Search Results - "Chen, Hsuan An"
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NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
Published in Science (American Association for the Advancement of Science) (21-12-2018)“…Molecularly targeted therapies aim to obstruct cell autonomous programs required for tumor growth. We show that mitogen-activated protein kinase (MAPK) and…”
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Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
Published in Science (American Association for the Advancement of Science) (12-05-2023)“…The response to tumor-initiating inflammatory and genetic insults can vary among morphologically indistinguishable cells, suggesting as yet uncharacterized…”
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Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination
Published in Molecular cell (07-01-2016)“…Autophagy, a cellular self-eating mechanism, is important for maintaining cell survival and tissue homeostasis in various stressed conditions. Although the…”
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Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers
Published in Nature communications (20-08-2021)“…Previous studies have suggested that PTEN loss is associated with p110β signaling dependency, leading to the clinical development of p110β-selective…”
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Older man with acute dyspnoea
Published in Emergency medicine journal : EMJ (21-03-2024)Get more information
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Establishment of 2D Crystal Heterostructures by Sulfurization of Sequential Transition Metal Depositions: Preparation, Characterization, and Selective Growth
Published in Nano letters (09-11-2016)“…A nine-layer WS2/MoS2 heterostructure is established on a sapphire substrate after sequential growth of large-area and uniform five- and four-layer MoS2 and…”
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Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers
Published in Nature communications (25-09-2019)“…Chromatin accessibility data can elucidate the developmental origin of cancer cells and reveal the enhancer landscape of key oncogenic transcriptional…”
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Influence of advanced life support response time on out-of-hospital cardiac arrest patient outcomes in Taipei
Published in PloS one (14-04-2022)“…The association between out-of-hospital cardiac arrest patient survival and advanced life support response time remained controversial. We aimed to test the…”
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Attenuation of the increase in intraocular pressure with dexmedetomidine: Systematic review with meta-analysis and trial sequential analysis
Published in Journal of clinical anesthesia (01-02-2021)“…Whether dexmedetomidine effectively attenuates the increase in intraocular pressure (IOP) remains inconclusive. We aim to evaluate the effects of…”
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Effect of resuscitative endovascular balloon occlusion of the aorta in nontraumatic out-of-hospital cardiac arrest: a multinational, multicenter, randomized, controlled trial
Published in Current controlled trials in cardiovascular medicine (13-02-2024)“…Out-of-hospital cardiac arrest (OHCA) is a significant public health issue worldwide and is associated with low survival rates and poor neurological outcomes…”
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Type-II Superlattice Infrared Photodetectors With Graphene Transparent Electrodes
Published in IEEE photonics technology letters (01-10-2017)“…In this letter, we have demonstrated that graphene can act as a transparent electrode on the p-type GaSb substrate. Wavelength-insensitive and over 95% high…”
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Influence of the Door-to-ECG Time on the Prognosis of Patients with Acute Coronary Syndrome
Published in Acta Cardiologica Sinica (01-01-2023)“…Background: The rapid acquisition of an electrocardiogram (ECG) plays a crucial role in the diagnosis and management decisions in patients with acute coronary…”
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Type-I to Type-II Transformation of Hybrid Quantum Nanostructures
Published in IEEE journal of selected topics in quantum electronics (01-09-2017)“…Hybrid nanostructures of type-I InAs quantum dots (QDs) and type-II GaSb quantum rings (QRs) separated by a GaAs spacer layer is experimentally demonstrated in…”
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Long-Wavelength In-Plane Gate InAs Quantum-Dot Phototransistors
Published in IEEE photonics technology letters (01-02-2015)“…In-plane gate transistors with and without an InAs quantum-dot (QD) absorption layer are investigated. The n-GaAs channel acts as both an absorption layer for…”
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A gene–environment-induced epigenetic program initiates tumorigenesis
Published in Nature (London) (25-02-2021)“…Tissue damage increases the risk of cancer through poorly understood mechanisms 1 . In mouse models of pancreatic cancer, pancreatitis associated with tissue…”
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Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer
Published in Cancer cell (10-08-2020)“…Despite the development of second-generation antiandrogens, acquired resistance to hormone therapy remains a major challenge in treating advanced prostate…”
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Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
Published in Cancer discovery (06-02-2023)“…Cellular senescence involves a stable cell-cycle arrest coupled to a secretory program that, in some instances, stimulates the immune clearance of senescent…”
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Rapid particle concentration for immunofluorescence enhancement by a surface acoustic wave microchip
Published in Sensors and actuators. B, Chemical (01-11-2023)“…At the initial stages of pathogenesis, biomarkers are generated in an insignificant concentration. Hence, the rapid screening for these low-abundance…”
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Paediatric oral electrical burn
Published in Emergency medicine journal : EMJ (01-07-2024)Get more information
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Speckle reduction using deformable mirrors with diffusers in a laser pico-projector
Published in Optics express (24-07-2017)“…We propose a design for speckle reduction in a laser pico-projector adopting diffusers and deformable mirrors. This research focuses on speckle noise…”
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