Search Results - "Chen, Fentian"
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A glycoengineered therapeutic anti-HBV antibody that allows increased HBsAg immunoclearance improves HBV suppression in vivo
Published in Frontiers in pharmacology (27-12-2023)“…The effective and persistent suppression of hepatitis B surface antigen (HBsAg) in patients with chronic HBV infection (CHB) is considered to be a promising…”
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Efficient development of a stable cell pool for antibody production using a single plasmid
Published in Journal of biochemistry (Tokyo) (01-05-2018)Get full text
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Risedronate-functionalized manganese-hydroxyapatite amorphous particles: A potent adjuvant for subunit vaccines and cancer immunotherapy
Published in Journal of controlled release (01-03-2024)“…The cGAS-STING pathway and the Mevalonate Pathway are druggable targets for vaccine adjuvant discovery. Manganese (Mn) and bisphosphonates are known to exert…”
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Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR
Published in Applied microbiology and biotechnology (01-07-2018)“…Antibody drugs have been used to treat a number of diseases successfully. Producing antibodies with high yield and quality is necessary for clinical…”
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Novel electrochemical biosensor based on functional composite nanofibers for sensitive detection of p53 tumor suppressor gene
Published in Analytica chimica acta (26-02-2013)“…[Display omitted] ► A novel electrochemical p53 biosensor based on functional composite nanofibers (MWNTs–PA6–PPy) was developed. ► The MWNTs–PA6–PPy electrode…”
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Efficient development of a stable cell pool for antibody production using a single plasmid
Published in Journal of biochemistry (Tokyo) (01-05-2018)“…Therapeutic antibodies are the fastest growing group of biopharmaceuticals. Evaluation of drug candidates requires a sufficient amount of antibodies…”
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Engineering heavy chain antibody-drug conjugates against solid tumors for a one-shot kill
Published in Cancer communications (London, England) (25-10-2024)Get full text
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HBsAg and TLR7/8 dual-targeting antibody-drug conjugates induce sustained anti-HBV activity in AAV/HBV mice: a preliminary study
Published in Antibody therapeutics (01-07-2024)“…Hepatitis B virus (HBV) infection is a significant global health concern due to elevated immunosuppressive viral antigen levels, the host immune system's…”
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Development of functional antibodies against influenza B virus by activation-induced cytidine deaminase in hybridoma cells
Published in Virologica Sinica (01-08-2022)“…•Class-switch recombination was mimicked in hybridomas by controllable expression of activation-induced cytidine deaminase.•IgG antibodies were generated…”
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Novel electrochemical biosensor based on functional composite nanofibers for sensitive detection of p53 tumor suppressor gene
Published in Analytica chimica acta (01-02-2013)Get full text
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