Search Results - "Chen, Hanbin"
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LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway
Published in Stem cell research & therapy (21-01-2020)“…Extracellular vesicles, especially exosomes, have emerged as key mediators of intercellular communication with the potential to improve cardiac function as…”
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Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing
Published in Clinical cancer research (01-09-2017)“…To identify tumor-derived exosomal biomarkers that are able to discriminate between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in…”
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Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine
Published in Chinese medicine (06-11-2019)“…Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer activities, including anti-proliferative, pro-apoptotic, anti-metastatic,…”
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Immune checkpoint inhibitor induces cardiac injury through polarizing macrophages via modulating microRNA-34a/Kruppel-like factor 4 signaling
Published in Cell death & disease (24-07-2020)“…Cancer immunotherapy has become a well-established treatment option for some cancers; however, its use is hampered by its cardiovascular adverse effects…”
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Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission
Published in Biochemical pharmacology (01-10-2021)“…[Display omitted] Ample evidence indicates that maternal immune activation (MIA) during gestation is linked to an increased risk for neurodevelopmental and…”
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Oxyberberine, an absorbed metabolite of berberine, possess superior hypoglycemic effect via regulating the PI3K/Akt and Nrf2 signaling pathways
Published in Biomedicine & pharmacotherapy (01-05-2021)“…[Display omitted] •Berberine and oxyberberine existed mainly as protein-bound form in blood.•Berberine was transformed into an absorbed metabolite oxyberberine…”
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Reflections on treatment of COVID-19 with traditional Chinese medicine
Published in Chinese medicine (03-09-2020)“…Coronavirus disease 2019 (COVID-19) pandemic is spreading rapidly around the globe. By the establishment of an integrative system combining both traditional…”
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PD-1 inhibitor inducing exosomal miR-34a-5p expression mediates the cross talk between cardiomyocyte and macrophage in immune checkpoint inhibitor–related cardiac dysfunction
Published in Journal for immunotherapy of cancer (01-10-2020)“…BackgroundImmune checkpoint inhibitors (ICIs) have been an important therapeutic advancement in the field of cancer medicine. Recent reports provided greater…”
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Tetrahydrocurcumin ameliorates hepatic steatosis by restoring hepatocytes lipophagy through mTORC1-TFEB pathway in nonalcoholic steatohepatitis
Published in Biomedicine & pharmacotherapy (01-09-2024)“…To investigate the therapeutic effect and underlying mechanism of tetrahydrocurcumin (THC) on nonalcoholic steatohepatitis (NASH) induced by high-fat diet…”
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Epiberberine, a natural protoberberine alkaloid, inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism
Published in European journal of pharmaceutical sciences (15-12-2017)“…In our previous study, Rhizoma Coptidis extract was found to exert more potent inhibitory effect than its major component berberine towards urease from…”
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Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms
Published in Life sciences (1973) (15-01-2018)“…The aim of this study was to comparatively investigate the potential gastroprotective effect and underlying mechanisms of coptisine free base (CFB,…”
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Electrochemical evaluation of DNA methylation level based on the stoichiometric relationship between purine and pyrimidine bases
Published in Biosensors & bioelectronics (15-07-2013)“…An efficient electrochemical approach for the evaluation of DNA methylation level was proposed according to the oxidation signal of DNA bases at an…”
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Transformation of patchouli alcohol to β-patchoulene by gastric juice: β-patchoulene is more effective in preventing ethanol-induced gastric injury
Published in Scientific reports (17-07-2017)“…Pogostemonis Herba is a functional food approved in Asian countries. Its major constituent, patchouli alcohol (PA), possesses a gastroprotective effect and is…”
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In Vivo Screening of Xanthones from Garcinia oligantha Identified Oliganthin H as a Novel Natural Inhibitor of Convulsions
Published in Journal of natural products (Washington, D.C.) (24-12-2020)“…Epilepsy is a chronic neurological disorder, characterized by recurrent, spontaneous, and transient seizures, and affects more than 70 million people…”
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Correction to: LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway
Published in Stem cell research & therapy (03-09-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Coptisine-induced inhibition of Helicobacter pylori: elucidation of specific mechanisms by probing urease active site and its maturation process
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2018)“…In this study, we examined the anti-Helicobactor pylori effects of the main protoberberine-type alkaloids in Rhizoma Coptidis. Coptisine exerted varying…”
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The discovery of berberine erythrocyte-hemoglobin self-assembly delivery system: a neglected carrier underlying its pharmacokinetics
Published in Drug delivery (01-12-2022)“…Berberine (BBR) has extremely low concentration and high tissue distribution. However, current pharmacokinetic studies predominantly focus on its concentration…”
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Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly
Published in Frontiers in immunology (19-02-2019)“…Mucosal-associated invariant T (MAIT) cells, which are enriched in human blood and express a semi-invariant TCR chain, play important roles in conditions such…”
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Role of endocrine disruption in toxicity of 6-benzylaminopurine (6-BA) to early-life stages of Zebrafish
Published in Ecotoxicology and environmental safety (01-03-2022)“…6-benzylaminopurine (6-BA), classified as a “plant hormone”, is an important ingredient in production of “toxic bean sprouts”. Although there is no direct…”
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Curcumin and its analog alleviate diabetes-induced damages by regulating inflammation and oxidative stress in brain of diabetic rats
Published in Diabetology and metabolic syndrome (18-02-2021)“…Diabetic encephalopathy is a severe diabetes complication with cognitive dysfunction and neuropsychiatric disability. The mechanisms underlying diabetic…”
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