Search Results - "Chen, Hanbin"

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  1. 1

    LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway by Chen, Hanbin, Xia, Wenzheng, Hou, Meng

    Published in Stem cell research & therapy (21-01-2020)
    “…Extracellular vesicles, especially exosomes, have emerged as key mediators of intercellular communication with the potential to improve cardiac function as…”
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  2. 2

    Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing by Jin, Xiance, Chen, Yanfan, Chen, Hanbin, Fei, Shaoran, Chen, Didi, Cai, Xiaona, Liu, Linger, Lin, Baochai, Su, Huafang, Zhao, Lihao, Su, Meng, Pan, Huanle, Shen, Lanxiao, Xie, Deyao, Xie, Congying

    Published in Clinical cancer research (01-09-2017)
    “…To identify tumor-derived exosomal biomarkers that are able to discriminate between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in…”
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  3. 3

    Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine by Luo, Hua, Vong, Chi Teng, Chen, Hanbin, Gao, Yan, Lyu, Peng, Qiu, Ling, Zhao, Mingming, Liu, Qiao, Cheng, Zehua, Zou, Jian, Yao, Peifen, Gao, Caifang, Wei, Jinchao, Ung, Carolina Oi Lam, Wang, Shengpeng, Zhong, Zhangfeng, Wang, Yitao

    Published in Chinese medicine (06-11-2019)
    “…Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer activities, including anti-proliferative, pro-apoptotic, anti-metastatic,…”
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  4. 4

    Immune checkpoint inhibitor induces cardiac injury through polarizing macrophages via modulating microRNA-34a/Kruppel-like factor 4 signaling by Xia, Wenzheng, Zou, Changlin, Chen, Hanbin, Xie, Congying, Hou, Meng

    Published in Cell death & disease (24-07-2020)
    “…Cancer immunotherapy has become a well-established treatment option for some cancers; however, its use is hampered by its cardiovascular adverse effects…”
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  5. 5

    Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission by Yang, Youjun, Wang, Baojia, Zhong, Zhanqion, Chen, Hanbin, Ding, Weijun, Hoi, Maggie Pui Man

    Published in Biochemical pharmacology (01-10-2021)
    “…[Display omitted] Ample evidence indicates that maternal immune activation (MIA) during gestation is linked to an increased risk for neurodevelopmental and…”
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  6. 6

    Oxyberberine, an absorbed metabolite of berberine, possess superior hypoglycemic effect via regulating the PI3K/Akt and Nrf2 signaling pathways by Dou, Yaoxing, Huang, Ronglei, Li, Qiaoping, Liu, Yuhong, Li, Yucui, Chen, Hanbin, Ai, Gaoxiang, Xie, Jianhui, Zeng, Huifang, Chen, Jiannan, Luo, Chaodan, Su, Ziren

    Published in Biomedicine & pharmacotherapy (01-05-2021)
    “…[Display omitted] •Berberine and oxyberberine existed mainly as protein-bound form in blood.•Berberine was transformed into an absorbed metabolite oxyberberine…”
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  7. 7

    Reflections on treatment of COVID-19 with traditional Chinese medicine by Luo, Hua, Gao, Yan, Zou, Jian, Zhang, Siyuan, Chen, Hanbin, Liu, Qiao, Tan, Dechao, Han, Yan, Zhao, Yonghua, Wang, Shengpeng

    Published in Chinese medicine (03-09-2020)
    “…Coronavirus disease 2019 (COVID-19) pandemic is spreading rapidly around the globe. By the establishment of an integrative system combining both traditional…”
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  8. 8

    PD-1 inhibitor inducing exosomal miR-34a-5p expression mediates the cross talk between cardiomyocyte and macrophage in immune checkpoint inhibitor–related cardiac dysfunction by Xia, Wenzheng, Chen, Hanbin, Chen, Didi, Ye, Yijia, Xie, Congying, Hou, Meng

    Published in Journal for immunotherapy of cancer (01-10-2020)
    “…BackgroundImmune checkpoint inhibitors (ICIs) have been an important therapeutic advancement in the field of cancer medicine. Recent reports provided greater…”
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  9. 9

    Tetrahydrocurcumin ameliorates hepatic steatosis by restoring hepatocytes lipophagy through mTORC1-TFEB pathway in nonalcoholic steatohepatitis by Wu, Jiazhen, Guan, Fengkun, Huang, Haipiao, Chen, Hanbin, Liu, Yuhong, Zhang, Shangbin, Li, Muxia, Chen, Jianping

    Published in Biomedicine & pharmacotherapy (01-09-2024)
    “…To investigate the therapeutic effect and underlying mechanism of tetrahydrocurcumin (THC) on nonalcoholic steatohepatitis (NASH) induced by high-fat diet…”
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  10. 10

    Epiberberine, a natural protoberberine alkaloid, inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism by Tan, Lihua, Li, Cailan, Chen, Hanbin, Mo, Zhizhun, Zhou, Jiangtao, Liu, Yuhong, Ma, Zhilin, Xu, Yuyao, Yang, Xiaobo, Xie, Jianhui, Su, Ziren

    “…In our previous study, Rhizoma Coptidis extract was found to exert more potent inhibitory effect than its major component berberine towards urease from…”
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  11. 11

    Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms by Luo, Chaodan, Chen, Hanbin, Wang, Yongfu, Lin, Guosheng, Li, Cailan, Tan, Lihua, Su, Ziren, Lai, Xiaoping, Xie, Jianhui, Zeng, Huifang

    Published in Life sciences (1973) (15-01-2018)
    “…The aim of this study was to comparatively investigate the potential gastroprotective effect and underlying mechanisms of coptisine free base (CFB,…”
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  12. 12

    Electrochemical evaluation of DNA methylation level based on the stoichiometric relationship between purine and pyrimidine bases by Wang, Po, Chen, Hanbin, Tian, Jiuying, Dai, Zong, Zou, Xiaoyong

    Published in Biosensors & bioelectronics (15-07-2013)
    “…An efficient electrochemical approach for the evaluation of DNA methylation level was proposed according to the oxidation signal of DNA bases at an…”
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  13. 13

    Transformation of patchouli alcohol to β-patchoulene by gastric juice: β-patchoulene is more effective in preventing ethanol-induced gastric injury by Liu, Yuhong, Liang, Jiali, Wu, Jiazhen, Chen, Hanbin, Zhang, Zhenbiao, Yang, Hongmei, Chen, Liping, Chen, Haiming, Su, Ziren, Li, Yucui

    Published in Scientific reports (17-07-2017)
    “…Pogostemonis Herba is a functional food approved in Asian countries. Its major constituent, patchouli alcohol (PA), possesses a gastroprotective effect and is…”
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  14. 14

    In Vivo Screening of Xanthones from Garcinia oligantha Identified Oliganthin H as a Novel Natural Inhibitor of Convulsions by Gong, Guiyi, Chen, Hanbin, Kam, Hiotong, Chan, Ging, Tang, Yue-xun, Wu, Man, Tan, Hongsheng, Tse, Yu-chung, Xu, Hong-xi, Lee, Simon Ming-yuen

    “…Epilepsy is a chronic neurological disorder, characterized by recurrent, spontaneous, and transient seizures, and affects more than 70 million people…”
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  15. 15
  16. 16

    Coptisine-induced inhibition of Helicobacter pylori: elucidation of specific mechanisms by probing urease active site and its maturation process by Li, Cailan, Huang, Ping, Wong, Kambo, Xu, Yifei, Tan, Lihua, Chen, Hanbin, Lu, Qiang, Luo, Chaodan, Tam, Chunlai, Zhu, Lixiang, Su, Ziren, Xie, Jianhui

    “…In this study, we examined the anti-Helicobactor pylori effects of the main protoberberine-type alkaloids in Rhizoma Coptidis. Coptisine exerted varying…”
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  17. 17

    The discovery of berberine erythrocyte-hemoglobin self-assembly delivery system: a neglected carrier underlying its pharmacokinetics by Yu, Qiuxia, Li, Minhua, Chen, Hanbin, Xu, Lieqiang, Cheng, Juanjuan, Lin, Guoshu, Liu, Yuhong, Su, Ziren, Yang, Xiaobo, Li, Yucui, Chen, Jiannan, Xie, Jianhui

    Published in Drug delivery (01-12-2022)
    “…Berberine (BBR) has extremely low concentration and high tissue distribution. However, current pharmacokinetic studies predominantly focus on its concentration…”
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  18. 18

    Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly by Chen, Pengcheng, Deng, Wenhai, Li, Dandan, Zeng, Tai, Huang, Ling, Wang, Qun, Wang, Jinli, Zhang, Weiguang, Yu, Xiaoxiao, Duan, Deming, Wang, Jinle, Xia, Hong, Chen, Hanbin, Huang, Wesley, Li, Jingao, Zhang, Dahong, Zhong, Xiao-Ping, Gao, Jimin

    Published in Frontiers in immunology (19-02-2019)
    “…Mucosal-associated invariant T (MAIT) cells, which are enriched in human blood and express a semi-invariant TCR chain, play important roles in conditions such…”
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  19. 19

    Role of endocrine disruption in toxicity of 6-benzylaminopurine (6-BA) to early-life stages of Zebrafish by Gong, Guiyi, Kam, Hiotong, Chen, Hanbin, Chen, Yan, Cheang, Wai san, Giesy, John P., Zhou, Qiaohong, Lee, Simon Ming-yuen

    Published in Ecotoxicology and environmental safety (01-03-2022)
    “…6-benzylaminopurine (6-BA), classified as a “plant hormone”, is an important ingredient in production of “toxic bean sprouts”. Although there is no direct…”
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  20. 20

    Curcumin and its analog alleviate diabetes-induced damages by regulating inflammation and oxidative stress in brain of diabetic rats by Miao, Chengfeng, Chen, Hanbin, Li, Yulian, Guo, Ying, Xu, Feifei, Chen, Qi, Zhang, Yanyan, Hu, Mengjun, Chen, Guorong

    Published in Diabetology and metabolic syndrome (18-02-2021)
    “…Diabetic encephalopathy is a severe diabetes complication with cognitive dysfunction and neuropsychiatric disability. The mechanisms underlying diabetic…”
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