Search Results - "Chen, Daniel G"

T cell receptor sequences are the dominant factor contributing to the phenotype of CD8+ T cells with specificities against immunogenic viral antigens by Chen, Daniel G., Xie, Jingyi, Su, Yapeng, Heath, James R.

“…Antigen-specific CD8+ T cells mediate pathogen clearance. T cell phenotype is influenced by T cell receptor (TCR) sequences and environmental signals…”
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T cell receptor sequences are the dominant factor contributing to the phenotype of CD8+ T cells with specificities against immunogenic viral antigens by Chen, Daniel G., Xie, Jingyi, Su, Yapeng, Heath, James R.

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Artificial image objects for classification of breast cancer biomarkers with transcriptome sequencing data and convolutional neural network algorithms by Chen, Xiangning, Chen, Daniel G, Zhao, Zhongming, Balko, Justin M, Chen, Jingchun

“…Transcriptome sequencing has been broadly available in clinical studies. However, it remains a challenge to utilize these data effectively for clinical…”
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Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer by Chen, Daniel G., Xie, Jingyi, Choi, Jongchan, Ng, Rachel H., Zhang, Rongyu, Li, Sarah, Edmark, Rick, Zheng, Hong, Solomon, Ben, Campbell, Katie M., Medina, Egmidio, Ribas, Antoni, Khatri, Purvesh, Lanier, Lewis L., Mease, Philip J., Goldman, Jason D., Su, Yapeng, Heath, James R.

“…Infection, autoimmunity, and cancer are principal human health challenges of the 21st century. Often regarded as distinct ends of the immunological spectrum,…”
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Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice by Feng, Wenchao, Liu, Mengyao, Chen, Daniel G, Yiu, Rossana, Fang, Ferric C, Lei, Benfang

“…Group A Streptococcus (GAS) causes diverse infections ranging from common pharyngitis to rare severe invasive infections. Invasive GAS isolates can have…”
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The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids by Zufferey, Rachel, Pirani, Karim, Cheung-See-Kit, Melanie, Lee, Sungsu, Williams, Tyler A, Chen, Daniel G, Hossain, Md Faruk

“…Glycerophospholipids are the most abundant constituents of biological membranes in Trypanosoma brucei, which causes sleeping sickness in humans and nagana in…”
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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis by Chour, William, Choi, Jongchan, Xie, Jingyi, Chaffee, Mary E., Schmitt, Thomas M., Finton, Kathryn, DeLucia, Diana C., Xu, Alexander M., Su, Yapeng, Chen, Daniel G., Zhang, Rongyu, Yuan, Dan, Hong, Sunga, Ng, Alphonsus H. C., Butler, Jonah Z., Edmark, Rick A., Jones, Lesley C., Murray, Kim M., Peng, Songming, Li, Guideng, Strong, Roland K., Lee, John K., Goldman, Jason D., Greenberg, Philip D., Heath, James R.

“…The discovery and characterization of antigen-specific CD8 + T cell clonotypes typically involves the labor-intensive synthesis and construction of peptide-MHC…”
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Correction: Acute cholecystitis, obesity, and steatohepatitis constitute the lethal triad for bile duct injury (BDI) during laparoscopic cholecystectomy by Gutierrez, Joseph V., Chen, Daniel G., Yheulon, Christopher G., Mangieri, Christopher W.

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Acute cholecystitis, obesity, and steatohepatitis constitute the lethal triad for bile duct injury (BDI) during laparoscopic cholecystectomy by Gutierrez, Joseph V., Chen, Daniel G., Yheulon, Christopher G., Mangieri, Christopher W.

“…Objective The most feared complication during laparoscopic cholecystectomy remains a bile duct injury (BDI). Accurately risk-stratifying patients for a BDI…”
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Artificial image objects for classification of schizophrenia with GWAS-selected SNVs and convolutional neural network by Chen, Xiangning, Chen, Daniel G., Zhao, Zhongming, Zhan, Justin, Ji, Changrong, Chen, Jingchun

“…In this article, we propose a new approach to analyze large genomics data. We considered individual genetic variants as pixels in an image and transformed a…”
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The Glycerol-3-Phosphate Acyltransferase TbGAT is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei by Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Cheung-See-Kit, Melanie, Lee, Sungsu, Chen, Daniel G., Zufferey, Rachel

“…Glycerolipids are the main constituents of biological membranes in Trypanosoma brucei, which causes sleeping sickness in humans. Importantly, they occur as a…”
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Multiple early factors anticipate post-acute COVID-19 sequelae by Su, Yapeng, Yuan, Dan, Chen, Daniel G., Ng, Rachel H., Wang, Kai, Choi, Jongchan, Li, Sarah, Hong, Sunga, Zhang, Rongyu, Xie, Jingyi, Kornilov, Sergey A., Scherler, Kelsey, Pavlovitch-Bedzyk, Ana Jimena, Dong, Shen, Lausted, Christopher, Lee, Inyoul, Fallen, Shannon, Dai, Chengzhen L., Baloni, Priyanka, Smith, Brett, Duvvuri, Venkata R., Anderson, Kristin G., Li, Jing, Yang, Fan, Duncombe, Caroline J., McCulloch, Denise J., Rostomily, Clifford, Troisch, Pamela, Zhou, Jing, Mackay, Sean, DeGottardi, Quinn, May, Damon H., Taniguchi, Ruth, Gittelman, Rachel M., Klinger, Mark, Snyder, Thomas M., Roper, Ryan, Wojciechowska, Gladys, Murray, Kim, Edmark, Rick, Evans, Simon, Jones, Lesley, Zhou, Yong, Rowen, Lee, Liu, Rachel, Chour, William, Algren, Heather A., Berrington, William R., Wallick, Julie A., Cochran, Rebecca A., Micikas, Mary E., Wrin, Terri, Petropoulos, Christos J., Cole, Hunter R., Fischer, Trevan D., Wei, Wei, Hoon, Dave S.B., Price, Nathan D., Subramanian, Naeha, Hill, Joshua A., Hadlock, Jennifer, Magis, Andrew T., Ribas, Antoni, Lanier, Lewis L., Boyd, Scott D., Bluestone, Jeffrey A., Chu, Helen, Hood, Leroy, Gottardo, Raphael, Greenberg, Philip D., Davis, Mark M., Goldman, Jason D., Heath, James R.

“…Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk factors for PASC and their biological associations are…”
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The Glycerol‐3‐Phosphate Acyltransferase Tb GAT is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei by Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Cheung‐See‐Kit, Melanie, Lee, Sungsu, Chen, Daniel G., Zufferey, Rachel

“…Glycerolipids are the main constituents of biological membranes in Trypanosoma brucei , which causes sleeping sickness in humans. Importantly, they occur as a…”
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Abstract 6550: Biopsy analysis of trial S1616: Ipilimumab plus nivolumab versus ipilimumab alone in patients with anti-PD-1 refractory melanoma by Campbell, Katie M., Bustami, Zaid, Chen, Daniel G., Medina, Egmidio, Gonzalez, Cynthia R., Aldeen, Nataly Naser, Baselga-Carretero, Ignacio, Vega-Crespo, Agustin, Maxey, Jessica, Chen, Jia M., Kuklinski, Lawrence F., Kendra, Kari L., Chmielowski, Bartosz, Truong, Thach-Giao, Khushalani, Nikhil I., Collichio, Frances, Ikeguchi, Alexandra, Victor, Adrienne I., Margolin, Kim, Sosman, Jeffrey A., Patel, Sapna P., Hu-Lieskovan, Siwen, Moon, James, Bellasea, Shay, Wells, Daniel K., Spencer, Christine N., Thompson, Marshall A., Wu, Michael, Scumpia, Philip O., VanderWalde, Ari, Ribas, Antoni

“…Background: The phase II randomized trial S1616 (NCT03033576) showed that patients with melanoma refractory to anti-PD-1-based therapy had improved progression…”
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Evolving procedural options for the treatment of obesity by Tatarian, Talar, Rona, Kais A., Shin, Daniel H., Chen, Daniel G., Ducoin, Christopher G., Moore, Rachel L., Brunaldi, Vitor O., Galvão-Neto, Manoel, Ardila-Gatas, Jessica, Docimo, Salvatore, Hourneax de Moura, Diogo T., Jirapinyo, Pichamol, Thompson, Christopher C., Billy, Helmuth T., Roslin, Mitchell S., Borden, Billie, Zarabi, Sharon, Sweigert, Patrick J., Chand, Bipan, Pryor, Aurora D.

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In Brief by Tatarian, Talar, Rona, Kais A., Shin, Daniel H., Chen, Daniel G., Ducoin, Christopher G., Moore, Rachel L., Brunaldi, Vitor O., Galvão-Neto, Manoel, Ardila-Gatas, Jessica, Docimo, Salvatore, Hourneax de Moura, Diogo T., Jirapinyo, Pichamol, Thompson, Christopher C., Billy, Helmuth T., Roslin, Mitchell S., Borden, Billie, Zarabi, Sharon, Sweigert, Patrick J., Chand, Bipan, Pryor, Aurora D.

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In Brief by Tatarian, Talar, Rona, Kais A., Shin, Daniel H., Chen, Daniel G., Ducoin, Christopher G., Moore, Rachel L., Brunaldi, Vitor O., Galvão-Neto, Manoel, Ardila-Gatas, Jessica, Docimo, Salvatore, Hourneax de Moura, Diogo T., Jirapinyo, Pichamol, Thompson, Christopher C., Billy, Helmuth T., Roslin, Mitchell S., Borden, Billie, Zarabi, Sharon, Sweigert, Patrick J., Chand, Bipan, Pryor, Aurora D.

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Celcomen: spatial causal disentanglement for single-cell and tissue perturbation modeling by Megas, Stathis, Chen, Daniel G, Polanski, Krzysztof, Eliasof, Moshe, Schonlieb, Carola-Bibiane, Teichmann, Sarah A

“…Celcomen leverages a mathematical causality framework to disentangle intra- and inter- cellular gene regulation programs in spatial transcriptomics and…”
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Catalytic dechlorination and detoxification of 1-（2-chlorophenyl） ethanol by Pd/Fe by Hong-yi ZHOU Shang-chen WANG G. Daniel SHENG

“…1-（2-chlorophenyl） ethanol （CPE） is of health and environmental concern due to its toxicity and its use as an intermediate in pharmaceutical manufacturing. The…”
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