Search Results - "Chen, Ih‐Sheng"

Ascleposide, a natural cardenolide, induces anticancer signaling in human castration‐resistant prostatic cancer through Na+/K+‐ATPase internalization and tubulin acetylation by Leu, Wohn‐Jenn, Wang, Ching‐Ting, Hsu, Jui‐Ling, Chen, Ih‐Sheng, Chang, Hsun‐Shuo, Guh, Jih‐Hwa

“…Background Cardiac glycosides, which inhibit Na+/K+‐ATPase, display inotropic effects for the treatment of congestive heart failure and cardiac arrhythmia…”
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Avocado (Persea americana) fruit extract (2R,4R)-1,2,4-trihydroxyheptadec-16-yne inhibits dengue virus replication via upregulation of NF-κB–dependent induction of antiviral interferon responses by Wu, Yu-Hsuan, Tseng, Chin-Kai, Wu, Ho-Cheng, Wei, Chih-Ku, Lin, Chun-Kuang, Chen, Ih-Sheng, Chang, Hsun-Shuo, Lee, Jin-Ching

“…Dengue virus (DENV) caused millions of infections around the world annually. Co-infection with different serotypes of DENV is associated with dengue…”
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Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect by Leu, Wohn-Jenn, Chang, Hsun-Shuo, Chen, Ih-Sheng, Guh, Jih-Hwa, Chan, She-Hung

“…Acute myeloid leukemia (AML) is one of the most common forms of leukemia. Despite advances in the management of such malignancies and the progress of novel…”
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Engelheptanoxides behave as liver X receptor α agonists by Liang, Yu-Hsuan, Luo, Yu-Han, Chen, Ih-Sheng, Lin, Hsiang-Ru

“…Engelheptanoxide A and C are the active ingredients isolated from Engelhardia roxburghiana , a novel traditional herbal medicine exerting pharmacological…”
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Chemical Constituents with GNMT-Promoter-Enhancing and NRF2-Reduction Activities from Taiwan Agarwood Excoecaria formosana by Wu, Ho-Cheng, Cheng, Ming-Jen, Yen, Chia-Hung, Chen, Yi-Ming Arthur, Chen, Yi-Siao, Chen, Ih-Sheng, Chang, Hsun-Shuo

“…Hepatocellular carcinoma (HCC) is considered to be a silent killer, and was the fourth leading global cause of cancer deaths in 2018. For now, sorafenib is the…”
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Chemical constituents and bioactivity of Formosan lauraceous plants by Chang, Hsun-Shuo, Chen, Ih-Sheng

“…Taiwan is rich in lauraceous plants. A review of 197 references based on the chemical analysis and bioactivity of indigenous lauraceous plants carried out by…”
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2’,3-dihydroxy-5-methoxybiphenyl suppresses fMLP-induced superoxide anion production and cathepsin G release by targeting the β-subunit of G-protein in human neutrophils by Liao, Hsiang-Ruei, Chen, Ih-Sheng, Liu, Fu-Chao, Lin, Shinn-Zhi, Tseng, Ching-Ping

“…This study investigates the effect and the underlying mechanism of 2’,3-dihydroxy-5-methoxybiphenyl (RIR-2), a lignan extracted from the roots of Rhaphiolepis…”
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Anti-Inflammatory and Antibacterial Activity Constituents from the Stem of Cinnamomum validinerve by Yang, Chi-Lung, Wu, Ho-Cheng, Hwang, Tsong-Long, Lin, Chu-Hung, Cheng, Yin-Hua, Wang, Chia-Chi, Kan, Hung-Lin, Kuo, Yueh-Hsiung, Chen, Ih-Sheng, Chang, Hsun-Shuo, Lin, Ying-Chi

“…One new dibenzocycloheptene, validinol ( ), and one butanolide firstly isolated from the natural source, validinolide ( ), together with 17 known compounds…”
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Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima by Lin, Chu-Hung, Chou, Hsiao-Jung, Chang, Chih-Chi, Chen, Ih-Sheng, Chang, Hsun-Shuo, Cheng, Tian-Lu, Kuo, Yueh-Hsiung, Ko, Horng-Huey

“…(Lauraceae) is an endemic plant in Taiwan. One new carboline alkaloid, demethoxydaibucarboline A ( ), two new eudesmanolide-type sesquiterpenes,…”
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Cinnamtannin B1 attenuates rosacea-like signs via inhibition of pro-inflammatory cytokine production and down-regulation of the MAPK pathway by Kan, Hung-Lin, Wang, Chia-Chi, Cheng, Yin-Hua, Yang, Chi-Lung, Chang, Hsun-Shuo, Chen, Ih-Sheng, Lin, Ying-Chi

“…Rosacea is a common inflammatory disease of facial skin. Dysregulation of innate immunity with enhanced inflammation and increased abundance of LL-37 at the…”
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Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle by Leu, Wohn-Jenn, Chang, Hsun-Shuo, Chan, She-Hung, Hsu, Jui-Ling, Yu, Chia-Chun, Hsu, Lih-Ching, Chen, Ih-Sheng, Guh, Jih-Hwa

“…In the past decade, there has been a profound increase in the number of studies revealing that cardenolide glycosides display inhibitory activity on the growth…”
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Aporphine alkaloids and cytotoxic lignans from the roots of Illigera luzonensis by Chen, Jih-Jung, Hung, Hsin-Chih, Sung, Ping-Jyun, Chen, Ih-Sheng, Kuo, Wen-Lung

“…Six aporphine alkaloids, (+)-( S)- N-butyrylcaaverine ( 1), (+)-( S)- N-propionylcaaverine ( 2), (+)-( S)- N-acetylcaaverine ( 3), (+)-(6a R,7 R)-…”
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Secondary Metabolites from the Endophytic Fungus Xylaria cubensis by Fan, Nai-Wen, Chang, Hsun-Shuo, Cheng, Ming-Jen, Hsieh, Sung-Yuan, Liu, Ta-Wei, Yuan, Gwo-Fang, Chen, Ih-Sheng

“…Seven new metabolites, including three sesquiterpenoids, 10‐hydroxythujopsene (1), akotriol (2), and xylaritriol (3), one diterpenoid, cubentriol (4), one…”
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Inhibitory Effects of Constituents of an Endophytic Fungus Hypoxylon investiens on Nitric Oxide and Interleukin-6 Production in RAW264.7 Macrophages by Chang, Chun-Wei, Chang, Hsun-Shuo, Cheng, Ming-Jen, Liu, Ta-Wei, Hsieh, Sung-Yuan, Yuan, Gwo-Fang, Chen, Ih-Sheng

“…Three new compounds, hypoxyloamide (1), 8‐methoxynaphthalene‐1,7‐diol (2), and hypoxylonol (3), together with seven compounds isolated from nature for the…”
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TIPdb: A Database of Anticancer, Antiplatelet, and Antituberculosis Phytochemicals from Indigenous Plants in Taiwan by Tung, C.-W., Li, Jih-Heng, Jheng, Jhao-Liang, Chen, Ih-Sheng, Wang, Chia-Chi, Lin, Ying-Chi

“…The unique geographic features of Taiwan are attributed to the rich indigenous and endemic plant species in Taiwan. These plants serve as resourceful bank for…”
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Secondary Metabolites and Antimycobacterial Activities from the Roots of Ficus nervosa by Chen, Li-Wen, Cheng, Ming-Jen, Peng, Chien-Fang, Chen, Ih-Sheng

“…Bioassay‐guided fractionation of the active AcOEt‐soluble layer led to the isolation of two new pyranocoumarins, 3‐hydroxyxanthyletin (1) and…”
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Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation by Yu, Chia-Chun, Wu, Ping-Jung, Hsu, Jui-Ling, Ho, Yunn-Fang, Hsu, Lih-Ching, Chang, Yu-Jia, Chang, Hsun-Shuo, Chen, Ih-Sheng, Guh, Jih-Hwa

“…BACKGROUND Increasing evidence suggests that mitochondria play a central role in regulating cell apoptosis. Survivin, an inhibitor of apoptosis protein (IAP)…”
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A Novel Dimeric Coumarin Analog and Antimycobacterial Constituents from Fatoua pilosa by Chiang, Chun-Ching, Cheng, Ming-Jen, Peng, Chien-Fang, Huang, Hung-Yi, Chen, Ih-Sheng

“…One novel dimeric coumarin analog, fatouapilosin (1), together with 18 known compounds, have been isolated from the whole plants of Fatoua pilosa. The…”
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Bioactive composition of Reevesia formosana root and stem with cytotoxic activity potential by Chang, Hsun-Shuo, Lin, Chu-Hung, Hsiao, Pei-Yu, Peng, Hung-Ti, Lee, Shiow-Ju, Cheng, Ming-Jen, Chen, Ih-Sheng

“…Six new compounds including three lignanoids: reevesiacoumarin ( 1 ), reevesic acid ( 2 ), and reevesilignan ( 3 ), and three terpenoids: reevesiterpenol A ( 4…”
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Cytotoxic Flavonoids from the Leaves of Cryptocarya chinensis by Chou, Tsung-Hsien, Chen, Jih-Jung, Lee, Shiow-Ju, Chiang, Michael Y, Yang, Cheng-Wei, Chen, Ih-Sheng

“…Bioassay-guided fractionation led to the isolation of six new tetrahydroflavanones, cryptochinones A−F (1−6), from the neutral CHCl3 fraction of Cryptocarya…”
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