Search Results - "Chen, Chin‐Tu"

Spatial feature fusion convolutional network for liver and liver tumor segmentation from CT images by Liu, Tianyu, Liu, Junchi, Ma, Yan, He, Jiangping, Han, Jincang, Ding, Xiaoyang, Chen, Chin‐Tu

“…Purpose The accurate segmentation of liver and liver tumors from CT images can assist radiologists in decision‐making and treatment planning. The contours of…”
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Lung cancer—a fractal viewpoint by Lennon, Frances E., Cianci, Gianguido C., Cipriani, Nicole A., Hensing, Thomas A., Zhang, Hannah J., Chen, Chin-Tu, Murgu, Septimiu D., Vokes, Everett E., Vannier, Michael W., Salgia, Ravi

“…Key Points Cancer-related structural alterations in lung tissue and individual cells can often be readily observed, but can be difficult to quantify using…”
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A simplified protocol for the automated production of 2‐[18F]fluoro‐3‐[2‐((S)‐3‐pyrrolinyl)methoxy]pyridine ([18F]nifene) on an IBA Synthera® module by Bhuiyan, Mohammed, Souris, Jeffrey, Kucharski, Anna, Freifelder, Richard, Mukherjee, Jogeshwar, Chen, Chin‐Tu

“…The α4β2 nicotinic acetylcholine receptor (nAChR) ligand 2‐[18F]fluoro‐3‐[2‐((S)‐3‐pyrrolinyl)methoxy]pyridine ([18F]nifene) has been synthesized in 10%…”
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In Vivo Imaging of the Tumor‐Associated Enzyme NCEH1 with a Covalent PET Probe by Chang, Jae Won, Bhuiyan, Mohammed, Tsai, Hsiu‐Ming, Zhang, Hannah J., Li, Gang, Fathi, Shaghayegh, McCutcheon, David C., Leoni, Lara, Freifelder, Richard, Chen, Chin‐Tu, Moellering, Raymond E.

“…Herein, we report the development of an 18F‐labeled, activity‐based small‐molecule probe targeting the cancer‐associated serine hydrolase NCEH1. We undertook a…”
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Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging by Broder, Brittany A, Bhuiyan, Mohammed, Freifelder, Richard, Rotsch, David A, Chitneni, Satish K, Makinen, Marvin W, Chen, Chin-Tu

“…(acetylacetonato)oxidovanadium(IV) [(VO(acac) ], generally known as vanadyl acetylacetonate, has been shown to be preferentially sequestered in malignant…”
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Near‐Infrared Mesoporous Silica Nanoparticles for Optical Imaging: Characterization and In Vivo Biodistribution by Lee, Chia‐Hung, Cheng, Shih‐Hsun, Wang, Yu‐Jing, Chen, Yu‐Ching, Chen, Nai‐Tzu, Souris, Jeffrey, Chen, Chin‐Tu, Mou, Chung‐Yuan, Yang, Chung‐Shi, Lo, Leu‐Wei

“…The characterization of near‐infrared (NIR) mesoporous silica nanoparticles (MSN) suitable for in vivo optical imaging with high efficiency is presented…”
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Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles by Souris, Jeffrey S, Lee, Chia-Hung, Cheng, Shih-Hsun, Chen, Chin-Tu, Yang, Chung-Shi, Ho, Ja-an A, Mou, Chung-Yuan, Lo, Leu-Wei

“…Abstract Nanoparticle-assisted drug delivery has been emerging as an active research area in recent years. The in vivo biodistribution of nanoparticle and its…”
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Evaluation of an Image-Derived Input Function for Kinetic Modeling of Nicotinic Acetylcholine Receptor-Binding PET Ligands in Mice by Zammit, Matthew, Kao, Chien-Min, Zhang, Hannah J, Tsai, Hsiu-Ming, Holderman, Nathanial, Mitchell, Samuel, Tanios, Eve, Bhuiyan, Mohammed, Freifelder, Richard, Kucharski, Anna, Green, William N, Mukherjee, Jogeshwar, Chen, Chin-Tu

“…Positron emission tomography (PET) radioligands that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allow for in vivo investigations of the…”
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Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics by Meier, Jason P, Zhang, Hannah J, Freifelder, Richard, Bhuiyan, Mohammed, Selman, Phillip, Mendez, Megan, Kankanamalage, Pavithra H. A, Brossard, Thomas, Pusateri, Antonino, Tsai, Hsiu-Ming, Leoni, Lara, Penano, Sagada, Ghosh, Kaustab, Broder, Brittany A, Markiewicz, Erica, Renne, Amy, Stadler, Walter, Weichselbaum, Ralph, Nolen, Jerry, Kao, Chien-Min, Chitneni, Satish K, Rotsch, David A, Szmulewitz, Russell Z, Chen, Chin-Tu

“…In the field of nuclear medicine, the β+ -emitting 43Sc and β− -emitting 47Sc are promising candidates in cancer diagnosis and targeted radionuclide therapy…”
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Rational design of silicon structures for optically controlled multiscale biointerfaces by Jiang, Yuanwen, Li, Xiaojian, Liu, Bing, Yi, Jaeseok, Fang, Yin, Shi, Fengyuan, Gao, Xiang, Sudzilovsky, Edward, Parameswaran, Ramya, Koehler, Kelliann, Nair, Vishnu, Yue, Jiping, Guo, KuangHua, Fang, Yin, Tsai, Hsiu-Ming, Freyermuth, George, Wong, Raymond C. S., Kao, Chien-Min, Chen, Chin-Tu, Nicholls, Alan W., Wu, Xiaoyang, Shepherd, Gordon M. G., Tian, Bozhi

“…Silicon-based materials have been widely used in biological applications. However, remotely controlled and interconnect-free silicon configurations have been…”
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Nanoparticle-Programmed Self-Destructive Neural Stem Cells for Glioblastoma Targeting and Therapy by Cheng, Yu, Morshed, Ramin, Cheng, Shih-Hsun, Tobias, Alex, Auffinger, Brenda, Wainwright, Derek A., Zhang, Lingjiao, Yunis, Catherine, Han, Yu, Chen, Chin-Tu, Lo, Leu-Wei, Aboody, Karen S., Ahmed, Atique U., Lesniak, Maciej S.

“…A 3‐step glioblastoma‐tropic delivery and therapy method using nanoparticle programmed self‐destructive neural stem cells (NSCs) is demonstrated in vivo: 1)…”
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Dynamic effect of three locking plates fixated to humeral fracture based on multibody musculoskeletal model by Peng, Matthew, Chen, Chin‐Tu, MA, LiMin, JU, Xiangyang, Khambay, Balvinder

“…Objective This study attempts to analyse the biomechanical effect of internal fixation (plated in parallel or plated vertically) on the basis of distal humeral…”
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Development of a PET radioligand for potassium channels to image CNS demyelination by Brugarolas, Pedro, Sánchez-Rodríguez, Jorge E., Tsai, Hsiu-Ming, Basuli, Falguni, Cheng, Shih-Hsun, Zhang, Xiang, Caprariello, Andrew V., Lacroix, Jerome J., Freifelder, Richard, Murali, Dhanabalan, DeJesus, Onofre, Miller, Robert H., Swenson, Rolf E., Chen, Chin-Tu, Herscovitch, Peter, Reich, Daniel S., Bezanilla, Francisco, Popko, Brian

“…Central nervous system (CNS) demyelination represents the pathological hallmark of multiple sclerosis (MS) and contributes to other neurological conditions…”
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Annealing-modulated nanoscintillators for nonconventional X-ray activation of comprehensive photodynamic effects in deep cancer theranostics by Chuang, Yao-Chen, Chu, Chia-Hui, Cheng, Shih-Hsun, Liao, Lun-De, Chu, Tsung-Sheng, Chen, Nai-Tzu, Paldino, Arthur, Hsia, Yu, Chen, Chin-Tu, Lo, Leu-Wei

“…Photodynamic therapy (PDT), which involves the generation of reactive oxygen species (ROS) through interactions of a photosensitizer (PS) with light and…”
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Multiplexing Readout for Time-of-Flight (TOF) PET Detectors Using Striplines by Kim, Heejong, Kao, Chien-Min, Hua, Yuexuan, Xie, Qingguo, Chen, Chin-Tu

“…A recent trend in PET instrumentation is the use of silicon photomultipliers (SiPMs) for high resolution and time-of-flight (TOF) detection. Due to its small…”
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X-ray Activated Nanoplatforms for Deep Tissue Photodynamic Therapy by Souris, Jeffrey S, Leoni, Lara, Zhang, Hannah J, Pan, Ariel, Tanios, Eve, Tsai, Hsiu-Ming, Balyasnikova, Irina V, Bissonnette, Marc, Chen, Chin-Tu

“…Photodynamic therapy (PDT), the use of light to excite photosensitive molecules whose electronic relaxation drives the production of highly cytotoxic reactive…”
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A Preclinical Positron Emission Tomography (PET) and Electron Paramagnetic Resonance Imaging (EPRI) Hybrid System: PET Detector Module by Kim, Heejong, Hua, Yuexuan, Epel, Boris, Sundramoorthy, Subramanian, Halpern, Howard, Chen, Chin-Tu, Kao, Chien-Min

“…We report the design and experimental validation of a compact positron emission tomography (PET) detector module (DM) intended for building a preclinical PET…”
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Illuminating and Radiosensitizing Tumors with 2DG-Bound Gold-Based Nanomedicine for Targeted CT Imaging and Therapy by Sivasubramanian, Maharajan, Chu, Chia-Hui, Hsia, Yu, Chen, Nai-Tzu, Cai, Meng-Ting, Tew, Lih Shin, Chuang, Yao-Chen, Chen, Chin-Tu, Aydogan, Bulent, Liao, Lun-De, Lo, Leu-Wei

“…Although radiotherapy is one of the most important curative treatments for cancer, its clinical application is associated with undesired therapeutic effects on…”
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Aerosolized In Vivo 3D Localization of Nose-to-Brain Nanocarrier Delivery Using Multimodality Neuroimaging in a Rat Model-Protocol Development by Veronesi, Michael C, Graner, Brian D, Cheng, Shih-Hsun, Zamora, Marta, Zarrinmayeh, Hamideh, Chen, Chin-Tu, Das, Sudip K, Vannier, Michael W

“…The fate of intranasal aerosolized radiolabeled polymeric micellar nanoparticles (LPNPs) was tracked with positron emission tomography/computer tomography…”
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Sensitivity evaluation and selective plane imaging geometry for x‐ray‐induced luminescence imaging by Quigley, Bryan P., Smith, Corey D., Cheng, Shih‐Hsun, Souris, Jeffrey S., Pelizzari, Charles A., Chen, Chin‐Tu, Lo, Leu‐Wei, Reft, Chester S., Wiersma, Rodney D., La Riviere, Patrick J.

“…Purpose X‐ray‐induced luminescence (XIL) is a hybrid x‐ray/optical imaging modality that employs nanophosphors that luminescence in response to x‐ray…”
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