Search Results - "Chen, Billy T."

Central role for the insular cortex in mediating conditioned responses to anticipatory cues by Kusumoto-Yoshida, Ikue, Liu, Haixin, Chen, Billy T., Fontanini, Alfredo, Bonci, Antonello

“…Significance Classical studies have been focused on understanding the role of gustatory areas in evaluating the sensory component of taste. However, recent…”
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Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake by Seif, Taban, Chang, Shao-Ju, Simms, Jeffrey A, Gibb, Stuart L, Dadgar, Jahan, Chen, Billy T, Harvey, Brandon K, Ron, Dorit, Messing, Robert O, Bonci, Antonello, Hopf, F Woodward

“…The authors show that optogenetic inhibition of inputs from medial prefrontal cortex (mPFC) or insula to the nucleus accumbens core (NAcore) inhibits…”
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Orexin A/Hypocretin-1 Selectively Promotes Motivation for Positive Reinforcers by Borgland, Stephanie L, Chang, Shao-Ju, Bowers, M. Scott, Thompson, Jennifer L, Vittoz, Nicole, Floresco, Stan B, Chou, Jonathan, Chen, Billy T, Bonci, Antonello

“…Orexin A/hypocretin-1 (oxA/hcrt-1) is known to be a modulator of dopamine-dependent neuronal activity and behaviors. However, the role of this system in…”
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AMPA Receptor Synaptic Plasticity Induced by Psychostimulants: The Past, Present, and Therapeutic Future by Bowers, M. Scott, Chen, Billy T., Bonci, Antonello

“…Experience-dependent plasticity at excitatory synapses of the mesocorticolimbic system is a fundamental brain mechanism that enables adaptation to an…”
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Cocaine self-administration selectively abolishes LTD in the core of the nucleus accumbens by Bonci, Antonello, Martin, Miquel, Chen, Billy T, Hopf, F Woodward, Bowers, M Scott

“…The core and shell of the nucleus accumbens have critical, differential roles in drug-dependent behaviors. Here we show that operant cocaine…”
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Pontomesencephalic Tegmental Afferents to VTA Non-dopamine Neurons Are Necessary for Appetitive Pavlovian Learning by Yau, Hau-Jie, Wang, Dong V., Tsou, Jen-Hui, Chuang, Yi-Fang, Chen, Billy T., Deisseroth, Karl, Ikemoto, Satoshi, Bonci, Antonello

“…The ventral tegmental area (VTA) receives phenotypically distinct innervations from the pedunculopontine tegmental nucleus (PPTg). While PPTg-to-VTA inputs are…”
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Dorsal medial prefrontal cortex (MPFC) circuitry in rodent models of cocaine use: implications for drug addiction therapies by Jasinska, Agnes J., Chen, Billy T., Bonci, Antonello, Stein, Elliot A.

“…Although the importance of the medial prefrontal cortex (MPFC) in cocaine addiction is well established, its precise contribution to cocaine seeking, taking…”
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Withdrawal From Intermittent Ethanol Exposure Increases Probability of Burst Firing in VTA Neurons In Vitro by Hopf, F. Woodward, Martin, Miquel, Chen, Billy T, Bowers, M. Scott, Mohamedi, Maysha M, Bonci, Antonello

“…Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, California Submitted 24 July 2007;…”
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Endogenous Hydrogen Peroxide Regulates the Excitability of Midbrain Dopamine Neurons via ATP-Sensitive Potassium Channels by Avshalumov, Marat V, Chen, Billy T, Koos, Tibor, Tepper, James M, Rice, Margaret E

“…ATP-sensitive K+ (K(ATP)) channels link metabolic state to cell excitability. Here, we examined regulation of K(ATP) channels in substantia nigra dopamine…”
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Neuroplastic alterations in the limbic system following cocaine or alcohol exposure by Stuber, Garret D, Hopf, F Woodward, Tye, Kay M, Chen, Billy T, Bonci, Antonello

“…Neuroplastic changes in the CNS are thought to be a fundamental component of learning and memory. While pioneering studies in the hippocampus and cerebellum…”
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Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking by Chen, Billy T., Yau, Hau-Jie, Hatch, Christina, Kusumoto-Yoshida, Ikue, Cho, Saemi L., Hopf, F. Woodward, Bonci, Antonello

“…A study of compulsive drug-seeking behaviour in rats reveals that prolonged cocaine self-administration decreases prelimbic cortex activity resulting in…”
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H2O2 Is a Novel, Endogenous Modulator of Synaptic Dopamine Release by Chen, Billy T, Avshalumov, Marat V, Rice, Margaret E

“…Departments of Physiology and Neuroscience and Neurosurgery, New York University School of Medicine, New York, New York 10016 Chen, Billy T., Marat V…”
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Differential calcium dependence of axonal versus somatodendritic dopamine release, with characteristics of both in the ventral tegmental area by Chen, Billy T, Patel, Jyoti C, Moran, Kimberly A, Rice, Margaret E

“…Midbrain dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) exhibit somatodendritic release of DA. Previous…”
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Synaptic plasticity in the mesolimbic system: therapeutic implications for substance abuse by Chen, Billy T, Hopf, F Woodward, Bonci, Antonello

“…In an ever-changing environment, animals must learn new behavioral strategies for the successful procurement of food, sex, and other needs. Synaptic plasticity…”
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Cocaine but Not Natural Reward Self-Administration nor Passive Cocaine Infusion Produces Persistent LTP in the VTA by Chen, Billy T., Bowers, M. Scott, Martin, Miquel, Hopf, F. Woodward, Guillory, Anitra M., Carelli, Regina M., Chou, Jonathan K., Bonci, Antonello

“…Persistent drug-seeking behavior is hypothesized to co-opt the brain's natural reward-motivational system. Although ventral tegmental area (VTA) dopamine (DA)…”
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Synaptic regulation of somatodendritic dopamine release by glutamate and GABA differs between substantia nigra and ventral tegmental area by Chen, Billy T., Rice, Margaret E.

“…Midbrain dopamine (DA) cells of the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA) exhibit somatodendritic release of DA. To address…”
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Reduced Nucleus Accumbens SK Channel Activity Enhances Alcohol Seeking during Abstinence by Hopf, F. Woodward, Bowers, M. Scott, Chang, Shao-Ju, Chen, Billy T., Martin, Miguel, Seif, Taban, Cho, Saemi L., Tye, Kay, Bonci, Antonello

“…The cellular mechanisms underlying pathological alcohol seeking remain poorly understood. Here, we show an enhancement of nucleus accumbens (NAcb) core action…”
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The small-conductance calcium-activated potassium channel is a key modulator of firing and long-term depression in the dorsal striatum by Woodward Hopf, F., Seif, Taban, Mohamedi, Maysha L., Chen, Billy T., Bonci, Antonello

“…The striatum is considered to be critical for the control of goal‐directed action, with the lateral dorsal striatum (latDS) being implicated in modulation of…”
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Limited regulation of somatodendritic dopamine release by voltage-sensitive Ca channels contrasted with strong regulation of axonal dopamine release by Chen, Billy T, Moran, Kimberly A, Avshalumov, Marat V, Rice, Margaret E

“…The mechanism underlying somatodendritic release of dopamine (DA) appears to differ from that of axon-terminal release. Specifically, somatodendritic DA…”
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Glutamate-Dependent Inhibition of Dopamine Release in Striatum Is Mediated by a New Diffusible Messenger, H2O2 by Avshalumov, Marat V, Chen, Billy T, Marshall, Sarah P, Pena, Dianna M, Rice, Margaret E

“…How glutamate regulates dopamine (DA) release in striatum has been a controversial issue. Here, we resolve this by showing that glutamate, acting at AMPA…”
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