Search Results - "Chen, Huisheng"
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Association of Headache Disorders and the Risk of Dementia: Meta-Analysis of Cohort Studies
Published in Frontiers in aging neuroscience (11-02-2022)“…The purpose of this meta-analysis is to assess whether there is an association between headache disorders and all-cause dementia, Alzheimer's disease (AD), and…”
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Safety and efficacy of tenecteplase versus alteplase in patients with acute ischaemic stroke (TRACE): a multicentre, randomised, open label, blinded-endpoint (PROBE) controlled phase II study
Published in Stroke and vascular neurology (01-02-2022)“…BackgroundTenecteplase (TNK) possesses several pharmacological characteristics superior to conventional alteplase (rt-PA), with well-established safety and…”
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3
Vav1 promotes inflammation and neuronal apoptosis in cerebral ischemia/reperfusion injury by upregulating microglial and NLRP3 inflammasome activation
Published in Neural regeneration research (01-11-2023)“…Microglia, which are the resident macrophages of the central nervous system, are an important part of the inflammatory response that occurs after cerebral…”
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Safety and efficacy of Edaravone Dexborneol versus edaravone for patients with acute ischaemic stroke: a phase II, multicentre, randomised, double-blind, multiple-dose, active-controlled clinical trial
Published in Stroke and vascular neurology (01-09-2019)“…BackgroundEdaravone Dexborneol is a novel neuroprotective agent that comprised edaravone and (+)-borneol, a food additive with an anti-inflammatory effect in…”
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Rimegepant orally disintegrating tablet 75 mg for acute treatment of migraine in adults from China: a subgroup analysis of a double-blind, randomized, placebo-controlled, phase 3 clinical trial
Published in Journal of headache and pain (16-04-2024)“…Background Rimegepant orally disintegrating tablet (ODT), an oral small-molecule calcitonin gene-related peptide receptor antagonist, is indicated for acute…”
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Image Patch-Based Net Water Uptake and Radiomics Models Predict Malignant Cerebral Edema After Ischemic Stroke
Published in Frontiers in neurology (23-12-2020)“…Malignant cerebral edema (MCE) after an ischemic stroke results in a poor outcome or death. Early prediction of MCE helps to identify subjects that could…”
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Geographic differences in pharmacotherapy patterns and outcomes of acute ischemic stroke in China
Published in BMC neurology (15-02-2024)“…Vast economic and healthcare status discrepancies exist among regions in China, contributing to different treatment patterns. This study was aimed to…”
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Effect of weekend versus weekday admission on the mortality of acute ischemic stroke patients in China: an analysis of data from the Chinese acute ischemic stroke treatment outcome registry
Published in Frontiers in neurology (17-07-2023)“…Due to disparities in medical resources in rural and urban areas as well as in different geographic regions in China, the effect of weekend versus weekday…”
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Effectiveness of intravenous r-tPA versus UK for acute ischaemic stroke: a nationwide prospective Chinese registry study
Published in Stroke and vascular neurology (01-12-2021)“…BackgroundIntravenous recombinant tissue plasminogen activator (r-tPA) and urokinase (UK) are both recommended for the treatment of acute ischaemic stroke…”
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10
Melodinhenine B attenuates NLRP3 expression in a cerebral ischemia/reperfusion-induced neuronal injury rat model
Published in Folia neuropathologica (01-01-2020)“…This investigation evaluated the neuroprotective effect of melodinhenine B in a cerebral ischemia/reperfusion (I/R)-induced neuronal injury rat model. The…”
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Predictors and Prognosis of Symptomatic Intracranial Hemorrhage in Acute Ischemic Stroke Patients Without Thrombolysis: Analysis of Data From the Chinese Acute Ischemic Stroke Treatment Outcome Registry
Published in Frontiers in neurology (28-09-2021)“…Background and Purpose: There is limited information on symptomatic intracranial hemorrhage (sICH) in stroke patients without thrombolysis. This study aimed to…”
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Efficacy and safety of cinepazide maleate injection in patients with acute ischemic stroke: a multicenter, randomized, double-blind, placebo-controlled trial
Published in BMC neurology (14-07-2020)“…Background Ischemic stroke is a leading cause of morbidity and mortality. Thrombolytic therapy improves disability and survival rates; however, to be…”
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13
A Prospective, Multicenter, Single-Group Target-Value Clinical Trial to Evaluate the Safety and Efficacy of a Large Bore Aspiration Catheter System for the Endovascular Treatment of Acute Ischemic Stroke
Published in Frontiers in neurology (09-06-2022)“…ObjectiveThis study was conducted to determine the safety and efficacy of the Esperance® Distal Access Catheter (0.071"), a novel large bore aspiration…”
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14
Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: the first multicentre, phase III trial in China
Published in Stroke and vascular neurology (01-09-2020)“…Background and purposeData on the efficacy and safety of alteplase for acute ischaemic stroke (AIS) administered 3–4.5 hours after the onset of stroke symptoms…”
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Regional Differences in Hospital Costs of Acute Ischemic Stroke in China: Analysis of Data From the Chinese Acute Ischemic Stroke Treatment Outcome Registry
Published in Frontiers in public health (10-12-2021)“…Studies on the regional differences in hospital costs of acute ischemic stroke (AIS) are scarce in China. We aimed to explore the regional differences in…”
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Characterization of nociceptive responses to bee venom-induced inflammation in neonatal rats
Published in Brain research (07-09-2012)“…Abstract To assess developmental characteristics of nociceptive responses induced by bee venom (BV) injection in neonatal rats, we exposed pups to…”
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Proposed antithrombotic strategy for acute ischemic stroke with large-artery atherosclerosis: focus on patients with high-risk transient ischemic attack and mild-to-moderate stroke
Published in Annals of translational medicine (01-01-2020)“…An effective antithrombotic strategy is required to prevent the recurrence and aggravation of large-artery atherosclerosis (LAA) stroke, especially in…”
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The neuroprotection of Sinomenine against ischemic stroke in mice by suppressing NLRP3 inflammasome via AMPK signaling
Published in International immunopharmacology (01-11-2016)“…Neuroinflammation remains the primary cause of morbidity and mortality in stroke-induced secondary brain injury. The NOD-like receptor pyrin 3 (NLRP3)…”
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Randomized trial of argatroban plus recombinant tissue-type plasminogen activator for acute ischemic stroke (ARAIS): Rationale and design
Published in The American heart journal (01-07-2020)“…Previous studies have implied the efficacy and safety of argatroban plus recombinant tissue-type plasminogen activator (r-tPA) in patients with acute ischemic…”
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20
The high incidence of insular infraction and insular thrombus in cardioembolic stroke
Published in Journal of the neurological sciences (01-12-2023)Get full text
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