Search Results - "Chen, Hengwen"
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Molecular machinery and interplay of apoptosis and autophagy in coronary heart disease
Published in Journal of molecular and cellular cardiology (01-11-2019)“…Coronary heart disease (CHD) is a common heart disease and the leading cause of cardiovascular death. Apoptosis and autophagy are two forms of programmed cell…”
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Action and therapeutic targets of myosin light chain kinase, an important cardiovascular signaling mechanism
Published in Pharmacological research (01-08-2024)“…The global incidence of cardiac diseases is increasing, imposing a substantial socioeconomic burden on healthcare systems. The pathogenesis of cardiovascular…”
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Gut microbiota-derived short-chain fatty acids and hypertension: Mechanism and treatment
Published in Biomedicine & pharmacotherapy (01-10-2020)“…[Display omitted] •“SCFAs, as one of metabolites of gut microbiota, exert regulatory effects on HTN”.•“SCFAs improve HTN via activating GPCRs and inhibiting…”
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Bioactive Ingredients in Chinese Herbal Medicines That Target Non-coding RNAs: Promising New Choices for Disease Treatment
Published in Frontiers in pharmacology (21-05-2019)“…Chinese herbal medicines (CHMs) are widely used in China and have long been a powerful method to treat diseases in Chinese people. Bioactive ingredients are…”
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Epigenetic mechanisms in coronary artery disease: The current state and prospects
Published in Trends in cardiovascular medicine (01-07-2018)“…Coronary artery disease (CAD) is the leading cause of morbidity and mortality. CAD has both genetic and environmental causes. In the past two decades, the…”
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Protective effects of natural products against myocardial ischemia/reperfusion: Mitochondria-targeted therapeutics
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Patients with ischemic heart disease receiving reperfusion therapy still need to face left ventricular remodeling and heart failure after myocardial…”
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Effects of COVID-19 on the cardiovascular system: A mendelian randomization study
Published in Sports medicine and health science (01-09-2024)“…Infections with the coronavirus disease 2019 (COVID-19) and disorders of the heart and blood vessels are causally related. To ascertain the causal relationship…”
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Relevance of Ferroptosis to Cardiotoxicity Caused by Anthracyclines: Mechanisms to Target Treatments
Published in Frontiers in cardiovascular medicine (13-06-2022)“…Anthracyclines (ANTs) are a class of anticancer drugs widely used in oncology. However, the clinical application of ANTs is limited by their cardiotoxicity…”
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Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway
Published in Frontiers in pharmacology (19-11-2024)Get full text
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Impact of the COVID-19 pandemic lockdown on hospitalizations for cerebrovascular disease and related in-hospital mortality in China: A nationwide observational study
Published in Archives of gerontology and geriatrics (01-01-2023)“…•A strict COVID-19 epidemic clearance policy might impact the outcomes of hospitalized patients.•During the COVID-19 pandemic lockdown, hospitalized patients…”
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Inhibition effect of miR-150 on the progression of oral squamous cell carcinoma by data analysis model based on independent sample T-test
Published in Saudi journal of biological sciences (01-02-2020)“…To explore the influence of mir-150 (M-150) ornithine decarboxylase (ODC) or inhibition in the development of oral squamous cell carcinoma (OSCC), the…”
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Efficacy and safety of traditional Chinese medicine injections in the treatment of acute myocardial infarction: A protocol for systematic review and network meta-analysis
Published in Medicine (Baltimore) (07-08-2020)“…As one of the common cardiovascular diseases, acute myocardial infarction (AMI) is characterized by a high mortality rate, frequent complications, and a…”
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Traditional Chinese medicine on treating dilated cardiomyopathy: A protocol for systematic review and meta analysis
Published in Medicine (Baltimore) (02-07-2020)“…Dilated cardiomyopathy (DCM) is a type of complex cardiomyopathy characterized by enlargement and contractile dysfunction of the left ventricle, right…”
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New insights into the effect of molecular crowding environment induced by dimethyl sulfoxide on the conformation and stability of G-quadruplex
Published in Chinese chemical letters (01-03-2023)“…Various structures of G-quadruplex in biosystems play an important role in different diseases and are often regulated by a variety of molecular crowding…”
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Spiky metal-organic framework nanosystem for enhanced cuproptosis-mediated cancer immunotherapy
Published in Nano today (01-06-2024)“…Immunotherapy, particularly αPD-1 therapy, has been hailed as a significant breakthrough in cancer treatment. However, the limited response rates and unknown…”
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Effects of Danlou tablet for the treatment of stable angina pectoris: A study protocol of a randomized, double-blind, and placebo-controlled clinical trial
Published in Medicine (Baltimore) (04-12-2020)“…Stable angina pectoris has a high prevalence and causes serious harm. Revascularization therapy can relieve angina pectoris to some extent, but it is not…”
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New insights into the effect of molecular crowding environment induced by dimethyl sulfoxide on the conformation and stability of G-quadruplex
Published in 中国化学快报(英文版) (2023)“…Various structures of G-quadruplex in biosystems play an important role in different diseases and are often regulated by a variety of molecular crowding…”
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Paeoniflorin improves cardiac function and decreases adverse postinfarction left ventricular remodeling in a rat model of acute myocardial infarction
Published in Drug design, development and therapy (01-01-2018)“…Paeoniflorin (PF) is the active component of Pall. or Lynch. This study was, therefore, aimed to evaluate the improvement and mechanism of the PF on…”
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Mitochondrial Damage in Myocardial Ischemia/Reperfusion Injury and Application of Natural Plant Products
Published in Oxidative medicine and cellular longevity (2022)“…Ischemic heart disease (IHD) is currently one of the leading causes of death among cardiovascular diseases worldwide. In addition, blood reflow and reperfusion…”
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