Search Results - "Chen, James J."

A heuristic approach to determine an appropriate number of topics in topic modeling by Zhao, Weizhong, Chen, James J, Perkins, Roger, Liu, Zhichao, Ge, Weigong, Ding, Yijun, Zou, Wen

“…Topic modelling is an active research field in machine learning. While mainly used to build models from unstructured textual data, it offers an effective means…”
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Text mining for identifying topics in the literatures about adolescent substance use and depression by Wang, Shi-Heng, Ding, Yijun, Zhao, Weizhong, Huang, Yung-Hsiang, Perkins, Roger, Zou, Wen, Chen, James J

“…Both adolescent substance use and adolescent depression are major public health problems, and have the tendency to co-occur. Thousands of articles on…”
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Use of data mining at the Food and Drug Administration by Duggirala, Hesha J, Tonning, Joseph M, Smith, Ella, Bright, Roselie A, Baker, John D, Ball, Robert, Bell, Carlos, Bright-Ponte, Susan J, Botsis, Taxiarchis, Bouri, Khaled, Boyer, Marc, Burkhart, Keith, Steven Condrey, G, Chen, James J, Chirtel, Stuart, Filice, Ross W, Francis, Henry, Jiang, Hongying, Levine, Jonathan, Martin, David, Oladipo, Taiye, O’Neill, Rene, Palmer, Lee Anne M., Paredes, Antonio, Rochester, George, Sholtes, Deborah, Szarfman, Ana, Wong, Hui-Lee, Xu, Zhiheng, Kass-Hout, Taha

“…Objectives This article summarizes past and current data mining activities at the United States Food and Drug Administration (FDA). Target audience We address…”
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Assessment of performance of survival prediction models for cancer prognosis by Chen, Hung-Chia, Kodell, Ralph L, Cheng, Kuang Fu, Chen, James J

“…Cancer survival studies are commonly analyzed using survival-time prediction models for cancer prognosis. A number of different performance metrics are used to…”
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Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data by Chen, James J, Hsueh, Huey-Miin, Delongchamp, Robert R, Lin, Chien-Ju, Tsai, Chen-An

“…Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control…”
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Power and sample size estimation in microarray studies by Lin, Wei-Jiun, Hsueh, Huey-Miin, Chen, James J

“…Before conducting a microarray experiment, one important issue that needs to be determined is the number of arrays required in order to have adequate power to…”
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Identification of bicluster regions in a binary matrix and its applications by Chen, Hung-Chia, Zou, Wen, Tien, Yin-Jing, Chen, James J

“…Biclustering has emerged as an important approach to the analysis of large-scale datasets. A biclustering technique identifies a subset of rows that exhibit…”
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Evaluation of Pulsed-Field Gel Electrophoresis Profiles for Identification of Salmonella Serotypes by Zou, Wen, Lin, Wei-Jiun, Foley, Steven L, Chen, Chun-Houh, Nayak, Rajesh, Chen, James J

“…Pulsed-field gel electrophoresis (PFGE) is a standard typing method for isolates from Salmonella outbreaks and epidemiological investigations. Eight hundred…”
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A composite model for subgroup identification and prediction via bicluster analysis by Chen, Hung-Chia, Zou, Wen, Lu, Tzu-Pin, Chen, James J

“…A major challenges in the analysis of large and complex biomedical data is to develop an approach for 1) identifying distinct subgroups in the sampled…”
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Prediction System for Rapid Identification of Salmonella Serotypes Based on Pulsed-Field Gel Electrophoresis Fingerprints by WEN ZOU, LIN, Wei-Jiun, HISE, Kelley B, CHEN, Hung-Chia, KEYS, Christine, CHEN, James J

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reordering hierarchical tree based on bilateral symmetric distance by Chae, Minho, Chen, James J

“…In microarray data analysis, hierarchical clustering (HC) is often used to group samples or genes according to their gene expression profiles to study their…”
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Meta-analysis of pulsed-field gel electrophoresis fingerprints based on a constructed Salmonella database by Zou, Wen, Chen, Hung-Chia, Hise, Kelley B, Tang, Hailin, Foley, Steven L, Meehan, Joe, Lin, Wei-Jiun, Nayak, Rajesh, Xu, Joshua, Fang, Hong, Chen, James J

“…A database was constructed consisting of 45,923 Salmonella pulsed-field gel electrophoresis (PFGE) patterns. The patterns, randomly selected from all…”
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Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential by Shi, Leming, Tong, Weida, Fang, Hong, Scherf, Uwe, Han, Jing, Puri, Raj K, Frueh, Felix W, Goodsaid, Federico M, Guo, Lei, Su, Zhenqiang, Han, Tao, Fuscoe, James C, Xu, Z Alex, Patterson, Tucker A, Hong, Huixiao, Xie, Qian, Perkins, Roger G, Chen, James J, Casciano, Daniel A

“…The acceptance of microarray technology in regulatory decision-making is being challenged by the existence of various platforms and data analysis methods. A…”
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Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples by Hong, Huixiao, Su, Zhenqiang, Ge, Weigong, Shi, Leming, Perkins, Roger, Fang, Hong, Xu, Joshua, Chen, James J, Han, Tao, Kaput, Jim, Fuscoe, James C, Tong, Weida

“…Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that…”
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Pubertal delay in male nonhuman primates (Macaca mulatta) treated with methylphenidate by Mattison, Donald R, Plant, Tony M, Lin, Hui-Min, Chen, Hung-Chia, Chen, James J, Twaddle, Nathan C, Doerge, Daniel, Slikker, William Jr, Patton, Ralph E, Hotchkiss, Charlotte E, Callicott, Ralph J, Schrader, Steven M, Turner, Terry W, Kesner, James S, Vitiello, Benedetto, Petibone, Dayton M, Morris, Suzanne M

“…Juvenile male rhesus monkeys treated with methylphenidate hydrochloride (MPH) to evaluate genetic and behavioral toxicity were observed after 14 mo of…”
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Using Dietary Exposure and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling in Human Risk Extrapolations for Acrylamide Toxicity by Doerge, Daniel R., Young, John F., Chen, James J., DiNovi, Michael J., Henry, Sara H.

“…The discovery of acrylamide (AA) in many common cooked starchy foods has presented significant challenges to toxicologists, food scientists, and national…”
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Class-imbalanced classifiers for high-dimensional data by Lin, Wei-Jiun, Chen, James J

“…A class-imbalanced classifier is a decision rule to predict the class membership of new samples from an available data set where the class sizes differ…”
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Estimation of False Discovery Rates in Multiple Testing: Application to Gene Microarray Data by Tsai, Chen-An, Hsueh, Huey-miin, Chen, James J.

“…Testing for significance with gene expression data from DNA microarray experiments involves simultaneous comparisons of hundreds or thousands of genes. If R…”
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Topic modeling for cluster analysis of large biological and medical datasets by Zhao, Weizhong, Zou, Wen, Chen, James J

“…The big data moniker is nowhere better deserved than to describe the ever-increasing prodigiousness and complexity of biological and medical datasets. New…”
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Tests for equivalence or non-inferiority for paired binary data by Liu, Jen-pei, Hsueh, Huey-miin, Hsieh, Eric, Chen, James J.

“…Assessment of therapeutic equivalence or non‐inferiority between two medical diagnostic procedures often involves comparisons of the response rates between…”
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