Search Results - "Chen, Chuanli"
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Radiomics signature of computed tomography imaging for prediction of survival and chemotherapeutic benefits in gastric cancer
Published in EBioMedicine (01-10-2018)“…To develop and validate a radiomics signature for the prediction of gastric cancer (GC) survival and chemotherapeutic benefits. In this multicenter…”
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2
Noninvasive imaging of the tumor immune microenvironment correlates with response to immunotherapy in gastric cancer
Published in Nature communications (30-08-2022)“…The tumor immune microenvironment (TIME) is associated with tumor prognosis and immunotherapy response. Here we develop and validate a CT-based radiomics score…”
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3
Biology-guided deep learning predicts prognosis and cancer immunotherapy response
Published in Nature communications (23-08-2023)“…Substantial progress has been made in using deep learning for cancer detection and diagnosis in medical images. Yet, there is limited success on prediction of…”
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4
Myosin light chain kinase mediates intestinal barrier disruption following burn injury
Published in PloS one (18-04-2012)“…Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC)…”
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Radiomics Signature on Computed Tomography Imaging: Association With Lymph Node Metastasis in Patients With Gastric Cancer
Published in Frontiers in oncology (26-04-2019)“…To evaluate whether radiomic feature-based computed tomography (CT) imaging signatures allow prediction of lymph node (LN) metastasis in gastric cancer (GC)…”
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PAK6 promotes homologous-recombination to enhance chemoresistance to oxaliplatin through ATR/CHK1 signaling in gastric cancer
Published in Cell death & disease (28-07-2022)“…Chemoresistance remains the primary challenge of clinical treatment of gastric cancer (GC), making the biomarkers of chemoresistance crucial for treatment…”
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Prevalence and risk factors of stroke in high-altitude areas: a systematic review and meta-analysis
Published in BMJ open (21-09-2023)“…Objective The primary objective of this study is to investigate the prevalence and risk factors of stroke in high-altitude areas through a comprehensive…”
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Radiomics Nomogram for Prediction of Peritoneal Metastasis in Patients With Gastric Cancer
Published in Frontiers in oncology (20-08-2020)“…Objective: The aim of this study is to evaluate whether radiomics imaging signatures based on computed tomography (CT) could predict peritoneal metastasis (PM)…”
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Radiographical assessment of tumour stroma and treatment outcomes using deep learning: a retrospective, multicohort study
Published in The Lancet. Digital health (01-06-2021)“…The tumour stroma microenvironment plays an important part in disease progression and its composition can influence treatment response and outcomes…”
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Non-invasive CT imaging biomarker to predict immunotherapy response in gastric cancer: a multicenter study
Published in Journal for immunotherapy of cancer (21-11-2023)“…BackgroundDespite remarkable benefits have been provided by immune checkpoint inhibitors in gastric cancer (GC), predictions of treatment response and…”
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Recent advances of propiolic acids in organic reactions
Published in Tetrahedron letters (23-01-2020)“…[Display omitted] •Acids as nucleophiles.•Electrophilic alkynes.•Decarboxylative coupling.•Decarboxylative addition.•Electrophilic acids. Herein, recent…”
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Development and Validation of a Deep Learning CT Signature to Predict Survival and Chemotherapy Benefit in Gastric Cancer: A Multicenter, Retrospective Study
Published in Annals of surgery (01-12-2021)“…OBJECTIVE:We aimed to develop a deep learning-based signature to predict prognosis and benefit from adjuvant chemotherapy using preoperative computed…”
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Cancer immunotherapy response prediction from multi-modal clinical and image data using semi-supervised deep learning
Published in Radiotherapy and oncology (01-09-2023)“…•We present a deep learning model by using multi-modal clinical and image data for predicting immunotherapy response.•The model achieved promising performance…”
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Radiomics signature based on computed tomography images for the preoperative prediction of lymph node metastasis at individual stations in gastric cancer: A multicenter study
Published in Radiotherapy and oncology (01-12-2021)“…•Preoperative individualized lymph node metastasis prediction can guide surgical treatment for gastric cancer.•Radiomics using CT images can effectively…”
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A novel method to detect carotid artery in-stent restenosis
Published in Journal of neuroimaging (01-11-2024)“…Carotid artery stenosis is a major risk factor for ischemic stroke. Despite carotid artery stenting, in-stent restenosis (ISR) remains challenging. Pigs serve…”
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Predicting peritoneal recurrence and disease-free survival from CT images in gastric cancer with multitask deep learning: a retrospective study
Published in The Lancet. Digital health (01-05-2022)“…Peritoneal recurrence is the predominant pattern of relapse after curative-intent surgery for gastric cancer and portends a dismal prognosis. Accurate…”
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Noninvasive Prediction of Occult Peritoneal Metastasis in Gastric Cancer Using Deep Learning
Published in JAMA network open (04-01-2021)“…Occult peritoneal metastasis frequently occurs in patients with advanced gastric cancer and is poorly diagnosed with currently available tools. Because the…”
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Comprehensive assessment of immune context and immunotherapy response via noninvasive imaging in gastric cancer
Published in The Journal of clinical investigation (15-03-2024)“…The tumor immune microenvironment can provide prognostic and therapeutic information. We aimed to develop noninvasive imaging biomarkers from computed…”
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Comprehensive assessment of immune context and immunotherapy response via noninvasive imaging in gastric cancer
Published in The Journal of clinical investigation (15-03-2024)“…BACKGROUND. The tumor immune microenvironment can provide prognostic and therapeutic information. We aimed to develop noninvasive imaging biomarkers from…”
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Noninvasive imaging evaluation of peritoneal recurrence and chemotherapy benefit in gastric cancer after gastrectomy: a multicenter study
Published in International journal of surgery (London, England) (01-07-2023)“…Peritoneal recurrence (PR) is the predominant pattern of relapse after curative-intent surgery in gastric cancer (GC) and indicates a dismal prognosis…”
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