Search Results - "Chen, Bingkun K"

Open-Spaced Ridged Hydrogel Scaffolds Containing TiO2-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M., Thiele, Frederic, Stewart, Rachel N., Rangnick, Simone, Weiss, Georgina J., Chen, Bingkun K., Silvernail, Jodi L., Strickland, Tammy, Nesbitt, Jarred J., Lim, Kelly, Schwarzbauer, Jean E., Schwartz, Jeffrey, Yaszemski, Michael J., Windebank, Anthony J., Madigan, Nicolas N.

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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Comparison of polymer scaffolds in rat spinal cord: A step toward quantitative assessment of combinatorial approaches to spinal cord repair by Chen, Bingkun K, Knight, Andrew M, Madigan, Nicolas N, Gross, LouAnn, Dadsetan, Mahrokh, Nesbitt, Jarred J, Rooney, Gemma E, Currier, Bradford L, Yaszemski, Michael J, Spinner, Robert J, Windebank, Anthony J

“…Abstract The transected rat thoracic (T9/10 ) spinal cord model is a platform for quantitatively comparing biodegradable polymer scaffolds. Schwann cell-loaded…”
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Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord by Madigan, Nicolas N, Chen, Bingkun K, Knight, Andrew M, Rooney, Gemma E, Sweeney, Eva, Kinnavane, Lisa, Yaszemski, Michael J, Dockery, Peter, O'Brien, Timothy, McMahon, Siobhan S, Windebank, Anthony J

“…The use of multichannel polymer scaffolds in a complete spinal cord transection injury serves as a deconstructed model that allows for control of individual…”
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Newly regenerated axons via scaffolds promote sub-lesional reorganization and motor recovery with epidural electrical stimulation by Siddiqui, Ahad M., Islam, Riazul, Cuellar, Carlos A., Silvernail, Jodi L., Knudsen, Bruce, Curley, Dallece E., Strickland, Tammy, Manske, Emilee, Suwan, Parita T., Latypov, Timur, Akhmetov, Nafis, Zhang, Shuya, Summer, Priska, Nesbitt, Jarred J., Chen, Bingkun K., Grahn, Peter J., Madigan, Nicolas N., Yaszemski, Michael J., Windebank, Anthony J., Lavrov, Igor A.

“…Here, we report the effect of newly regenerated axons via scaffolds on reorganization of spinal circuitry and restoration of motor functions with epidural…”
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Hemisection spinal cord injury in rat: The value of intraoperative somatosensory evoked potential monitoring by Cloud, Beth A., Ball, Bret G., Chen, Bingkun K., Knight, Andrew M., Hakim, Jeffrey S., Ortiz, Ana M., Windebank, Anthony J.

“…► Somatosensory evoked potentials to assess hemisection spinal cord injury in rats. ► Intraoperative somatosensory evoked potentials relate to post-mortem…”
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Implantation of cauda equina nerve roots through a biodegradable scaffold at the conus medullaris in rat by Grahn, Peter J., BA, Vaishya, Sandeep, MD, Knight, Andrew M., PhD, Chen, Bingkun K., MD, PhD, Schmeichel, Ann M, Currier, Bradford L., MD, Spinner, Robert J., MD, Yaszemski, Michael J., MD, PhD, Windebank, Anthony J., MD

“…Abstract Background context Traumatic injuries occurring at the conus medullaris of the spinal cord cause permanent damage both to the central nervous system…”
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The Translesional Spinal Network and Its Reorganization after Spinal Cord Injury by Krupa, Petr, Siddiqui, Ahad M., Grahn, Peter J., Islam, Riazul, Chen, Bingkun K., Madigan, Nicolas N., Windebank, Anthony J., Lavrov, Igor A.

“…Evidence from preclinical and clinical research suggest that neuromodulation technologies can facilitate the sublesional spinal networks, isolated from…”
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GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats by Chen, Bingkun K., Madigan, Nicolas N., Hakim, Jeffrey S., Dadsetan, Mahrokh, McMahon, Siobhan S., Yaszemski, Michael J., Windebank, Anthony J.

“…Positively‐charged oligo[poly(ethylene glycol)fumarate] (OPF+) is a biodegradable hydrogel used for spinal cord injury repair. We compared scaffolds containing…”
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Early and sustained improvements in motor function in rats after infusion of allogeneic umbilical cord-derived mesenchymal stem cells following spinal cord injury by Moinuddin, F. M., Yolcu, Yagiz U., Wahood, Waseem, Siddiqui, Ahad M., Chen, Bingkun K., Alvi, Mohammed Ali, Goyal, Anshit, Nesbitt, Jarred J., Windebank, Anthony J., Yeh, Jiunn-chern, Petrucci, Kathy, Bydon, Mohamad

“…Study design Animal study. Objectives Umbilical cord-derived mesenchymal stem cells (UC-MSCs) have recently been shown to hold great therapeutic potential for…”
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Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat by Hakim, Jeffrey S, Esmaeili Rad, Melika, Grahn, Peter J, Chen, Bingkun K, Knight, Andrew M, Schmeichel, Ann M, Isaq, Nasro A, Dadsetan, Mahrokh, Yaszemski, Michael J, Windebank, Anthony J

“…Positively charged oligo[poly(ethylene glycol) fumarate] (OPF+) scaffolds loaded with Schwann cells bridge spinal cord injury (SCI) lesions and support axonal…”
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Combinatorial tissue engineering partially restores function after spinal cord injury by Hakim, Jeffrey S., Rodysill, Brian R., Chen, Bingkun K., Schmeichel, Ann M., Yaszemski, Michael J., Windebank, Anthony J., Madigan, Nicolas N.

“…Hydrogel scaffolds provide a beneficial microenvironment in transected rat spinal cord. A combinatorial biomaterials‐based strategy provided a microenvironment…”
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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials by Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.

“…Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative…”
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Optimizing conditions and avoiding pitfalls for prolonged axonal tracing with carbocyanine dyes in fixed rat spinal cords by Chen, Bingkun K., Miller, Steven M., Mantilla, Carlos B., Gross, LouAnn, Yaszemski, Michael J., Windebank, Anthony J.

“…We have characterized a method of labeling of axons in the post-mortem spinal cord using a silastic disc holding pins coated with DiI and DiO at the rostral…”
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO[sub.2]-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M, Thiele, Frederic, Stewart, Rachel N, Rangnick, Simone, Weiss, Georgina J, Chen, Bingkun K, Silvernail, Jodi L, Strickland, Tammy, Nesbitt, Jarred J, Lim, Kelly, Schwarzbauer, Jean E, Schwartz, Jeffrey, Yaszemski, Michael J, Windebank, Anthony J, Madigan, Nicolas N

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
Get full text

Open-Spaced Ridged Hydrogel Scaffolds Containing TiO 2 -Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M, Thiele, Frederic, Stewart, Rachel N, Rangnick, Simone, Weiss, Georgina J, Chen, Bingkun K, Silvernail, Jodi L, Strickland, Tammy, Nesbitt, Jarred J, Lim, Kelly, Schwarzbauer, Jean E, Schwartz, Jeffrey, Yaszemski, Michael J, Windebank, Anthony J, Madigan, Nicolas N

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats: OPF+ hydrogel scaffolds for spinal cord injury repair by Chen, Bingkun K., Madigan, Nicolas N., Hakim, Jeffrey S., Dadsetan, Mahrokh, McMahon, Siobhan S., Yaszemski, Michael J., Windebank, Anthony J.

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Abstract #76: Neuromodulation of the spinal cord regeneration with epidural stimulation and Schwann cell seeded hydrogel scaffolds by Cuellar, Carlos A., Siddiqui, Ahad M., Silvernail, Jodi L., Chen, Bingkun K., Knudsen, Bruce, Nesbitt, Jarred J., Grahn, Peter J., Madigan, Nicolas N., Windebank, Anthony J., Lavrov, Igor A.

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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting P hase I human trials by Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.

“…Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative…”
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