Search Results - "Chen, Caifu"

Characterization of microRNA expression profiles in normal human tissues by Liang, Yu, Ridzon, Dana, Wong, Linda, Chen, Caifu

“…Measuring the quantity of miRNAs in tissues of different physiological and pathological conditions is an important first step to investigate the functions of…”
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Comparison of TaqMan, KASP and rhAmp SNP genotyping platforms in hexaploid wheat by Ayalew, Habtamu, Tsang, Pak Wah, Chu, Chenggen, Wang, Junzhou, Liu, Shuyu, Chen, Caifu, Ma, Xue-Feng

“…Advances in high-throughput genotyping enable the generation of genome-scale data much more easily and at lower cost than ever before. However, small-scale and…”
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Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study by Mestdagh, Pieter, Hartmann, Nicole, Baeriswyl, Lukas, Andreasen, Ditte, Bernard, Nathalie, Chen, Caifu, Cheo, David, D'Andrade, Petula, DeMayo, Mike, Dennis, Lucas, Derveaux, Stefaan, Feng, Yun, Fulmer-Smentek, Stephanie, Gerstmayer, Bernhard, Gouffon, Julia, Grimley, Chris, Lader, Eric, Lee, Kathy Y, Luo, Shujun, Mouritzen, Peter, Narayanan, Aishwarya, Patel, Sunali, Peiffer, Sabine, Rüberg, Silvia, Schroth, Gary, Schuster, Dave, Shaffer, Jonathan M, Shelton, Elliot J, Silveria, Scott, Ulmanella, Umberto, Veeramachaneni, Vamsi, Staedtler, Frank, Peters, Thomas, Guettouche, Toumy, Wong, Linda, Vandesompele, Jo

“…12 microRNA expression profiling platforms are compared for their reproducibility, sensitivity, accuracy and specificity, and the strengths and weaknesses of…”
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High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA by Mestdagh, Pieter, Feys, Tom, Bernard, Nathalie, Guenther, Simone, Chen, Caifu, Speleman, Frank, Vandesompele, Jo

“…MicroRNAs (miRNAs) are an emerging class of small non-coding RNAs implicated in a wide variety of cellular processes. Research in this field is accelerating,…”
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Characterization of MicroRNA expression levels and their biological correlates in human cancer cell lines by GAUR, Arti, JEWELL, David A, YU LIANG, RIDZON, Dana, MOORE, Jason H, CAIFU CHEN, AMBROS, Victor R, ISRAEL, Mark A

“…MicroRNAs are small noncoding RNAs that function by regulating target gene expression posttranscriptionally. They play a critical role in developmental and…”
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A microRNA component of the p53 tumour suppressor network by Cleary, Michele A, Hannon, Gregory J, He, Lin, He, Xingyue, Lim, Lee P, de Stanchina, Elisa, Xuan, Zhenyu, Liang, Yu, Xue, Wen, Zender, Lars, Magnus, Jill, Ridzon, Dana, Jackson, Aimee L, Linsley, Peter S, Chen, Caifu, Lowe, Scott W

“…A global decrease in microRNA (miRNA) levels is often observed in human cancers, indicating that small RNAs may have an intrinsic function in tumour…”
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Quantitation of microRNAs by real-time RT-qPCR by Chen, Caifu, Tan, Ruoying, Wong, Linda, Fekete, Richard, Halsey, Jason

“…MicroRNAs (miRNAs) are ∼22 nucleotide regulatory RNA molecules that play important roles in controlling developmental and physiological processes in animals…”
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A Genome-wide RNAi Screen Draws a Genetic Framework for Transposon Control and Primary piRNA Biogenesis in Drosophila by Muerdter, Felix, Guzzardo, Paloma M., Gillis, Jesse, Luo, Yicheng, Yu, Yang, Chen, Caifu, Fekete, Richard, Hannon, Gregory J.

“…A large fraction of our genome consists of mobile genetic elements. Governing transposons in germ cells is critically important, and failure to do so…”
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A lncRNA fine tunes the dynamics of a cell state transition involving Lin28 , let-7 and de novo DNA methylation by Li, Meng Amy, Amaral, Paulo P, Cheung, Priscilla, Bergmann, Jan H, Kinoshita, Masaki, Kalkan, Tüzer, Ralser, Meryem, Robson, Sam, von Meyenn, Ferdinand, Paramor, Maike, Yang, Fengtang, Chen, Caifu, Nichols, Jennifer, Spector, David L, Kouzarides, Tony, He, Lin, Smith, Austin

“…Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated for lineage…”
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MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia by SCHOTTE, Diana, DE MENEZES, Renée X, AKBARI MOQADAM, Farhad, MOHAMMADI KHANKAHDANI, Leila, LANGE-TURENHOUT, Ellen, CHEN, Caifu, PIETERS, Rob, DEN BOER, Monique L

“…MicroRNA regulate the activity of protein-coding genes including those involved in hematopoietic cancers. The aim of the current study was to explore which…”
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The microRNA body map: dissecting microRNA function through integrative genomics by Mestdagh, Pieter, Lefever, Steve, Pattyn, Filip, Ridzon, Dana, Fredlund, Erik, Fieuw, Annelies, Ongenaert, Maté, Vermeulen, Joëlle, De Paepe, Anne, Wong, Linda, Speleman, Frank, Chen, Caifu, Vandesompele, Jo

“…While a growing body of evidence implicates regulatory miRNA modules in various aspects of human disease and development, insights into specific miRNA function…”
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miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples by DE PRETER, Katleen, MESTDAGH, Pieter, HOGARTY, Michael D, IZYCKA-SWIESZEWSKA, Ewa, LONDON, Wendy B, NOGUERA, Rosa, PIQUERAS, Marta, BRYAN, Kenneth, SCHOWE, Benjamin, VAN SLUIS, Peter, MOLENAAR, Jan J, SCHRAMM, Alexander, VERMEULEN, Joëlle, SCHULTE, Johannes H, STALLINGS, Raymond L, VERSTEEG, Rogier, LAUREYS, Geneviève, VAN ROY, Nadine, SPELEMAN, Frank, VANDESOMPELE, Jo, ZEKA, Fjoralba, NARANJO, Arlene, BRAY, Isabella, CASTEL, Victoria, CAIFU CHEN, DROZYNSKA, Elzbieta, EGGERT, Angelika

“…More accurate assessment of prognosis is important to further improve the choice of risk-related therapy in neuroblastoma (NB) patients. In this study, we…”
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A genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis by Goh, Wee-Siong Sho, Seah, Jun Wen Eugene, Harrison, Emily J, Chen, Caifu, Hammell, Christopher M, Hannon, Gregory J

“…In animals, piRNAs and their associated Piwi proteins guard germ cell genomes against mobile genetic elements via an RNAi-like mechanism. In Caenorhabditis…”
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Comprehensive Evaluation and Application of a Novel Method to Isolate Cell-Free DNA Derived From Bile of Biliary Tract Cancer Patients by Shen, Ningjia, Zhu, Bin, Zhang, Wei, Nian, Baoning, Xu, Xiaoya, Yu, Lianghe, Ruan, Xiang, Chen, Sheng, Liu, Yang, Cao, Xinkai, Shi, Xintong, Li, Zhikuan, Huang, Xingfeng, Wang, Xiang, Chen, Caifu, Xiong, Lei, Zhang, Dadong, Fu, Xiaohui, Zhang, Yongjie

“…Cell-free DNA (cfDNA) exists in various types of bodily fluids, including plasma, urine, bile, and others. Bile cfDNA could serve as a promising liquid biopsy…”
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Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines by Wu, Hao, Xu, Jun, Pang, Zhiping P, Ge, Weihong, Kim, Kevin J, Blanchi, Bruno, Chen, Caifu, Südhof, Thomas C, Sun, Yi E

“…The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially…”
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MicroRNA programs in normal and aberrant stem and progenitor cells by Arnold, Christopher P, Tan, Ruoying, Zhou, Baiyu, Yue, Si-Biao, Schaffert, Steven, Biggs, Joseph R, Doyonnas, Regis, Lo, Miao-Chia, Perry, John M, Renault, Valérie M, Sacco, Alessandra, Somervaille, Tim, Viatour, Patrick, Brunet, Anne, Cleary, Michael L, Li, Linheng, Sage, Julien, Zhang, Dong-Er, Blau, Helen M, Chen, Caifu, Chen, Chang-Zheng

“…Emerging evidence suggests that microRNAs (miRNAs), an abundant class of ∼22-nucleotide small regulatory RNAs, play key roles in controlling the…”
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Multiplexing RT-PCR for the detection of multiple miRNA species in small samples by Lao, Kaiqin, Xu, Nan Lan, Yeung, Vivian, Chen, Caifu, Livak, Kenneth J., Straus, Neil A.

“…MicroRNAs are short (∼22 nucleotides), non-coding RNAs that play critical roles in gene regulation and may be used as rapid precise diagnostic indicators of…”
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Real-time PCR quantification of precursor and mature microRNA by Schmittgen, Thomas D., Lee, Eun Joo, Jiang, Jinmai, Sarkar, Anasuya, Yang, Liuqing, Elton, Terry S., Chen, Caifu

“…microRNAs (miRNAs) are challenging molecules to amplify by PCR because the miRNA precursor consists of a stable hairpin and the mature miRNA is roughly the…”
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miR-34 miRNAs provide a barrier for somatic cell reprogramming by He, Lin, Choi, Yong Jin, Lin, Chao-Po, Ho, Jaclyn J, He, Xingyue, Okada, Nobuhiro, Bu, Pengcheng, Zhong, Yingchao, Kim, Sang Yong, Bennett, Margaux J, Chen, Caifu, Ozturk, Arzu, Hicks, Geoffrey G, Hannon, Greg J

“…Somatic reprogramming induced by defined transcription factors is a low-efficiency process that is enhanced by p53 deficiency. So far, p21 is the only p53…”
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miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts by Xue, Bin, Chuang, Chen-Hua, Prosser, Haydn M, Fuziwara, Cesar Seigi, Chan, Claudia, Sahasrabudhe, Neil, Kühn, Maximilian, Wu, Yalei, Chen, Jingqi, Biton, Anne, Chen, Caifu, Wilkinson, John Erby, McManus, Michael T, Bradley, Allan, Winslow, Monte M, Su, Bo, He, Lin

“…Lung adenocarcinoma, the most prevalent lung cancer subtype, is characterized by its high propensity to metastasize. Despite the importance of metastasis in…”
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