zhiming, Zhang, Huilai, Peng, Roujun, Zhu, Shida, Pan-Hammarström, Qiang

“…Hepatitis B virus (HBV) infection is endemic in some parts of Asia, Africa, and South America and remains to be a significant public health problem in these…”
Get full text

Effect of annealing treatment on the microstructure and mechanical properties of a duplex Zr-2.5Nb alloy by Zhang, M., Li, Y.N., Zhang, F.C., Wang, X.B., Chen, L.Y., Yang, Z.N.

“…The microstructural evolution and mechanical properties of a duplex Zr-2.5Nb alloy annealed at different temperatures have been studied in detail. The results…”
Get full text