Search Results - "Chen, Delphine L"

Quantification of Lung PET Images: Challenges and Opportunities by Chen, Delphine L, Cheriyan, Joseph, Chilvers, Edwin R, Choudhury, Gourab, Coello, Christopher, Connell, Martin, Fisk, Marie, Groves, Ashley M, Gunn, Roger N, Holman, Beverley F, Hutton, Brian F, Lee, Sarah, MacNee, William, Mohan, Divya, Parr, David, Subramanian, Deepak, Tal-Singer, Ruth, Thielemans, Kris, van Beek, Edwin J R, Vass, Laurence, Wellen, Jeremy W, Wilkinson, Ian, Wilson, Frederick J

“…Millions of people are affected by respiratory diseases, leading to a significant health burden globally. Because of the current insufficient knowledge of the…”
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Glypican-3 targeted delivery of 89Zr and 90Y as a theranostic radionuclide platform for hepatocellular carcinoma by Labadie, Kevin P., Ludwig, Andrew D., Lehnert, Adrienne L., Hamlin, Donald K., Kenoyer, Aimee L., Sullivan, Kevin M., Daniel, Sara K., Mihailovic, Tara N., Sham, Jonathan G., Orozco, Johnnie J., Yeung, Raymond S., Chen, Delphine L., Wilbur, D. Scott, Miyaoka, Robert S., Park, James O.

“…Glypican-3 (GPC3) is a tumor associated antigen expressed by hepatocellular carcinoma (HCC) cells. This preclinical study evaluated the efficacy of a…”
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PET imaging approaches for inflammatory lung diseases: Current concepts and future directions by Chen, Delphine L, Schiebler, Mark L, Goo, Jin Mo, van Beek, Edwin J.R

“…Highlights • Positron emission tomography can provide molecular information inflammatory lung disease mechanisms and assess targeted treatment responses. •18…”
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Unmasking hidden Merkel cell carcinoma recurrences: Three illustrative cases of patients with rising viral oncoprotein antibody levels and challenge of requiring multi-modal imaging to detect clinical disease by Alexander, Nora A., Nghiem, Paul, Chen, Delphine L., Park, Song Y.

“…Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with a high risk of recurrence and metastasis. Regular surveillance through physical exams and…”
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The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study by Chen, Delphine L, Huang, Howard J, Byers, Derek E, Shifren, Adrian, Belikoff, Bryan, Engle, Jacquelyn T, Arentson, Elizabeth, Kemp, Debra, Phillips, Sharon, Scherrer, David E, Fujiwara, Hideji, Spayd, Katherine J, Brooks, Frank J, Pierce, Richard A, Castro, Mario, Isakow, Warren

“…Anti-inflammatory drug development efforts for lung disease have been hampered in part by the lack of noninvasive inflammation biomarkers and the limited…”
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Promising Advances for Imaging Lung Macrophage Recruitment by Chen, Delphine L

“…Chen examines the promising advances for imaging lung macrophage recruitment. Pulmonary hypertension (PH) contributes significantly to mortality and morbidity…”
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[18F]Fluorodeoxyglucose Positron Emission Tomography for Lung Antiinflammatory Response Evaluation by Chen, Delphine L, Bedient, Timothy J, Kozlowski, James, Rosenbluth, Daniel B, Isakow, Warren, Ferkol, Thomas W, Thomas, Betsy, Mintun, Mark A, Schuster, Daniel P, Walter, Michael J

“…Few noninvasive biomarkers for pulmonary inflammation are currently available that can assess the lung-specific response to antiinflammatory treatments…”
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PET Imaging of PARP Expression Using 18 F-Olaparib by Chen, Delphine L

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FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin by Chen, Delphine L, Rosenbluth, Daniel B, Mintun, Mark A, Schuster, Daniel P

“…1 Departments of Radiology and 2 Internal Medicine, Washington University School of Medicine, St. Louis, Missouri Submitted 11 November 2005 ; accepted in…”
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FDG PET Imaging in Cystic Fibrosis by Chen, Delphine L., MD, Atkinson, Jeffrey J., MD, Ferkol, Thomas W., MD

“…Cystic fibrosis (CF) is characterized by persistent neutrophilic lung inflammation that begins early in life and leads to an inexorable progressive loss of…”
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Prognostic Value of Early Fluorodeoxyglucose-Positron Emission Tomography Response Imaging and Peripheral Immunologic Biomarkers: Substudy of a Phase II Trial of Risk-Adaptive Chemoradiation for Unresectable Non-Small Cell Lung Cancer by Bowen, Stephen R., Hippe, Daniel S., Thomas, Hannah M., Sasidharan, Balukrishna, Lampe, Paul D., Baik, Christina S., Eaton, Keith D., Lee, Sylvia, Martins, Renato G., Santana-Davila, Rafael, Chen, Delphine L., Kinahan, Paul E., Miyaoka, Robert S., Vesselle, Hubert J., Houghton, A. McGarry, Rengan, Ramesh, Zeng, Jing

“…We sought to examine the prognostic value of fluorodeoxyglucose-positron emission tomography (PET) imaging during chemoradiation for unresectable non-small…”
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How Accurately does PSMA Inhibitor 18F-DCFPyL-PET-CT Image Prostate Cancer? by True, Lawrence D, Chen, Delphine L

“…Current techniques for imaging prostate cancer (CT, MRI, and PET agents F-fluorodeoxyglucose, C-choline, C-acetate, and F-fluciclovine) are limited in…”
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Positron Emission Tomography Imaging of Tumor Proliferation and DNA Repair by Shields, Anthony F, Chen, Delphine L

“…Positron emission tomography (PET) is an established tool for molecular imaging of cancers, and its role in diagnosis, staging, and phenotyping continues to…”
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Overview of positron emission tomography in functional imaging of the lungs for diffuse lung diseases by Gulhane, Avanti V, Chen, Delphine L

“…Positron emission tomography (PET) is a quantitative molecular imaging modality increasingly used to study pulmonary disease processes and drug effects on…”
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Imaging Pulmonary Inflammation by Scherer, Philip M, Chen, Delphine L

“…Lung inflammatory diseases contribute significantly to the socioeconomic burden of disease. Yet very few new, effective therapies for respiratory disease have…”
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Artificial intelligence in immunotherapy PET/SPECT imaging by McGale, Jeremy P., Chen, Delphine L., Trebeschi, Stefano, Farwell, Michael D., Wu, Anna M., Cutler, Cathy S., Schwartz, Lawrence H., Dercle, Laurent

“…Objective Immunotherapy has dramatically altered the therapeutic landscape for oncology, but more research is needed to identify patients who are likely to…”
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Concurrent pembrolizumab with AVD for untreated classic Hodgkin lymphoma by Lynch, Ryan C., Ujjani, Chaitra S., Poh, Christina, Warren, Edus H., Smith, Stephen D., Shadman, Mazyar, Till, Brian, Raghunathan, Vikram M., Alig, Stefan, Alizadeh, Ash A., Gulhane, Avanti, Chen, Delphine L., Tseng, Yolanda, Coye, Hilary, Shelby, Megan, Ottemiller, Susan, Keo, Sarith, Verni, Kaitlin, Du, Hongyan, Vandermeer, Jacquelin, Gaston, Ashley, Rasmussen, Heather, Martin, Paul, Marzbani, Edmond, Voutsinas, Jenna, Gopal, Ajay K.

“…•Concurrent APVD was safe and effective in untreated HL without clinically significant treatment delays.•CR rates by PET were lower than expected at all time…”
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Chemokine Receptor 2-targeted Molecular Imaging in Pulmonary Fibrosis. A Clinical Trial by Brody, Steven L, Gunsten, Sean P, Luehmann, Hannah P, Sultan, Debbie H, Hoelscher, Michelle, Heo, Gyu Seong, Pan, Jiehong, Koenitzer, Jeffrey R, Lee, Ethan C, Huang, Tao, Mpoy, Cedric, Guo, Shuchi, Laforest, Richard, Salter, Amber, Russell, Tonya D, Shifren, Adrian, Combadiere, Christophe, Lavine, Kory J, Kreisel, Daniel, Humphreys, Benjamin D, Rogers, Buck E, Gierada, David S, Byers, Derek E, Gropler, Robert J, Chen, Delphine L, Atkinson, Jeffrey J, Liu, Yongjian

“…Idiopathic pulmonary fibrosis (IPF) is a progressive inflammatory lung disease without effective molecular markers of disease activity or treatment responses…”
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PET of Poly (ADP-Ribose) Polymerase Activity in Cancer: Preclinical Assessment and First In-Human Studies by Michel, Loren S, Dyroff, Samantha, Brooks, Frank J, Spayd, Katherine J, Lim, Sora, Engle, Jacquelyn T, Phillips, Sharon, Tan, Benjamin, Wang-Gillam, Andrea, Bognar, Christopher, Chu, Wenhua, Zhou, Dong, Mach, Robert H, Laforest, Richard, Chen, Delphine L

“…Purpose To demonstrate that positron emission tomography (PET) with fluorine 18 ( F) fluorthanatrace (FTT) depicts activated poly (adenosine…”
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Long-range function of secreted small nucleolar RNAs that direct 2′-O-methylation by Rimer, Jamie M., Lee, Jiyeon, Holley, Christopher L., Crowder, Robert J., Chen, Delphine L., Hanson, Phyllis I., Ory, Daniel S., Schaffer, Jean E.

“…Small nucleolar RNAs (snoRNAs) are noncoding RNAs that guide chemical modifications of structural RNAs. Whereas snoRNAs primarily localize in the nucleolus,…”
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