Search Results - "Chen, Elizabeth Suchi"
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SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer’s Disease
Published in Neurochemistry international (01-12-2012)“…► We measured SORL1 and SIRT1 expression and methylation in Alzheimer’s Disease and aging. ► We evaluated these levels in post mortem brain tissues and…”
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2
Histone Modifications in Alzheimer's Disease
Published in Genes (29-01-2023)“…Since Late-onset Alzheimer's disease (LOAD) derives from a combination of genetic variants and environmental factors, epigenetic modifications have been…”
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Interrelationship between chromosome 8 aneuploidy, C-MYC amplification and increased expression in individuals from northern Brazil with gastric adenocarcinoma
Published in World journal of gastroenterology : WJG (14-10-2006)“…AIM: To investigate chromosome 8 numerical aberrations, C-MYC oncogene alterations and its expression in gastric cancer and to correlate these findings with…”
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Pharmacogenetic Analyses of Therapeutic Effects of Lipophilic Statins on Cognitive and Functional Changes in Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2022)“…Pharmacogenetic effects of statins on clinical changes in Alzheimer's disease (AD) could be mediated by epistatic interactions among relevant genetic variants…”
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The Complex Network between MYC Oncogene and microRNAs in Gastric Cancer: An Overview
Published in International journal of molecular sciences (05-03-2020)“…Despite the advancements in cancer treatments, gastric cancer is still one of the leading causes of death worldwide. In this context, it is of great interest…”
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Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2018)“…Lifetime risk factors for cognitive and functional decline in Alzheimer's disease (AD) are not fully understood, and were prospectively evaluated in patients…”
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Analyses of the pericyte transcriptome in ischemic skeletal muscles
Published in Stem cell research & therapy (16-03-2021)“…Peripheral arterial disease (PAD) affects millions of people and compromises quality of life. Critical limb ischemia (CLI), which is the most advanced stage of…”
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Differential regulation of LRRC37A2 in gastric cancer by DNA methylation
Published in Epigenetics (2022)“…Gastric cancer (GC) is one of the leading types of fatal cancer worldwide. Epigenetic manipulation of cancer cells is a useful tool to better understand gene…”
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BMP8B Is a Tumor Suppressor Gene Regulated by Histone Acetylation in Gastric Cancer
Published in Journal of cellular biochemistry (01-04-2017)“…ABSTRACT Different from genetic alterations, the reversible nature of epigenetic modifications provides an interesting opportunity for the development of…”
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10
Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines
Published in World journal of gastroenterology : WJG (21-11-2016)“…AIM To identify common copy number alterations on gastric cancer cell lines.METHODS Four gastric cancer cell lines(ACP02, ACP03, AGP01 and PG100) underwent…”
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CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients
Published in Journal of Alzheimer's disease (01-01-2013)“…Alzheimer's disease (AD) is a highly prevalent type of dementia in the elderly population. AD is a complex neurodegenerative disorder. Thus, epigenetic…”
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Pharmacogenetic effects of angiotensin-converting enzyme inhibitors over age-related urea and creatinine variations in patients with dementia due to Alzheimer disease
Published in Colombia medica (Cali, Colombia) (30-06-2016)“…Background: Renal function declines according to age and vascular risk factors, whereas few data are available regarding geneticallymediated effects of…”
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MYC, TP53, and Chromosome 17 Copy-Number Alterations in Multiple Gastric Cancer Cell Lines and in Their Parental Primary Tumors
Published in Journal of biomedicine & biotechnology (01-01-2011)“…We evaluated whether MYC, TP53, and chromosome 17 copy-number alterations occur in ACP02, ACP03, and AGP01 gastric cancer cell lines and in their tumor…”
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14
Association of PPARα gene polymorphisms and lipid serum levels in a Brazilian elderly population
Published in Experimental and molecular pathology (01-02-2010)“…Peroxisome proliferator-activated receptor α (PPARα) is a nuclear transcription factor strictly involved in lipid and lipoprotein metabolisms. Thus, PPARα gene…”
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C-MYC Locus Amplification as Metastasis Predictor in Intestinal-type Gastric Adenocarcinomas: CGH Study in Brazil
Published in Anticancer research (01-07-2006)“…Background: The genetic events involved in gastric cancer, the third most frequent cancer in the world with a high incidence in Pará State, Brazil, remain…”
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Association of lipase lipoprotein polymorphisms with myocardial infarction and lipid levels
Published in Clinical chemistry and laboratory medicine (01-01-2007)“…Lipoprotein lipase has an important role in lipid metabolism. Elevated levels of very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) are…”
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Variations in metabolic risk factors for dementia do not affect APOE‐mediated cognitive or functional decline in patients with Alzheimer’s disease from São Paulo, Brazil
Published in Alzheimer's & dementia (01-12-2023)“…Background Midlife cerebrovascular risk, low education and copies of APOE‐ε4 are risk factors for Alzheimer’s disease (AD), whereas metabolic derangements have…”
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APOE ε4 Carrier Status as Mediator of Effects of Psychotropic Drugs on Clinical Changes in Patients With Alzheimer's Disease
Published in The journal of neuropsychiatry and clinical neurosciences (01-10-2022)“…Neuropsychiatric syndromes have been associated with memory dysfunction and risk of and earlier onset of dementia, but how psychotropic drugs affect clinical…”
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Longitudinal lipid profile variations and clinical change in Alzheimer's disease dementia
Published in Neuroscience letters (12-04-2017)“…•APOE4- carriers with AD trended toward functional benefits with raising LDL-cholesterol levels.•APOE4- carriers with AD had functional harm with raising…”
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Methyl-CpG-Binding Protein (MBD) Family: Epigenomic Read-Outs Functions and Roles in Tumorigenesis and Psychiatric Diseases
Published in Journal of cellular biochemistry (01-01-2016)“…ABSTRACT Epigenetics is the study of the heritable changes on gene expression that are responsible for the regulation of development and that have an impact on…”
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