Search Results - "Chen, Connie"

Blended Care-Cognitive Behavioral Therapy for Depression and Anxiety in Real-World Settings: Pragmatic Retrospective Study by Lungu, Anita, Jun, Janie Jihee, Azarmanesh, Okhtay, Leykin, Yan, Chen, Connie E-Jean

“…The past few decades saw considerable advances in research and dissemination of evidence-based psychotherapies, yet available treatment resources are not able…”
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Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy by Winthrop, Kevin L., Curtis, Jeffrey R., Lindsey, Stephen, Tanaka, Yoshiya, Yamaoka, Kunihiro, Valdez, Hernan, Hirose, Tomohiro, Nduaka, Chudy I., Wang, Lisy, Mendelsohn, Alan M., Fan, Haiyun, Chen, Connie, Bananis, Eustratios

“…Objective Patients with rheumatoid arthritis (RA) are at increased risk of herpes zoster (HZ), and the risk appears to be increased in patients treated with…”
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Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing by Marchetti, Francesco, Cardoso, Renato, Chen, Connie L., Douglas, George R., Elloway, Joanne, Escobar, Patricia A., Harper Jr, Tod, Heflich, Robert H., Kidd, Darren, Lynch, Anthony M., Myers, Meagan B., Parsons, Barbara L., Salk, Jesse J., Settivari, Raja S., Smith-Roe, Stephanie L., Witt, Kristine L., Yauk, Carole, Young, Robert R., Zhang, Shaofei, Minocherhomji, Sheroy

“…Error-corrected next-generation sequencing (ecNGS) is an emerging technology with the potential to revolutionize the field of genetic toxicology. Here, we…”
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SOX2–LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors by Cimadamore, Flavio, Amador-Arjona, Alejandro, Chen, Connie, Huang, Chun-Teng, Terskikh, Alexey V

“…The transcription factor SRY (sex-determining region)-box 2 (SOX2) is an important functional marker of neural precursor cells (NPCs) and plays a critical role…”
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Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial by Motzer, Robert J, Dr, Escudier, Bernard, MD, Tomczak, Piotr, MD, Hutson, Thomas E, DO, Michaelson, M Dror, MD, Negrier, Sylvie, Prof, Oudard, Stephane, Prof, Gore, Martin E, Prof, Tarazi, Jamal, MD, Hariharan, Subramanian, MD, Chen, Connie, PharmD, Rosbrook, Brad, MS, Kim, Sinil, MD, Rini, Brian I, MD

“…Summary Background In a phase 3 trial comparing the efficacy and safety of axitinib versus sorafenib as second-line treatment for metastatic renal cell…”
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Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial by Hutson, Thomas E, Prof, Lesovoy, Vladimir, Prof, Al-Shukri, Salman, Prof, Stus, Viktor P, Prof, Lipatov, Oleg N, Prof, Bair, Angel H, PhD, Rosbrook, Brad, MS, Chen, Connie, PharmD, Kim, Sinil, MD, Vogelzang, Nicholas J, Prof

“…Summary Background In previous clinical trials of patients with metastatic renal-cell carcinoma, patients treated with axitinib as second-line therapy had…”
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Release of extracellular ATP by bacteria during growth by Mempin, Roberto, Tran, Helen, Chen, Connie, Gong, Hao, Kim Ho, Katharina, Lu, Sangwei

“…Adenosine triphosphate (ATP) is used as an intracellular energy source by all living organisms. It plays a central role in the respiration and metabolism, and…”
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Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial by Rini, Brian I, Dr, Escudier, Bernard, MD, Tomczak, Piotr, MD, Kaprin, Andrey, Prof, Szczylik, Cezary, MD, Hutson, Thomas E, DO, Michaelson, M Dror, MD, Gorbunova, Vera A, Prof, Gore, Martin E, Prof, Rusakov, Igor G, Prof, Negrier, Sylvie, Prof, Ou, Yen-Chuan, Prof, Castellano, Daniel, MD, Lim, Ho Yeong, Prof, Uemura, Hirotsugu, Prof, Tarazi, Jamal, MD, Cella, David, PhD, Chen, Connie, PharmD, Rosbrook, Brad, MS, Kim, Sinil, MD, Motzer, Robert J, MD

“…Summary Background The treatment of advanced renal cell carcinoma has been revolutionised by targeted therapy with drugs that block angiogenesis. So far, no…”
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Oxidative Stress in Developmental Origins of Disease: Teratogenesis, Neurodevelopmental Deficits, and Cancer by Wells, Peter G., McCallum, Gordon P., Chen, Connie S., Henderson, Jeffrey T., Lee, Crystal J. J., Perstin, Julia, Preston, Thomas J., Wiley, Michael J., Wong, Andrea W.

“…In the developing embryo and fetus, endogenous or xenobiotic-enhanced formation of reactive oxygen species (ROS) like hydroxyl radicals may adversely alter…”
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Ontogeny and Cross-species Comparison of Pathways Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Neonates (Review): Kidney by Bueters, Ruud, Bael, An, Gasthuys, Elke, Chen, Connie, Schreuder, Michiel F, Frazier, Kendall S

“…The kidneys play an important role in many processes, including urine formation, water conservation, acid-base equilibrium, and elimination of waste. The…”
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Effectiveness of a Cognitive Behavioral Coaching Program Delivered via Video in Real World Settings by Lungu, Anita, Boone, Matthew S, Chen, Shih Yin, Chen, Connie E, Walser, Robyn D

“…Many employees experience high levels of stress in the workplace, which negatively impact their productivity and well-being. Effective stress management…”
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A large-scale evaluation of therapeutic alliance and symptom trajectories of depression and anxiety in blended care therapy by Wu, Monica S, Wickham, Robert E, Chen, Shih-Yin, Varra, Alethea, Chen, Connie, Lungu, Anita

“…This study sought to conduct a large-scale examination ( N = 14,951) into the associations between therapeutic alliance and anxiety and depression symptom…”
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Lymphoma in the Tofacitinib Rheumatoid Arthritis Clinical Development Program by Mariette, Xavier, Chen, Connie, Biswas, Pinaki, Kwok, Kenneth, Boy, Mary G.

“…Objective Tofacitinib is an oral JAK inhibitor indicated for the treatment of rheumatoid arthritis (RA). We characterized lymphoma events in the tofacitinib RA…”
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Effects of a 12-week mHealth program on peak VO2 and physical activity patterns after completing cardiac rehabilitation: A randomized controlled trial by Duscha, Brian D., Piner, Lucy W., Patel, Mahesh P., Craig, Karen P., Brady, Morgan, McGarrah, Robert W., Chen, Connie, Kraus, William E.

“…Site-based cardiac rehabilitation (CR) provides supervised exercise, education and motivation for patients. Graduates of CR have improved exercise tolerance…”
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Long-term safety of tofacitinib up to 9.5 years: a comprehensive integrated analysis of the rheumatoid arthritis clinical development programme by Cohen, Stanley B, Tanaka, Yoshiya, Mariette, Xavier, Curtis, Jeffrey R, Lee, Eun Bong, Nash, Peter, Winthrop, Kevin L, Charles-Schoeman, Christina, Wang, Lisy, Chen, Connie, Kwok, Kenneth, Biswas, Pinaki, Shapiro, Andrea, Madsen, Ann, Wollenhaupt, Jürgen

“…ObjectiveTofacitinib is an oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid arthritis (RA). We report the largest integrated safety analysis…”
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Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron by Chorley, Brian N, Ellinger-Ziegelbauer, Heidrun, Tackett, Michael, Simutis, Frank J, Harrill, Alison H, McDuffie, James, Atabakhsh, Elnaz, Nassirpour, Rounak, Whiteley, Laurence O, Léonard, Jean-François, Carswell, Gleta K, Harpur, Ernie, Chen, Connie L, Gautier, Jean-Charles

“…Abstract Drug-induced kidney injury (DIKI) is a major concern in both drug development and clinical practice. There is an unmet need for biomarkers of…”
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Chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer survivors: a comparison of patient-reported outcomes and quantitative sensory testing by Zhi, W. Iris, Chen, Patricia, Kwon, Alice, Chen, Connie, Harte, Steven E., Piulson, Lauren, Li, Susan, Patil, Sujata, Mao, Jun J., Bao, Ting

“…Purpose CIPN is a common, debilitating, and dose-limiting side effect of chemotherapy. Here, we describe characteristics of patients with CIPN using both…”
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Real-world study of overall survival with palbociclib plus aromatase inhibitor in HR+/HER2− metastatic breast cancer by Rugo, Hope S., Brufsky, Adam, Liu, Xianchen, Li, Benjamin, McRoy, Lynn, Chen, Connie, Layman, Rachel M., Cristofanilli, Massimo, Torres, Mylin A., Curigliano, Giuseppe, Finn, Richard S., DeMichele, Angela

“…Data on real-world effectiveness of cyclin-dependent kinase 4/6 inhibitor combination therapy versus endocrine therapy alone are limited. The Flatiron Health…”
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Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1 by Mori, Hidetoshi, Lo, Alvin T, Inman, Jamie L, Alcaraz, Jordi, Ghajar, Cyrus M, Mott, Joni D, Nelson, Celeste M, Chen, Connie S, Zhang, Hui, Bascom, Jamie L, Seiki, Motoharu, Bissell, Mina J

“…Epithelial cell invasion through the extracellular matrix (ECM) is a crucial step in branching morphogenesis. The mechanisms by which the mammary epithelium…”
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Walk-in clinics versus physician offices and emergency rooms for urgent care and chronic disease management by Chen, Connie E, Chen, Christopher T, Hu, Jia, Mehrotra, Ateev

“…Walk-in clinics are growing in popularity around the world as a substitute for traditional medical care delivered in physician offices and emergency rooms, but…”
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