Search Results - "Chen, Jennifer S."

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes by Ravindra, Neal G, Alfajaro, Mia Madel, Gasque, Victor, Huston, Nicholas C, Wan, Han, Szigeti-Buck, Klara, Yasumoto, Yuki, Greaney, Allison M, Habet, Victoria, Chow, Ryan D, Chen, Jennifer S, Wei, Jin, Filler, Renata B, Wang, Bao, Wang, Guilin, Niklason, Laura E, Montgomery, Ruth R, Eisenbarth, Stephanie C, Chen, Sidi, Williams, Adam, Iwasaki, Akiko, Horvath, Tamas L, Foxman, Ellen F, Pierce, Richard W, Pyle, Anna Marie, van Dijk, David, Wilen, Craig B

“…There are currently limited Food and Drug Administration (FDA)-approved drugs and vaccines for the treatment or prevention of Coronavirus Disease 2019…”
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Nonsteroidal Anti-inflammatory Drugs Dampen the Cytokine and Antibody Response to SARS-CoV-2 Infection by Chen, Jennifer S, Alfajaro, Mia Madel, Chow, Ryan D, Wei, Jin, Filler, Renata B, Eisenbarth, Stephanie C, Wilen, Craig B

“…Identifying drugs that regulate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its symptoms has been a pressing area of…”
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A web tool for the design of prime-editing guide RNAs by Chow, Ryan D., Chen, Jennifer S., Shen, Johanna, Chen, Sidi

“…Prime editing enables diverse genomic alterations to be written into target sites without requiring double-strand breaks or donor templates. The design of…”
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Genetic determinants and epigenetic effects of pioneer-factor occupancy by Donaghey, Julie, Thakurela, Sudhir, Charlton, Jocelyn, Chen, Jennifer S., Smith, Zachary D., Gu, Hongcang, Pop, Ramona, Clement, Kendell, Stamenova, Elena K., Karnik, Rahul, Kelley, David R., Gifford, Casey A., Cacchiarelli, Davide, Rinn, John L., Gnirke, Andreas, Ziller, Michael J., Meissner, Alexander

“…Transcription factors (TFs) direct developmental transitions by binding to target DNA sequences, influencing gene expression and establishing complex…”
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Embracing a change by Chen, Jennifer S

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IL17A mRNA Staining Distinguishes Palmoplantar Psoriasis from Hyperkeratotic Palmoplantar Eczema in Diagnostic Skin Biopsies by Chen, Jennifer S., Murphy, Michael J., Singh, Katelyn, Wang, Alice, Chow, Ryan D., Kim, Sa Rang, Cohen, Jeffrey M., Ko, Christine J., Damsky, William

“…Acral dermatoses, including hyperkeratotic palmoplantar eczema (HPE), palmoplantar psoriasis (PP), and mycosis fungoides palmaris et plantaris (MFPP), can be…”
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T follicular helper cells in food allergy by Chen, Jennifer S, Lee, Donguk, Gowthaman, Uthaman

“…T follicular helper (Tfh) cells help direct the production of antibodies by B cells. In addition to promoting antibody responses to vaccination and infection,…”
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Regulation of IgE by T follicular helper cells by Gowthaman, Uthaman, Chen, Jennifer S., Eisenbarth, Stephanie C.

“…Allergies to food and environmental antigens have steeply grown to epidemic proportions. IgE antibodies are key mediators of allergic disease, including…”
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Identification of a T follicular helper cell subset that drives anaphylactic IgE by Gowthaman, Uthaman, Chen, Jennifer S, Zhang, Biyan, Flynn, William F, Lu, Yisi, Song, Wenzhi, Joseph, Julie, Gertie, Jake A, Xu, Lan, Collet, Magalie A, Grassmann, Jessica D S, Simoneau, Tregony, Chiang, David, Berin, M Cecilia, Craft, Joseph E, Weinstein, Jason S, Williams, Adam, Eisenbarth, Stephanie C

“…Cross-linking of high-affinity immunoglobulin E (IgE) results in the life-threatening allergic reaction anaphylaxis. Yet the cellular mechanisms that induce B…”
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An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2 by Tada, Takuya, Fan, Chen, Chen, Jennifer S., Kaur, Ramanjit, Stapleford, Kenneth A., Gristick, Harry, Dcosta, Belinda M., Wilen, Craig B., Nimigean, Crina M., Landau, Nathaniel R.

“…Soluble forms of angiotensin-converting enzyme 2 (ACE2) have recently been shown to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Myoclonus associated with long-term use of diltiazem by Swanoski, Michael T, Chen, Jennifer S, Monson, Mark H

“…A case of possible diltiazem-induced myoclonus in a patient receiving long-term therapy, with residual symptoms after discontinuation, is reported. A…”
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Separation of doxorubicin and doxorubicinol by cyclodextrin-modified micellar electrokinetic capillary chromatography by Eder, Angela R., Chen, Jennifer S., Arriaga, Edgar A.

“…Doxorubicinol (DOXol) is a human metabolite of the chemotherapy agent doxorubicin (DOX), and is associated with dose‐dependent cardiotoxicity and decreased…”
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Two-Factor Authentication for Type 2 Immunity by Chen, Jennifer S., Eisenbarth, Stephanie C.

“…The initiation of type 2 responses is tightly regulated. In this issue of Immunity, Sokol et al. (2018) demonstrate that CCL8 is a critical signal that…”
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Unlabeled uses of botulinum toxins: A review, part 1 by Cheng, Christine M, Chen, Jennifer S, Patel, Rosalie P

“…Efficacy and safety data regarding the unlabeled uses of botulinum toxins are reviewed, and the pharmacology, adverse effects, and characteristics of…”
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Flow cytometric identification of Tfh13 cells in mouse and human by Chen, Jennifer S., Grassmann, Jessica D.S., Gowthaman, Uthaman, Olyha, Sam J., Simoneau, Tregony, Berin, M. Cecilia, Eisenbarth, Stephanie C., Williams, Adam

“…Anaphylaxis is a life-threatening allergic reaction caused by cross-linking of high-affinity IgE antibodies on the surface of mast cells and basophils…”
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A novel microporous biomaterial vaccine platform for long-lasting antibody mediated immunity against viral infection by Mayer, Daniel P., Nelson, Mariah E., Andriyanova, Daria, Filler, Renata B., Ökten, Arya, Antao, Olivia Q., Chen, Jennifer S., Scumpia, Philip O., Weaver, Westbrook M., Wilen, Craig B., Deshayes, Stephanie, Weinstein, Jason S.

“…Current antigen delivery platforms, such as alum and nanoparticles, are not readily tunable, thus may not generate optimal adaptive immune responses. We…”
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Unlabeled uses of botulinum toxins: A review, part 2 by Cheng, Christine M, Chen, Jennifer S, Patel, Rosalie P

“…Efficacy and safety data regarding the unlabeled uses of botulinum toxins are reviewed, and the pharmacology, adverse effects, and characteristics of…”
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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection by Wei, Jin, Alfajaro, Mia Madel, DeWeirdt, Peter C., Hanna, Ruth E., Lu-Culligan, William J., Cai, Wesley L., Strine, Madison S., Zhang, Shang-Min, Graziano, Vincent R., Schmitz, Cameron O., Chen, Jennifer S., Mankowski, Madeleine C., Filler, Renata B., Ravindra, Neal G., Gasque, Victor, de Miguel, Fernando J., Patil, Ajinkya, Chen, Huacui, Oguntuyo, Kasopefoluwa Y., Abriola, Laura, Surovtseva, Yulia V., Orchard, Robert C., Lee, Benhur, Lindenbach, Brett D., Politi, Katerina, van Dijk, David, Kadoch, Cigall, Simon, Matthew D., Yan, Qin, Doench, John G., Wilen, Craig B.

“…Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may reveal novel therapeutic targets and…”
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Rules all PIs should follow by Chen, Jennifer S, Huang, Chih Ying, Lanke, Shantanu, Fernandopulle, Michael Sanjay, Ji, Yongsheng, Zhi, Yuan, Rodríguez, Sara Granado, Frommel, Andrea Y, Lukačišin, Martin, Zhang, Yida, Zdenek, Christina N, Wu, Xiao-Yu, Seenuvasaragavan, Senthilkumar, Zhuang, Yan, Bergh, Cathrine, Coulbois, Jaime, Salloum-Asfar, Salam, Cao, Bo, Davis, Katherine, Oda, Fernanda, Konstantinides, Nikos, Zhang, Liping, Agarwal, Divyansh, Rainaldi, Joseph Nicholas, Kadlec, Jan, Vekeman, Jelle, Kanigicherla, Vishal Anirudh, Oi, Kathryn, Isaacson, Kyle J, Ganji, Rakesh, Dawson-Glass, Emma

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Improving the Remediation Process for Skills-based Laboratory Courses in the Doctor of Pharmacy Curriculum by Chen, Jennifer S., Matthews, David E., Van Hooser, Jared, Knockel, Laura E., Lintner, Kim, Stoa, Morgan, Woodyard, Jamie L., Tran, Deanna

“…When students fail to meet minimum competence standards on summative pharmacy skills-based assessments, remediation can be used to ensure student readiness for…”
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