Search Results - "Chen, K y"

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products by Chen, David Y.-K., Youn, So Won

“…The recent advent of transition‐metal mediated CH activation is revolutionizing the synthetic field and gradually infusing a “CH activation mind‐set” in both…”
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Recent advances in the total synthesis of cyclopropane-containing natural products by Chen, David Y-K, Pouwer, Rebecca H, Richard, Jean-Alexandre

“…In this tutorial review, recent advances in the synthesis of cyclopropane-containing natural products are discussed, highlighting the application of novel…”
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The role of regional anaesthesia and multimodal analgesia in the prevention of chronic postoperative pain: a narrative review by Chen, Y.‐Y. K., Boden, K. A., Schreiber, K. L.

“…Summary Effective prevention of chronic postoperative pain is an important clinical goal, informed by a growing body of studies. Peri‐operative regional…”
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Pressure-induced monotonic enhancement of Tc to over 30 K in superconducting Pr0.82Sr0.18NiO2 thin films by Wang, N. N., Yang, M. W., Yang, Z., Chen, K. Y., Zhang, H., Zhang, Q. H., Zhu, Z. H., Uwatoko, Y., Gu, L., Dong, X. L., Sun, J. P., Jin, K. J., Cheng, J.-G.

“…The successful synthesis of superconducting infinite-layer nickelate thin films with the highest T c  ≈ 15 K has ignited great enthusiasm for this material…”
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The Chemistry of the Polycyclic Polyprenylated Acylphloroglucinols by Richard, Jean-Alexandre, Pouwer, Rebecca H., Chen, David Y.-K.

“…With their fascinating biological profiles and stunningly complex molecular architectures, the polycyclic polyprenylated acylphloroglucinols (PPAPs) have long…”
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A Local‐Desymmetrization‐Based Divergent Synthesis of Quinine and Quinidine by Lee, Jaehoo, Chen, David Y.‐K.

“…Herein we report a novel synthetic entry to the legendary quinuclidine natural products quinine and quinidine. The developed strategy is based on the use of a…”
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Virus shedding dynamics in asymptomatic and mildly symptomatic patients infected with SARS-CoV-2 by Li, W., Su, Y.-Y., Zhi, S.-S., Huang, J., Zhuang, C.-L., Bai, W.-Z., Wan, Y., Meng, X.-R., Zhang, L., Zhou, Y.-B., Luo, Y.-Y., Ge, S.-X., Chen, Y.-K., Ma, Y.

“…Asymptomatic patients, together with those with mild symptoms of coronavirus disease 2019 (COVID-19), may play an important role in severe acute respiratory…”
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Cold-induced thermogenesis in humans by Brychta, R J, Chen, K Y

“…A basic property of endothermic thermoregulation is the ability to generate heat by increasing metabolism in response to cold ambient temperatures to maintain…”
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Measuring energy expenditure in clinical populations: rewards and challenges by Psota, T, Chen, K Y

“…The measurement of energy expenditure (EE) is recommended as an important component of comprehensive clinical nutrition assessments in patients with altered…”
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A Desymmetrization‐Based Total Synthesis of Reserpine by Park, Jisook, Chen, David Y.‐K.

“…Reported herein is a desymmetrization‐based synthetic approach to the fused polycyclic indole alkaloid reserpine. The centerpiece of the developed strategy…”
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Pressured-induced superconducting phase with large upper critical field and concomitant enhancement of antiferromagnetic transition in EuTe2 by Yang, P. T., Liu, Z. Y., Chen, K. Y., Liu, X. L., Zhang, X., Yu, Z. H., Zhang, H., Sun, J. P., Uwatoko, Y., Dong, X. L., Jiang, K., Hu, J. P., Guo, Y. F., Wang, B. S., Cheng, J.-G.

“…We report an unusual pressure-induced superconducting state that coexists with an antiferromagnetic ordering of Eu 2+ moments and shows a large upper critical…”
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Asymmetric Total Syntheses of Communesin F and a Putative Member of the Communesin Family by Park, Jisook, Jean, Alexandre, Chen, David Y.‐K.

“…Here we report asymmetric total syntheses of communesin F and a putative member of the communesin family of bis‐aminal alkaloid natural products. The…”
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Dysregulation of interleukin 5 expression in familial eosinophilia by Prakash Babu, S., Chen, Y.‐Y. K., Bonne‐Annee, S., Yang, J., Maric, I., Myers, T. G., Nutman, T. B., Klion, A. D.

“…Background Familial eosinophilia (FE) is a rare autosomal dominant inherited disorder characterized by the presence of lifelong peripheral eosinophilia…”
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Total Synthesis and Biological Evaluation of the Resveratrol-Derived Polyphenol Natural Products Hopeanol and Hopeahainol A by Nicolaou, K. C, Kang, Qiang, Wu, T. Robert, Lim, Chek Shik, Chen, David Y.-K

“…The total synthesis and biological evaluation of the resveratrol-derived natural products hopeanol (2) and hopeahainol A (3) in their racemic and antipodal…”
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Stereo‐Controlled Synthesis of Vicinal Tertiary Carbinols: Application in the Synthesis of a Diol Substructure of Zaragozic Acid, Pactamycin and Ryanodol by Kim, Byungjoo, Puthukanoori, Ravi Kumar, Martha, Bhikshapathi, Reddy Muthyala, Nagarjuna, Thota, Srinivas, Thummala, Venkatesham, Rao Paraselli, Bheema, Chen, David Y.‐K.

“…Abstract A novel and flexible approach for the stereo‐controlled synthesis of vicinal tertiary carbinols is reported. The developed strategy featured a highly…”
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Total Synthesis of Englerin A by Nicolaou, K. C, Kang, Qiang, Ng, Sin Yee, Chen, David Y.-K

“…Total synthesis of englerin A, a recently reported sesquiterpenoid exhibiting potent and selective growth inhibition against renal cancer cell lines, has been…”
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Total Synthesis of Strychnine by Lee, Geun Seok, Namkoong, Gil, Park, Jisook, Chen, David Y.‐K.

“…The total synthesis of the flagship Strychnos indole alkaloid, strychnine, has been accomplished. The developed synthetic sequence features a novel vinylogous…”
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Cancer risk in patients with Hashimoto’s thyroiditis: a nationwide cohort study by Chen, Y-K, Lin, C-L, Cheng, F T-F, Sung, F-C, Kao, C-H

“…Background: This study examined the risk of cancer in patients with Hashimoto’s thyroiditis (HT). Methods: The Taiwanese National Health Insurance Research…”
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Total Synthesis of Actinophyllic Acid by Yoshii, Yu, Tokuyama, Hidetoshi, Chen, David Y.‐K.

“…Herein we report a total synthesis of the indolohydroazocine natural product actinophyllic acid. The target molecule was retrosynthetically deconvoluted to…”
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Hyperglycemia‐related FAS gene and hsa‐let‐7b‐5p as markers of poor outcomes for ischaemic stroke by Chi, N.‐F., Chiou, H.‐Y., Chou, S.‐Y., Hu, C.‐J., Chen, K.‐Y., Chang, C.‐F., Hsieh, Y.‐C.

“…Background and purpose Hyperglycemia in acute stroke leads to poor neurological outcomes. The role of microRNA (miRNA) in hyperglycemia‐associated genes can…”
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