Search Results - "Chen, J."
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Microplastics in freshwater systems: A review on occurrence, environmental effects, and methods for microplastics detection
Published in Water research (Oxford) (15-06-2018)“…The continuous increase in synthetic plastic production and poor management in plastic waste have led to a tremendous increase in the dumping into our aqueous…”
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OC10.08: A novel fetal intracranial measurement contributing to the differential diagnosis of fetal microcephaly
Published in Ultrasound in obstetrics & gynecology (01-09-2024)Get full text
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cGAS in action: Expanding roles in immunity and inflammation
Published in Science (American Association for the Advancement of Science) (08-03-2019)“…DNA is highly immunogenic. It represents a key pathogen-associated molecular pattern (PAMP) during infection. Host DNA can, however, also act as a…”
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The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer
Published in The Journal of experimental medicine (07-05-2018)“…Detection of microbial DNA is an evolutionarily conserved mechanism that alerts the host immune system to mount a defense response to microbial infections…”
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DNA-induced liquid phase condensation of cGAS activates innate immune signaling
Published in Science (American Association for the Advancement of Science) (17-08-2018)“…The binding of DNA to cyclic GMP-AMP synthase (cGAS) leads to the production of the secondary messenger cyclic GMP-AMP (cGAMP), which activates innate immune…”
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EP16.05: Transvaginal ultrasound indicators to evaluate cervical ripening and predict the outcome of induction of labour
Published in Ultrasound in obstetrics & gynecology (01-09-2022)Get full text
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Benchmarking an 11-qubit quantum computer
Published in Nature communications (29-11-2019)“…The field of quantum computing has grown from concept to demonstration devices over the past 20 years. Universal quantum computing offers efficiency in…”
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Computational Methods in Heterogeneous Catalysis
Published in Chemical reviews (27-01-2021)“…The unprecedented ability of computations to probe atomic-level details of catalytic systems holds immense promise for the fundamentals-based bottom-up design…”
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A comprehensive review on biosorption of heavy metals by algal biomass: Materials, performances, chemistry, and modeling simulation tools
Published in Bioresource technology (01-05-2014)“…•Biosorption is a highly cost-effective technology for removal of heavy metals.•Effective pretreatment approaches of biomass for better metal uptake are…”
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Multiple signal pathways in obesity‐associated cancer
Published in Obesity reviews (01-12-2011)“…Obesity is increasing worldwide and reaches to a large proportion of the population in developed countries. Thus, obesity‐associated cancer has become a major…”
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Coastal climate change, soil salinity and human migration in Bangladesh
Published in Nature climate change (01-11-2018)“…Climate change is not only altering weather patterns but also accelerating sea-level rise, leading to increased inundation and saline contamination of soils…”
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Prime editing for precise and highly versatile genome manipulation
Published in Nature reviews. Genetics (01-03-2023)“…Programmable gene-editing tools have transformed the life sciences and have shown potential for the treatment of genetic disease. Among the CRISPR–Cas…”
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Functional MRI of brain physiology in aging and neurodegenerative diseases
Published in NeuroImage (Orlando, Fla.) (15-02-2019)“…Brain aging and associated neurodegeneration constitute a major societal challenge as well as one for the neuroimaging community. A full understanding of the…”
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Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
Published in Nature immunology (01-10-2016)“…In this Review, Chen and colleagues discuss recent advances in understanding of the cGAS–STING pathway, focusing on the regulatory mechanisms and roles of this…”
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Pemetrexed versus gefitinib as a second-line treatment in advanced nonsquamous nonsmall-cell lung cancer patients harboring wild-type EGFR (CTONG0806): a multicenter randomized trial
Published in Annals of oncology (01-12-2014)“…CTONG0806 assessed the efficacy of pemetrexed versus gefitinib as second-line treatment in advanced nonsquamous nonsmall-cell lung cancer (NSCLC) harboring…”
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Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids
Published in Annual review of immunology (01-01-2014)“…The innate immune system utilizes pattern-recognition receptors (PRRs) to detect the invasion of pathogens and initiate host antimicrobial responses such as…”
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Ubiquitination in signaling to and activation of IKK
Published in Immunological reviews (01-03-2012)“…A role for polyubiquitination in the activation of inhibitor of NF‐κB (IκB) kinase (IKK) through a proteasome‐independent mechanism was first reported in 1996,…”
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Adsorptive removal of arsenic from water by an iron–zirconium binary oxide adsorbent
Published in Journal of colloid and interface science (01-06-2011)“…Arsenate is removed by Fe–Zr binary oxide through formation of inner-sphere surface complexes, while As(III) is removed by formation of both inner- and…”
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Thermal Conductivity of Graphene Laminate
Published in Nano letters (10-09-2014)“…We have investigated thermal conductivity of graphene laminate films deposited on polyethylene terephthalate substrates. Two types of graphene laminate were…”
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