Search Results - "Chen, Fang‐An"

CTLA-4 blockade augments human T lymphocyte-mediated suppression of lung tumor xenografts in SCID mice by SABEL, Michael S, HESS, Stephen D, EGILMEZ, Nejat K, CONWAY, Thomas F, CHEN, Fang-An, BANKERT, Richard B

“…Previous studies by others using transplantable murine tumor models have demonstrated that the administration of antibodies that block CTLA-4 interaction with…”
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Biodegradable polymer-mediated intratumoral delivery of cisplatin for treatment of human head and neck squamous cell carcinoma in a chimeric mouse model by Chen, Fang-An, Kuriakose, M. Abraham, Zhou, Ming-Xing, DeLacure, Mark D., Dunn, Richard L.

“…Background. The effectiveness of chemotherapeutic agents is proportional to the dose of the agents at their targets; however, the dose is limited by systemic…”
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CD40‐CD40 ligand (CD154) engagement is required but not sufficient for modulating MHC class I, ICAM‐1 and Fas expression and proliferation of human non‐small cell lung tumors by Yamada, Makoto, Shiroko, Takashi, Kawaguchi, Yoshihiro, Sugiyama, Yasuyuki, Egilmez, Nejat K., Chen, Fang‐An, Bankert, Richard B.

“…To determine the possible functional significance of CD40 expression on human non‐small cell lung carcinomas and to assess the potential of CD40 as a…”
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Adhesion Molecules as Prognostic Factors in Nasopharyngeal Carcinoma by Shnayder, Yelizaveta, Kuriakose, M. Abraham, Yee, Herman, Chen, Fang-An, DeLacure, Mark D., Xue, Xiao Nan, Jagirdar, Jaishree

“…Objective/Hypothesis To identify the significance of molecular markers in determining the risk of recurrence and distant metastases in nasopharyngeal…”
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Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice by SUGANO, Masahiko, EGILMEZ, Nejat K, YOKOTA, Sandra J, CHEN, Fang-An, HARDING, Jennifer, SHI KUN HUANG, BANKERT, Richard B

“…Beta1 integrins, expressed on the cell surface of human non-small cell lung carcinomas, are used here as a target for the selective delivery of anti-cancer…”
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Human CD4+ effector T cells mediate indirect interleukin-12- and interferon-γ-dependent suppression of autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice by EGILMEZ, Nejat K, HESS, Stephen D, CHEN, Fang-An, TAKITA, Hiroshi, CONWAY, Thomas F, BANKERT, Richard B

“…A human/severe combined immunodeficient mouse chimeric model was used to demonstrate that peripheral blood leukocytes (PBLs) from a patient with lung cancer…”
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CD40 expression on human lung cancer correlates with metastatic spread by SABEL, M. S, YAMADA, M, KAWAGUCHI, Y, CHEN, F.-A, TAKITA, H, BANKERT, R. B

“…The poor prognosis associated with lung cancer is related to the high incidence of regional and distant metastasis. There is a crucial need to identify…”
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Antitumor immune response of human peripheral blood lymphocytes coengrafted with tumor into severe combined immunodeficient mice by IWANUMA, Y, CHEN, F.-A, EGILMEZ, N. K, TAKITA, H, BANKERT, R. B

“…Here, it is established that human peripheral blood lymphocytes (HuPBLs), injected s.c. with a human lung tumor into severe combined immunodeficient (SCID)…”
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Doxorubicin encapsulated in sterically stabilized liposomes is superior to free drug or drug-containing conventional liposomes at suppressing growth and metastases of human lung tumor xenografts by SAKAKIBARA, T, CHEN, F.-A, KIDA, H, KUNIEDA, K, CUENCA, R. E, MARTIN, F. J, BANKERT, R. B

“…Liposomes containing polyethylene glycol-derivatized phospholipids are able to evade the reticuloendothelial system and thereby remain in circulation for…”
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Cytokine immunotherapy of cancer with controlled release biodegradable microspheres in a human tumor xenograft/SCID mouse model by EGILMEZ, N. K, JONG, Y. S, IWANUMA, Y, JACOB, J. S, SANTOS, C. A, CHEN, F.-A, MATHIOWITZ, E, BANKERT, R. B

“…A novel biodegradable poly(lactic acid) microsphere formulation was evaluated for in vivo cytokine immunotherapy of cancer in a human tumor xenograft/ severe…”
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Growth of human tumor xenografts in SCID mice quantified using an immunoassay for tumor marker protein in serum by Conway, Thomas F, Sabel, Michael S, Sugano, Masahiko, Frelinger, John G, Egilmez, Nejat K, Chen, Fang-An, Bankert, Richard B

“…The accurate measurement of the response of a tumor to a given treatment is critical to evaluating novel therapeutic modalities. An experimental design is…”
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Monoclonal antibodies directed against the T-cell activation molecule CD137 (interleukin-A or 4-1BB) block human lymphocyte-mediated suppression of tumor xenografts in severe combined immunodeficient mice by SABEL, M. S, CONWAY, T. F, CHEN, F.-A, BANKERT, R. B

“…A monoclonal antibody specific for the human analog of the murine T-cell activation molecule 4-1BB was generated and is shown here to react selectively with…”
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Engraftment of human tumor-infiltrating lymphocytes and the production of anti-tumor antibodies in SCID mice by Williams, SS, Chen, FA, Kida, H, Yokata, S, Miya, K, Kato, M, Barcos, MP, Wang, HQ, Alosco, T, Umemoto, T, Croy, BA, Repasky, EA, Bankert, RB

“…We report here the placement of nondisrupted 1-mm3 pieces of fresh human lung tumor biopsy tissue into the subcutis of severe combined immunodeficient (SCID)…”
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Human antibody response in human peripheral blood leukocyte/severe combined immunodeficient chimeric model is dependent on B and T cell costimulation via CD40/CD40 ligand by Chen, FA, Williams, SS, Fanslow, WC, Bankert, RB

“…We have used a human/severe combined immunodeficient (SCID) mouse chimeric model (in which human PBLs are engrafted into SCID mice) to investigate in vivo the…”
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Tissue-Specific Gene Expression of Head and Neck Squamous Cell Carcinoma In Vivo by Complementary DNA Microarray Analysis by Sok, John C, Kuriakose, M. Abraham, Mahajan, Vinit B, Pearlman, Aaron N, DeLacure, Mark D, Chen, Fang-An

“…OBJECTIVES To identify distinct gene expression profiles of human head and neck squamous cell carcinomas (HNSCCAs) using complementary DNA (cDNA) microarray…”
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Combination methods in microarray analysis by Han-Yu Chuang, Hongfang Liu, Fang-An Chen, Cheng-Yan Kao, Hsu, D.F.

“…Microarray technology and experiment can produce thousands or tens of thousands of gene expression measurements in a single cellular mRNA sample. Selecting a…”
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Cationic poly(VCL–AETA) hydrogels and ovalbumin (OVA) release in vitro by Wu, Da-Qing, Chu, Chih-Chang, Chen, Fang An

“…The objective of this research is to explore the synthesis of a new family of water soluble polycationic copolymeric precursors that could be photo-crosslinked…”
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Effects of Precursor and Cross-linking Parameters on the Properties of Dextran-Allyl Isocyanate-Ethylamine/Poly(ethylene glycol diacrylate) Biodegradable Hydrogels and Their Release of Ovalbumin by Sun, Guoming, Chen, Fang An, Chu, Chih-Chang

“…In this paper, we studied the effects of molecular weight of poly(ethylene glycol diacrylate) (PEGDA) precursor, the degree of substitution (DS) of both allyl…”
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Low-Dose Ethanol Preconditioning Protects Against Oxygen- Glucose Deprivation/Reoxygenation-Induced Neuronal Injury By Activating Large Conductance, Ca2＋-Activated K＋ Channels In Vitro by Su, Fang, Guo, An-Chen, Li, Wei-Wei, Zhao, Yi-Long, Qu, Zheng-Yi, Wang, Yong-Jun, Wang, Qun, Zhu, Yu-Lan

“…Increasing evidence suggests that low to mod- erate ethanol ingestion protects against the deleterious effects of subsequent ischemia/reperfusion; however, the…”
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Membrane-associated glycoprotein (gp160) identified on human lung tumors by a monoclonal antibody by ZYLSTRA, S, FANG-AN CHEN, GHOSH, S. K, REPASKY, E. A, RAO, U, TAKITA, H, BANKERT, R. B

“…A monoclonal antibody (5E8) has been used to identify and structurally characterize a previously unreported macromolecule present on the surface of human lung…”
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