Search Results - "Chen, Jing‐Hsien"

Protocatechuic acid inhibits cancer cell metastasis involving the down‐regulation of Ras/Akt/NF‐κB pathway and MMP‐2 production by targeting RhoB activation by Lin, Hui‐Hsuan, Chen, Jing‐Hsien, Chou, Fen‐Pi, Wang, Chau‐Jong

“…BACKGROUND AND PURPOSE Protocatechuic acid (PCA) is plentiful in edible fruits and vegetables and is thus one anti‐oxidative component of normal human diets…”
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Lotus Seedpod Extracts Reduced Lipid Accumulation and Lipotoxicity in Hepatocytes by Liu, Yen-Tze, Lai, Yen-Hsun, Lin, Hui-Hsuan, Chen, Jing-Hsien

“…Non-alcoholic fatty liver disease (NAFLD) is closely associated with metabolic disorders, including hepatic lipid accumulation and lipotoxicity. Plant-derived…”
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Therapeutic Effect of Desmodium caudatum Extracts on Alleviating Diabetic Nephropathy Mice by Lin, Hui-Hsuan, Tseng, Chiao-Yun, Yu, Pei-Rong, Ho, Hsiang-Yu, Hsu, Cheng-Chin, Chen, Jing-Hsien

“…Desmodium caudatum extracts (DCE) were investigated for their potential therapeutic effects on diabetic nephropathy (DN). In our study, the high-fat diet (HFD)…”
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Anti-Hypertensive Effect of Solanum muricatum Aiton Leaf Extract In Vivo and In Vitro by Lin, Hui-Hsuan, Tsai, Chia-Lin, Tseng, Chiao-Yun, Yu, Pei-Rong, Chiu, Pei-Yu, Hsu, Cheng-Chin, Chen, Jing-Hsien

“…Hypertension is a global health problem and leads to cardiovascular disease and renal injury. Solanum muricatum Aiton leaf extract, rich in flavonoids, is…”
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Anti-Melanogenesis Effects of Lotus Seedpod In Vitro and In Vivo by Hsu, Jen-Ying, Lin, Hui-Hsuan, Li, Ting-Shuan, Tseng, Chaio-Yun, Wong, Yueching, Chen, Jing-Hsien

“…Melanogenesis has many important physiological functions. However, abnormal melanin production causes various pigmentation disorders. Melanin synthesis is…”
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Anti‐prostate cancer potential of gossypetin via inducing apoptotic and autophagic cell death by Lee, Ming‐Shih, Tsai, Chia‐Wen, Wang, Chi‐Ping, Chen, Jing‐Hsien, Lin, Hui‐Hsuan

“…Gossypetin (GTIN), a naturally occurring hexahydroxy flavone, has been shown to possess antimutagenic, antioxidant, antimicrobial, and antiatherosclerotic…”
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Chemopreventive properties and molecular mechanisms of the bioactive compounds in Hibiscus sabdariffa Linne by Lin, Hui-Hsuan, Chen, Jing-Hsien, Wang, Chau-Jong

“…Hibiscus sabdariffa Linne is a traditional Chinese rose tea and has been effectively used in folk medicines for treatment of hypertension, inflammatory…”
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Carnosic Acid Prevents 6‑Hydroxydopamine-Induced Cell Death in SH-SY5Y Cells via Mediation of Glutathione Synthesis by Chen, Jing-Hsien, Ou, Hsin-Ping, Lin, Chia-Yuan, Lin, Fung-Ju, Wu, Chi-Rei, Chang, Shu-Wei, Tsai, Chia-Wen

“…Understanding the neuroprotective effects of the rosemary phenolic diterpene carnosic acid (CA) has attracted increasing attention. We explored the mechanism…”
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In Vivo Protective Effects of Diosgenin against Doxorubicin-Induced Cardiotoxicity by Chen, Chih-Tai, Wang, Zhi-Hong, Hsu, Cheng-Chin, Lin, Hui-Hsuan, Chen, Jing-Hsien

“…Doxorubicin (DOX) induces oxidative stress leading to cardiotoxicity. Diosgenin, a steroidal saponin of Dioscorea opposita, has been reported to have…”
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Aqueous Extract of Pepino ( Solanum muriactum Ait) Leaves Ameliorate Lipid Accumulation and Oxidative Stress in Alcoholic Fatty Liver Disease by Hsu, Jen-Ying, Lin, Hui-Hsuan, Hsu, Cheng-Chin, Chen, Bing-Chen, Chen, Jing-Hsien

“…Chronic alcohol intake leads to alcoholic fatty liver. The pathogenesis of alcoholic fatty liver is related to abnormal lipid accumulation, oxidative stress,…”
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Apoptotic effect of 3,4‐dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation by Lin, Hui‐Hsuan, Chen, Jing‐Hsien, Huang, Chi‐Chou, Wang, Chau‐Jong

“…3,4‐Dihydroxybenzoic acid (protocatechuic acid, PCA) is discussed to represent antioxidative food components in a human diet rich in fruits and vegetables, and…”
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Autophagic effects of Hibiscus sabdariffa leaf polyphenols and epicatechin gallate (ECG) against oxidized LDL-induced injury of human endothelial cells by Chen, Jing-Hsien, Lee, Ming-Shih, Wang, Chi-Ping, Hsu, Cheng-Chin, Lin, Hui-Hsuan

“…Purpose Oxidized low-density lipoprotein (ox-LDL) contributes to the pathogenesis of atherosclerosis by promoting vascular endothelial cell injury. Hibiscus…”
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Hibiscus sabdariffa Leaf Polyphenolic Extract Induces Human Melanoma Cell Death, Apoptosis, and Autophagy by Chiu, Chun-Tang, Hsuan, Shu-Wen, Lin, Hui-Hsuan, Hsu, Cheng-Chin, Chou, Fen-Pi, Chen, Jing-Hsien

“…Melanoma is the least common but most fatal form of skin cancer. Previous studies have indicated that an aqueous extract of Hibiscus sabdariffa leaves possess…”
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In Vitro and In Vivo Protective Effects of Flavonoid-Enriched Lotus Seedpod Extract on Lipopolysaccharide-Induced Hepatic Inflammation by Tseng, Hsien-Chun, Tsai, Pei-Min, Chou, Ying-Hsiang, Lee, Yueh-Chun, Lin, Hui-Hsuan, Chen, Jing-Hsien

“…Endotoxin lipopolysaccharide (LPS) plays an important role in the acceleration of hepatic inflammation. Natural medicinal plants that can prevent inflammation…”
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Anti-Atherosclerotic Effect of Hibiscus Leaf Polyphenols against Tumor Necrosis Factor-alpha-Induced Abnormal Vascular Smooth Muscle Cell Migration and Proliferation by Chou, Cheng-Chung, Wang, Chi-Ping, Chen, Jing-Hsien, Lin, Hui-Hsuan

“…The proliferation and migration of vascular smooth muscle cells (VSMCs) are major events in the development of atherosclerosis following stimulation with…”
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Aqueous extract from Pepino (Solanum muricatum Ait.) leaves ameliorated insulin resistance, hyperlipidemia, and hyperglycemia in mice with metabolic syndrome by Hsu, Jen‐Ying, Lin, Hui‐Hsuan, Wang, Zhi‐Hong, Chen, Jing‐Hsien

“…Solanum muricatum Ait. (Pepino) is a plant food commonly cultivated in the Penghu Island, Taiwan. This present study aimed to investigate the protective…”
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Carnosic Acid, a Rosemary Phenolic Compound, Induces Apoptosis Through Reactive Oxygen Species-Mediated p38 Activation in Human Neuroblastoma IMR-32 Cells by Tsai, Chia-Wen, Lin, Chia-Yuan, Lin, Hui-Hsuan, Chen, Jing-Hsien

“…Carnosic acid (CA), a rosemary phenolic compound, has been shown to display anti-cancer activity. We examined the apoptotic effect of CA in human neuroblastoma…”
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Anti-atherosclerotic potential of gossypetin via inhibiting LDL oxidation and foam cell formation by Chen, Jing-Hsien, Tsai, Chia-Wen, Wang, Chi-Ping, Lin, Hui-Hsuan

“…Gossypetin, a flavone originally isolated from Hibiscus species, has been shown to possess antioxidant, antimicrobial, and antimutagenic activities. Here, we…”
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Aqueous Extract of Pepino Leaves Ameliorates Palmitic Acid-Induced Hepatocellular Lipotoxicity via Inhibition of Endoplasmic Reticulum Stress and Apoptosis by Hsu, Jen-Ying, Lin, Hui-Hsuan, Chyau, Charng-Cherng, Wang, Zhi-Hong, Chen, Jing-Hsien

“…Saturated fatty acid is one of the important nutrients, but contributes to lipotoxicity in the liver, causing hepatic steatosis. Aqueous pepino leaf extract…”
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Anti-Atherosclerotic Effect of Gossypetin on Abnormal Vascular Smooth Muscle Cell Proliferation and Migration by Lin, Hui-Hsuan, Hsieh, Ming-Chang, Wang, Chi-Ping, Yu, Pei-Rong, Lee, Ming-Shih, Chen, Jing-Hsien

“…Gossypetin (GTIN), known as 3,5,7,8,3′,4′-hexahydroxyflavone, has been demonstrated to exert anti-atherosclerotic potential against apoptotic injury in…”
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