Search Results - "Chen, Delin"

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression by Chen, Delin, Tavana, Omid, Chu, Bo, Erber, Luke, Chen, Yue, Baer, Richard, Gu, Wei

“…Although ARF can suppress tumor growth by activating p53 function, the mechanisms by which it suppresses tumor growth independently of p53 are not well…”
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iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4 by Chen, Delin, Chu, Bo, Yang, Xin, Liu, Zhaoqi, Jin, Ying, Kon, Ning, Rabadan, Raul, Jiang, Xuejun, Stockwell, Brent R., Gu, Wei

“…Here, we identify iPLA2β as a critical regulator for p53-driven ferroptosis upon reactive oxygen species (ROS)-induced stress. The calcium-independent…”
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Microblog sentiment analysis method using BTCBMA model in Spark big data environment by Wang, Qian, Chen, Delin

“…Microblogs are currently one of the most well-liked social platforms in China, and sentiment analysis of microblog texts can help further analyze the…”
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Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses by Chen, Delin, Shan, Jing, Zhu, Wei-Guo, Qin, Jun, Gu, Wei

“…ARF and p53 in oncogenic stress Of the known tumour suppressors, ARF and p53 are among the most relevant clinically, with p53 loss or inactivation found in…”
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GAS41 modulates ferroptosis by anchoring NRF2 on chromatin by Wang, Zhe, Yang, Xin, Chen, Delin, Liu, Yanqing, Li, Zhiming, Duan, Shoufu, Zhang, Zhiguo, Jiang, Xuejun, Stockwell, Brent R., Gu, Wei

“…YEATS domain-containing protein GAS41 is a histone reader and oncogene. Here, through genome-wide CRISPR-Cas9 screenings, we identify GAS41 as a repressor of…”
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Mammalian SIRT1 Represses Forkhead Transcription Factors by Motta, Maria Carla, Divecha, Nullin, Lemieux, Madeleine, Kamel, Christopher, Chen, Delin, Gu, Wei, Bultsma, Yvette, McBurney, Michael, Guarente, Leonard

“…The NAD-dependent deacetylase SIR2 and the forkhead transcription factor DAF-16 regulate lifespan in model organisms, such as yeast and C. elegans. Here we…”
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Total Synthesis and Structural Establishment/Revision of Antibiotics A54145 by Chen, Delin, Chow, Hoi Yee, Po, Kathy Hiu Laam, Ma, Wenjie, Leung, Emily Lok Yee, Sun, Zhenquan, Liu, Ming, Chen, Sheng, Li, Xuechen

“…A54145 is a family of antibacterial cyclic lipodepsipeptides structurally resembling daptomycin. Since its discovery in 1990, only the ambiguous structures of…”
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Differential Effects on ARF Stability by Normal versus Oncogenic Levels of c-Myc Expression by Chen, Delin, Kon, Ning, Zhong, Jiayun, Zhang, Pingzhao, Yu, Long, Gu, Wei

“…ARF suppresses aberrant cell growth upon c-Myc overexpression by activating p53 responses. Nevertheless, the precise mechanism by which ARF specifically…”
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Epidemiology, genetic characteristics, and association with meteorological factors of human metapneumovirus infection in children in southern China: A 10-year retrospective study by Ye, Hengming, Zhang, Shuqing, Zhang, Kexin, Li, Yizhe, Chen, Delin, Tan, Yongyao, Liang, Linyue, Liu, Minjie, Liang, Jingyao, An, Shu, Wu, Jueheng, Zhu, Xun, Li, Mengfeng, He, Zhenjian

“…•Human metapneumovirus (HMPV) is an important respiratory pathogen that causes acute respiratory tract infection in children ≤5 years old.•The prevalence peak…”
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Mono- versus Polyubiquitination: Differential Control of p53 Fate by Mdm2 by Li, Muyang, Brooks, Christopher L., Wu-Baer, Foon, Chen, Delin, Baer, Richard, Gu, Wei

“…Although Mdm2-mediated ubiquitination is essential for both degradation and nuclear export of p53, the molecular basis for the differential effects of Mdm2…”
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Deacetylation of p53 modulates its effect on cell growth and apoptosis by Gu, Wei, Luo, Jianyuan, Su, Fei, Chen, Delin, Shiloh, Ariel

“…The p53 tumour suppressor is a transcriptional factor whose activity is modulated by protein stability and post-translational modifications including…”
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Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization by Gu, Wei, Li, Muyang, Chen, Delin, Shiloh, Ariel, Luo, Jianyuan, Nikolaev, Anatoly Y, Qin, Jun

“…The p53 tumour suppressor is a short-lived protein that is maintained at low levels in normal cells by Mdm2-mediated ubiquitination and subsequent proteolysis…”
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ARF-NRF2: A new checkpoint for oxidative stress responses? by Chen, Delin, Tavana, Omid, Gu, Wei

“…NRF2 (nuclear factor erythroid 2-related factor 2) is a transcription factor which plays a major role in oxidative stress responses by regulating antioxidant…”
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Reactivating the ARF-p53 axis in AML cells by targeting ULF by Chen, Delin, Yoon, Jong-Bok, Gu, Wei

“…The tumor suppressor ARF plays an essential role in the cellular response to oncogenic stress mainly through activation of p53. Nucleophosmin (NPM), a…”
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Effects of raw material extrusion and steam conditioning on feed pellet quality and nutrient digestibility of growing meat rabbits by Liao, Kuoyao, Cai, Jingyi, Shi, Zhujun, Tian, Gang, Yan, Dong, Chen, Delin

“…This study was conducted to investigate the effects of raw material extrusion and steam conditioning on feed pellet quality and nutrient digestibility of…”
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Influence of microtextured parameters of dry gas sealing rings on tribological performance by Chen, Delin

“…Purpose This study aims to research the influence mechanism of microtextured geometric parameters of dry gas seal end face on the tribological behavior under…”
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Characterization of ARF-BP1/HUWE1 interactions with CTCF, MYC, ARF and p53 in MYC-driven B cell neoplasms by Qi, Chen-Feng, Kim, Yong-Soo, Xiang, Shao, Abdullaev, Ziedulla, Torrey, Ted A, Janz, Siegfried, Kovalchuk, Alexander L, Sun, Jiafang, Chen, Delin, Cho, William C, Gu, Wei, Morse, 3rd, Herbert C

“…Transcriptional activation of MYC is a hallmark of many B cell lineage neoplasms. MYC provides a constitutive proliferative signal but can also initiate…”
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Comparison Study Between Observation and Simulation for Sea Fog over the Yellow Sea in May 2009 by Fu, Dan, Wang, Shuai, Chen, Delin, Pang, Huaji, Li, Pengyuan

“…In this paper, almost all available observational data and the latest 6.0 version of Regional Atmospheric Modeling System （RAMS） model were employed to…”
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ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway by Chu, Bo, Kon, Ning, Chen, Delin, Li, Tongyuan, Liu, Tong, Jiang, Le, Song, Shujuan, Tavana, Omid, Gu, Wei

“…It is well established that ferroptosis is primarily controlled by glutathione peroxidase 4 (GPX4). Surprisingly, we observed that p53 activation modulates…”
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Photoredox-catalyzed self-dimerization and cross-addition as well as Zn(OTf)2-mediated nucleophile coupling: A novel route to structurally diverse 2,2-disubstituted indolin-3-ones by Chen, Delin, Xiao, Jiayao, Liu, Ketong, Chen, Zhitao

“…An efficient protocol for the synthesis of 2,2-disubstituted indolin-3-ones from both 2-aryl and 2-alkyl indoles via photoredox-catalyzed self-dimerization and…”
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