Search Results - "Chen, Dahu"

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis by Yao, Fan, Deng, Yalan, Zhao, Yang, Mei, Ying, Zhang, Yilei, Liu, Xiaoguang, Martinez, Consuelo, Su, Xiaohua, Rosato, Roberto R., Teng, Hongqi, Hang, Qinglei, Yap, Shannon, Chen, Dahu, Wang, Yumeng, Chen, Mei-Ju May, Zhang, Mutian, Liang, Han, Xie, Dong, Chen, Xin, Zhu, Hao, Chang, Jenny C., You, M. James, Sun, Yutong, Gan, Boyi, Ma, Li

“…The growing knowledge of ferroptosis has suggested the role and therapeutic potential of ferroptosis in cancer, but has not been translated into effective…”
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Hsa-miR-22-3p inhibits liver cancer cell EMT and cell migration/ invasion by indirectly regulating SPRY2 by Cui, Shuaishuai, Chen, Yuanyuan, Guo, Yunfei, Wang, Xing, Chen, Dahu

“…The general mechanism for microRNAs to play biological function is through their inhibition on the expression of their target genes. In cancer, microRNAs may…”
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grape bHLH transcription factor gene, VvbHLH1, increases the accumulation of flavonoids and enhances salt and drought tolerance in transgenic Arabidopsis thaliana by Wang, Feibing, Hong Zhu, Dahu Chen, Zhenjun Li, Rihe Peng, Quanhong Yao

“…In plants, transcriptional regulation is the most important tool for modulating flavonoid biosynthesis. The basic helix-loop-helix transcription factors are…”
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ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1 by Zhang, Peijing, Wei, Yongkun, Wang, Li, Debeb, Bisrat G., Yuan, Yuan, Zhang, Jinsong, Yuan, Jingsong, Wang, Min, Chen, Dahu, Sun, Yutong, Woodward, Wendy A., Liu, Yongqing, Dean, Douglas C., Liang, Han, Hu, Ye, Ang, K. Kian, Hung, Mien-Chie, Chen, Junjie, Ma, Li

“…Epithelial–mesenchymal transition (EMT) is associated with characteristics of breast cancer stem cells, including chemoresistance and radioresistance. However,…”
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USP4 promotes the proliferation and glucose metabolism of gastric cancer cells by upregulating PKM2 by Chen, Yuanyuan, Guo, Yunfei, Yuan, Mei, Guo, Song, Cui, Shuaishuai, Chen, Dahu

“…Background The pyruvate kinase enzyme PKM2 catalyzes the final step in glycolysis and converts phosphoenolpyruvate (PEP) to pyruvate. PKM2 is often…”
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Deubiquitylation and stabilization of PTEN by USP13 by Zhang, Jinsong, Zhang, Peijing, Wei, Yongkun, Piao, Hai-long, Wang, Wenqi, Maddika, Subbareddy, Wang, Min, Chen, Dahu, Sun, Yutong, Hung, Mien-Chie, Chen, Junjie, Ma, Li

“…The tumour suppressor PTEN is frequently lost in human cancers. In addition to gene mutations and deletions, recent studies have revealed the importance of…”
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Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways by Kim, Jongchan, Siverly, Ashley N, Chen, Dahu, Wang, Min, Yuan, Yuan, Wang, Yumeng, Lee, Hyemin, Zhang, Jinsong, Muller, William J, Liang, Han, Gan, Boyi, Yang, Xianbin, Sun, Yutong, You, M James, Ma, Li

“…The invasive and metastatic properties of many human tumors have been associated with upregulation of the miRNA miR-10b, but its functional contributions in…”
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Ubiquitin specific peptidases and prostate cancer by Guo, Yunfei, Cui, Shuaishuai, Chen, Yuanyuan, Guo, Song, Chen, Dahu

“…Protein ubiquitination is an important post-translational modification mechanism, which regulates protein stability and activity. The ubiquitination of…”
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miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion by Chen, Dahu, Sun, Yutong, Yuan, Yuan, Han, Zhenbo, Zhang, Peijing, Zhang, Jinsong, You, M James, Teruya-Feldstein, Julie, Wang, Min, Gupta, Sumeet, Hung, Mien-Chie, Liang, Han, Ma, Li

“…Whether epithelial-mesenchymal transition (EMT) is always linked to increased tumorigenicity is controversial. Through microRNA (miRNA) expression profiling of…”
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The role of CEMIP in cancers and its transcriptional and post-transcriptional regulation by Guo, Song, Guo, Yunfei, Chen, Yuanyuan, Cui, Shuaishuai, Zhang, Chunmei, Chen, Dahu

“…CEMIP is a protein known for inducing cell migration and binding to hyaluronic acid. Functioning as a hyaluronidase, CEMIP primarily facilitates the breakdown…”
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Primary Non-Inversion Shallow Tillage Versus Moldboard Plowing Prior to Growing Potatoes: Short-Term Impacts on Potato Yield and Soil Properties in Eastern Canada by Nyiraneza, Judith, Fraser, Tandra D., Murnaghan, Danielle, Matheson, Jessica, Arnold, Stephanie, Stiles, Kyra, Chen, Dahu, Peters, Rick, Khakbazan, Mohammad, Barrett, Ryan

“…Potato ( Solanum tuberosum L.) production often requires intensive tillage with the moldboard plow (MP), which involves deeper soil tillage and turning of the…”
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Effect of Biofumigation on Population Densities of Pratylenchus spp. and Verticillium spp. and Potato Yield in Eastern Canada by Chen, Dahu, Zebarth, Bernie J., Goyer, Claudia, Comeau, Louis-Pierre, Nahar, Kamrun, Dixon, Tom

“…Biofumigation has been proposed as an alternative to soil fumigation to manage soil-borne diseases including potato early dying disease complex (PED). This…”
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Prevalence of Verticillium spp. and Pratylenchus spp. in Commercial Potato Fields in Atlantic Canada by Chen, Dahu, Barrett, Ryan, Mimee, Benjamin, Arseneault, Tanya, Comeau, Louis-Pierre, Nahar, Kamrun, Jimenez, Sebastian Ibarra, Zebarth, Bernie J.

“…A survey of New Brunswick (NB) and Prince Edward Island (PEI) potato fields in crop rotation phase prior to potato production was conducted in fall (October…”
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A Simple and Efficient Inoculation Method for Fusarium Dry Rot Evaluations in Potatoes by Chen, Dahu, Nahar, Kamrun, Bizimungu, Benoit, Soucy, Sylvia, Peters, Rick D., De Koeyer, David, Dickison, Virginia

“…Fusarium dry rot (FDR), caused by Fusarium species is an important potato disease world-wide and causes post-harvest rotting and seed-piece decay after…”
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Cyanidin-3- O -glucoside inhibits epithelial-to-mesenchymal transition, and migration and invasion of breast cancer cells by upregulating KLF4 by Chen, Dahu, Yuan, Mei, Ye, Qin, Wang, Xing, Xu, Jing, Shi, Guangyi, Hu, Zhaodi

“…Anthocyanins (ACNs) are capable of suppressing breast cancer growth; however, investigation on the effect and mechanism of ACNs on epithelial-to-mesenchymal…”
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Improving Soil Quality and Potato Productivity with Manure and High-Residue Cover Crops in Eastern Canada by Nyiraneza, Judith, Chen, Dahu, Fraser, Tandra, Comeau, Louis-Pierre

“…Under intensive low residue agricultural systems, such as those involving potato ( L.)-based systems, stagnant crop yields and declining soil health and…”
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Increased Expression of Enzymes of Triglyceride Synthesis Is Essential for the Development of Hepatic Steatosis by Jin, Jingling, Iakova, Polina, Breaux, Meghan, Sullivan, Emily, Jawanmardi, Nicole, Chen, Dahu, Jiang, Yanjun, Medrano, Estela M., Timchenko, Nikolai A.

“…Molecular mechanisms underpinning nonalcoholic fatty liver disease (NAFLD) are not well understood. The earliest step of NAFLD is hepatic steatosis, which is…”
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A Genome Resource for 192 Verticillium dahliae Isolates Infecting Potatoes Across Canada by Arseneault, Tanya, Lafond-Lapalme, Joël, Gonzalez, Chary Esteban Quinche, Jordan, Katerina S., Yevtushenko, Dmytro, Barrett, Ryan, Van der Heyden, Hervé, Chen, Dahu, Tenuta, Mario, Mimee, Benjamin

“…Verticillium dahliae is an important soilborne pathogen causing Verticillium wilt. It is also the primary causal agent of potato early dying, a disease complex…”
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SKI promotes Smad3 linker phosphorylations associated with the tumor-promoting trait of TGF-β by Lin, Qiushi, Chen, Dahu, Timchenko, Nikolai A., Medrano, Estela E.

“…The transcriptional co-regulator SKI is a potent inhibitor of TGF-β-growth inhibitory signals. SKI binds to receptor-activated Smads in the nucleus, forming…”
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SKI knockdown inhibits human melanoma tumor growth in vivo by Chen, Dahu, Lin, Qiushi, Box, Neil, Roop, Dennis, Ishii, Shunsuke, Matsuzaki, Koichi, Fan, Tao, Hornyak, Thomas J., Reed, Jon A, Stavnezer, Ed, Timchenko, Nikolai A., Medrano, Estela E.

“…Summary The SKI protein represses the TGF‐β tumor suppressor pathway by associating with the Smad transcription factors. SKI is upregulated in human malignant…”
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