Search Results - "Chen, Bao Nan"

Sympathetic Pathways Target Cholinergic Neurons in the Human Colonic Myenteric Plexus by Parker, Dominic R, Wiklendt, Lukasz, Humenick, Adam, Chen, Bao Nan, Sia, Tiong Cheng, Wattchow, David A, Dinning, Phil G, Brookes, Simon J H

“…The sympathetic nervous system inhibits human colonic motility largely by effects on enteric neurons. Noradrenergic axons, which branch extensively in the…”
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Characterization of viscerofugal neurons in human colon by retrograde tracing and multi-layer immunohistochemistry by Chen, Bao Nan, Humenick, Adam G, Hibberd, Timothy James, Yew, Wai Ping, Wattchow, David A, Dinning, Phil G, Costa, Marcello, Spencer, Nick J, Brookes, Simon J H

“…Viscerofugal neurons (VFNs) have cell bodies in the myenteric plexus and axons that project to sympathetic prevertebral ganglia. In animals they activate…”
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Characterization of projections of longitudinal muscle motor neurons in human colon by Humenick, Adam, Chen, Bao Nan, Lauder, Chris I. W., Wattchow, David A., Zagorodnyuk, Vladimir P., Dinning, Phil G., Spencer, Nick J., Costa, Marcello, Brookes, Simon J. H.

“…Background The enteric nervous system contains inhibitory and excitatory motor neurons which modulate smooth muscle contractility. Cell bodies of longitudinal…”
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4‐aminopyridine‐ and dendrotoxin‐sensitive potassium channels influence excitability of vagal mechano‐sensitive endings in guinea‐pig oesophagus by Zagorodnyuk, Vladimir P, Chen, Bao Nan, Costa, Marcello, Brookes, Simon J H

“…Distension‐sensitive vagal afferent fibres from the guinea‐pig oesophagus were recorded extracellularly in vitro. Most recorded units were spontaneously active…”
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Intraganglionic laminar endings are mechano-transduction sites of vagal tension receptors in the guinea-pig stomach by Zagorodnyuk, Vladimir P., Chen, Bao Nan, Brookes, Simon J. H.

“…Distension-sensitive vagal afferent fibres from the cardiac region of the guinea-pig stomach were recorded extracellularly, then filled with biotinamide, using…”
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Mechanotransduction by intraganglionic laminar endings of vagal tension receptors in the guinea-pig oesophagus by Zagorodnyuk, Vladimir P., Chen, Bao Nan, Costa, Marcello, Brookes, Simon J. H.

“…Vagal mechanoreceptors to the guinea-pig oesophagus, recorded extracellularly, in vitro , fired spontaneously at 3.3 ± 0.2 Hz, ( n = 75, from 57 animals), and…”
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Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity by Xie, Zili, Feng, Jing, Hibberd, Timothy J., Chen, Bao Nan, Zhao, Yonghui, Zang, Kaikai, Hu, Xueming, Yang, Xingliang, Chen, Lvyi, Brookes, Simon J., Spencer, Nick J., Hu, Hongzhen

“…Inflammatory and functional gastrointestinal disorders such as irritable bowel syndrome (IBS) and obstructive bowel disorder (OBD) underlie the most prevalent…”
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Multiplexed Immunohistochemistry to Identify Systematically Classes of Human Colonic Myenteric Neurons by Brookes, Simon Jonathan, Humenick, Adam, Chen, Bao Nan, Dinning, Phil G, Costa, Marcello, Wattchow, David

“…Abstract only Objective The enteric nervous system (ENS) comprises multiple classes of nerve cells which can be distinguished by combinations of…”
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Electrophysiological and morphological features of myenteric neurons of human colon revealed by intracellular recording and dye fills by Yew, Wai Ping, Humenick, Adam, Chen, Bao Nan, Wattchow, David A., Costa, Marcello, Dinning, Phil G., Brookes, Simon J. H.

“…Background Ex vivo intracellular recordings and dye fills, combined with immunohistochemistry, are a powerful way to analyze the enteric nervous system of…”
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Characterization of putative interneurons in the myenteric plexus of human colon by Humenick, Adam, Chen, Bao Nan, Wattchow, David A., Zagorodnyuk, Vladimir P., Dinning, Phil G., Spencer, Nick J., Costa, Marcello, Brookes, Simon J. H.

“…Background The enteric nervous system contains multiple classes of neurons, distinguishable by morphology, immunohistochemical markers, and projections;…”
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CGRPα within the Trpv1-Cre population contributes to visceral nociception by Spencer, Nick J, Magnúsdóttir, Elín I, Jakobsson, Jon E T, Kestell, Garreth, Chen, Bao Nan, Morris, David, Brookes, Simon J, Lagerström, Malin C

“…The role of calcitonin gene-related peptide (CGRP) in visceral and somatic nociception is incompletely understood. CGRPα is highly expressed in sensory neurons…”
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Types of Neurons in the Human Colonic Myenteric Plexus Identified by Multilayer Immunohistochemical CodingSummary by Bao Nan Chen, Adam Humenick, Wai Ping Yew, Rochelle A. Peterson, Lukasz Wiklendt, Phil G. Dinning, Nick J. Spencer, David A. Wattchow, Marcello Costa, Simon J.H. Brookes

“…Background and Aims: Gut functions including motility, secretion, and blood flow are largely controlled by the enteric nervous system. Characterizing the…”
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Loss of visceral pain following colorectal distension in an endothelin‐3 deficient mouse model of Hirschsprung's disease by Zagorodnyuk, Vladimir P., Kyloh, Melinda, Nicholas, Sarah, Peiris, Heshan, Brookes, Simon J., Chen, Bao Nan, Spencer, Nick J.

“…Non‐technical summary  The endothelin‐3 (ET‐3) gene is essential for the development of the enteric nervous system in the gastrointestinal tract of mammals,…”
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Neurochemical characterization of extrinsic nerves in myenteric ganglia of the guinea pig distal colon by Chen, Bao Nan, Sharrad, Dale F., Hibberd, Timothy J., Zagorodnyuk, Vladimir P., Costa, Marcello, Brookes, Simon J.H.

“…ABSTRACT Extrinsic nerves to the gut influence the absorption of water and electrolytes and expulsion of waste contents, largely via regulation of enteric…”
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Types of Neurons in the Human Colonic Myenteric Plexus Identified by Multilayer Immunohistochemical Coding by Chen, Bao Nan, Humenick, Adam, Yew, Wai Ping, Peterson, Rochelle A., Wiklendt, Lukasz, Dinning, Phil G., Spencer, Nick J., Wattchow, David A., Costa, Marcello, Brookes, Simon J.H.

“…Gut functions including motility, secretion, and blood flow are largely controlled by the enteric nervous system. Characterizing the different classes of…”
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Identification of Medium/High-Threshold Extrinsic Mechanosensitive Afferent Nerves to the Gastrointestinal Tract by Song, Xingyun, Chen, Bao Nan, Zagorodnyuk, Vladimir P, Lynn, Penny A, Blackshaw, L. Ashley, Grundy, David, Brunsden, Alan M, Costa, Marcello, Brookes, Simon J.H

“…Background & Aims Large distentions reliably evoke sensation from the noninflamed, nonischemic bowel, but the specialized afferent axonal structures…”
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Neurochemical coding compared between varicose axons and cell bodies of myenteric neurons in the guinea-pig ileum by Sharrad, Dale F., Chen, Bao Nan, Brookes, Simon J.H.

“…► Combinations of immunohistochemical markers are used to classify enteric neurons. ► Here, markers in cell bodies were compared with varicose axonal…”
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Tu1880 What Do Extrinsic Sensory Neurons “Tell” the Body About Gut Motility? by Chen, Bao-Nan, Humenick, Adam, Wiklendt, Lukasz, Spencer, Nicholas J, Dinning, Philip G, Costa, Marcello, Brookes, Simon J

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Tu1879 Mechanosensitivity of Spinal Sensory Axons on Mesenteric Blood Vessels in the Guinea Pig Small Intestine by Humenick, Adam, Chen, Bao-Nan, Wiklendt, Lukasz, Dinning, Philip G, Spencer, Nicholas J, Costa, Marcello, Brookes, Simon J

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Sensory innervation of the guinea pig colon and rectum compared using retrograde tracing and immunohistochemistry by Chen, B. N., Olsson, C., Sharrad, D. F., Brookes, S. J. H.

“…Background Neurons in lumbar and sacral dorsal root ganglia (DRG) comprise extrinsic sensory pathways to the distal colon and rectum, but their relative…”
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