Search Results - "Chen, Johnny L"

Enhanced Intracellular Delivery of a Model Drug Using Microbubbles Produced by a Microfluidic Device by Dixon, Adam J, Dhanaliwala, Ali H, Chen, Johnny L, Hossack, John A

“…Abstract Focal drug delivery to a vessel wall facilitated by intravascular ultrasound and microbubbles holds promise as a potential therapy for…”
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Synthesis and Characterization of Transiently Stable Albumin-Coated Microbubbles via a Flow-Focusing Microfluidic Device by Chen, Johnny L, Dhanaliwala, Ali H, Dixon, Adam J, Klibanov, Alexander L, Hossack, John A

“…Abstract We describe a method for synthesizing albumin-shelled, large-diameter (>10 μm), transiently stable microbubbles using a flow-focusing microfluidic…”
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Liquid flooded flow-focusing microfluidic device for in situ generation of monodisperse microbubbles by Dhanaliwala, Ali H., Chen, Johnny L., Wang, Shiying, Hossack, John A.

“…Current microbubble-based ultrasound contrast agents are administered intravenously resulting in large losses of contrast agent, systemic distribution, and…”
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In vivo imaging of microfluidic-produced microbubbles by Dhanaliwala, Ali H., Dixon, Adam J., Lin, Dan, Chen, Johnny L., Klibanov, Alexander L., Hossack, John A.

“…Microfluidics-based production of stable microbubbles for ultrasound contrast enhancement or drug/gene delivery allows for precise control over microbubble…”
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Production rate and diameter analysis of spherical monodisperse microbubbles from two-dimensional, expanding-nozzle flow-focusing microfluidic devices by Wang, Shiying, Dhanaliwala, Ali H., Chen, Johnny L., Hossack, John A.

“…Flow-focusing microfluidic devices (FFMDs) can produce microbubbles (MBs) with precisely controlled diameters and a narrow size distribution. In this paper,…”
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Microbubble-mediated intravascular ultrasound imaging and drug delivery by Dixon, Adam J., Kilroy, Joseph P., Dhanaliwala, Ali H., Chen, Johnny L., Phillips, Linsey C., Ragosta, Michael, Klibanov, Alexander L., Wamhoff, Brian R., Hossack, John A.

“…Intravascular ultrasound (IVUS) provides radiation-free, real-time imaging and assessment of atherosclerotic disease in terms of anatomical, functional, and…”
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Estimation of shipping noise from sparse measurements via generative adversarial networks by Chen, Johnny L., Summers, Jason E.

“…There is growing interest in prediction of anthropogenic noise levels in the ocean. Evidence suggests that sources of ambient noise such as shipping traffic…”
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Deep convolutional neural networks for semi-supervised learning from synthetic aperture sonar (SAS) images by Chen, Johnny L., Summers, Jason E.

“…Advancements in deep neural networks for computer-vision tasks have the potential to improve automatic target recognition (ATR) in synthetic aperture sonar…”
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Deep neural networks for learning classification features and generative models from synthetic aperture sonar big data by Chen, Johnny L., Summers, Jason E.

“…Autonomous synthetic aperture sonar (SAS) imaging by unmanned underwater vehicles (UUVs) provides an abundance of high-resolution acoustic imagery useful for…”
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Deep learning for underwater noise classification by Chen, Johnny L., Nguyen, Sarah, Trader, Jason M., Moore, Andrew, Summers, Jason E.

“…Deep-learning models have surpassed many computer-vision benchmarks and groups such as Google have begun to investigate similar methods for understanding…”
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Deep reinforcement learning for cognitive sonar by Summers, Jason E., Trader, Jason M., Gaumond, Charles F., Chen, Johnny L.

“…Current developments in cognitive sonar have leveraged explicit semantic representations such as ontologies to develop cognitive agents that enable adaptation…”
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Acoustically active red blood cell carriers for ultrasound-triggered drug delivery with photoacoustic tracking by Chen, Johnny L., Dhanaliwala, Ali H., Dixon, Adam J., Farry, Justin M., Hossack, John A., Klibanov, Alexander L.

“…As a biological alternative to conventional microbubble and droplet based ultrasound therapeutic agents, red blood cell (RBC) carriers have a potentially…”
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Model drug delivery by transiently stable microbubbles produced by a microfluidic device by Dixon, Adam J., Dhanaliwala, Ali H., Chen, Johnny L., Hossack, John A.

“…Ultrasound-mediated drug delivery using intravascular ultrasound (IVUS) and microbubbles holds promise as a potential therapy for diseases of the vasculature…”
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Synthesis of albumin microbubbles using a microfluidic device for real-time imaging and therapeutics by Chen, Johnny L., Dhanaliwala, Ali H., Dixon, Adam J., Klibanov, Alexander L., Hossack, John A.

“…A method for producing monodisperse albumin stabilized microbubbles (MBs) using a flow-focusing microfluidic device (FFMD) is introduced. This method allows…”
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Ensemble Forecasting of Tropical Cyclone Motion Using a Baroclinic Model by 周霞琼 陈仲良

“…The purpose of this study is to investigate the effectiveness of two different ensemble forecasting （EF） techniques-the lagged-averaged forecast （LAF） and the…”
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Intravascular ultrasound-based imaging and drug delivery by Dhanaliwala, Ali H., Chen, Johnny L., Kilroy, Joseph P., Phillips, Linsey C., Dixon, Adam J., Klibanov, Alexander L., Wamhoff, Brian R., Hossack, John A.

“…An ideal solution for the diagnosis and treatment of a vascular disease must involve high-resolution imaging, quantitative characterization of the lesion, and…”
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In vivo acoustic contrast enhancement via simultaneous production and injection of microfluidic-produced microbubbles by Dixon, Adam J., Dhanaliwala, Ali H., Dan Lin, Chen, Johnny L., Klibanov, Alexander L., Hossack, John A.

“…Microbubble production by microfluidic devices for ultrasound contrast enhancement allows for precise control over microbubble diameter but at the cost of low…”
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Parallel output, liquid flooded flow-focusing microfluidic device for generating monodisperse microbubbles within a catheter by Chen, J. L., Dhanaliwala, A. H., Shiying Wang, Hossack, J. A.

“…A new method for supplying the liquid phase to a flow focusing microfluidic device (FFMD), designed for the production of monodisperse microbubbles (MBs), is…”
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Optimal microbubble production rate from a flow-focusing microfluidic device as a function of nozzle size, gas pressure, and liquid flow rate by Shiying Wang, Dhanaliwala, A. H., Chen, J. L., Hossack, J. A.

“…Previous studies have shown that flow-focusing microfluidic devices (FFMDs) produce monodisperse microbubbles with tunable diameters in a continuous process…”
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