Search Results - "Chemico-biological interactions"

Essential metals in health and disease by Jomova, Klaudia, Makova, Marianna, Alomar, Suliman Y., Alwasel, Saleh H., Nepovimova, Eugenie, Kuca, Kamil, Rhodes, Christopher J., Valko, Marian

“…In total, twenty elements appear to be essential for the correct functioning of the human body, half of which are metals and half are non-metals. Among those…”
Get full text

New insights into TGF-β/Smad signaling in tissue fibrosis by Hu, He-He, Chen, Dan-Qian, Wang, Yan-Ni, Feng, Ya-Long, Cao, Gang, Vaziri, Nosratola D., Zhao, Ying-Yong

“…Transforming growth factor-β1 (TGF-β1) is considered as a crucial mediator in tissue fibrosis and causes tissue scarring largely by activating its downstream…”
Get full text

Roles of flavonoids against coronavirus infection by Russo, Maria, Moccia, Stefania, Spagnuolo, Carmela, Tedesco, Idolo, Russo, Gian Luigi

“…In terms of public health, the 21st century has been characterized by coronavirus pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV…”
Get full text

Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases by Mehta, Meenu, Deeksha, Tewari, Devesh, Gupta, Gaurav, Awasthi, Rajendra, Singh, Harjeet, Pandey, Parijat, Chellappan, Dinesh Kumar, Wadhwa, Ridhima, Collet, Trudi, Hansbro, Philip M., Kumar, S Rajesh, Thangavelu, Lakshmi, Negi, Poonam, Dua, Kamal, Satija, Saurabh

“…Oligonucleotide-based therapies are advanced novel interventions used in the management of various respiratory diseases such as asthma and Chronic Obstructive…”
Get full text

Nuclear factor-kappa B and its role in inflammatory lung disease by Alharbi, Khalid Saad, Fuloria, Neeraj Kumar, Fuloria, Shivkanya, Rahman, Sk Batin, Al-Malki, Waleed Hassan, Javed Shaikh, Mohammad Arshad, Thangavelu, Lakshmi, Singh, Sachin K., Rama Raju Allam, Venkata Sita, Jha, Niraj Kumar, Chellappan, Dinesh Kumar, Dua, Kamal, Gupta, Gaurav

“…Nuclear factor-kappa B, involved in inflammation, host immune response, cell adhesion, growth signals, cell proliferation, cell differentiation, and apoptosis…”
Get full text

Synergistic interactions of phytochemicals with antimicrobial agents: Potential strategy to counteract drug resistance by Ayaz, Muhammad, Ullah, Farhat, Sadiq, Abdul, Ullah, Farman, Ovais, Muhammad, Ahmed, Jawad, Devkota, Hari Prasad

“…The emergence of multidrug resistant (MDR) pathogens is a global threat and has created problems in providing adequate treatment of many infectious diseases…”
Get full text

Free radicals, reactive oxygen species, oxidative stress and its classification by Lushchak, Volodymyr I.

“…[Display omitted] •Generation and elimination of reactive oxygen species (ROS) are balanced under normal conditions.•ROS homeostasis disturbances may be…”
Get full text

Mechanism and regulation of pyroptosis-mediated in cancer cell death by Ruan, Jianwei, Wang, Shijian, Wang, Jiabing

“…Pyroptosis, a form of programmed cell death, has garnered increasing attention as it relates to innate immunity and diseases. The discovery of…”
Get full text

Mechanistic study on antibacterial action of zinc oxide nanoparticles synthesized using green route by Happy Agarwal, Soumya Menon, Venkat Kumar, S., Rajeshkumar, S.

“…A large array of diseases caused by bacterial pathogens and origination of multidrug resistance in their gene provokes the need of developing new vectors or…”
Get full text

High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms by Lian, Cai-Yu, Zhai, Zhen-Zhen, Li, Zi-Fa, Wang, Lin

“…Obesity is characterized by the deposition of excessive body fat, and is caused by energy imbalance, especially when consuming fat-rich diets. High fat diet…”
Get full text

Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications by Khan, Zidan, Nath, Nikhil, Rauf, Abdur, Emran, Talha Bin, Mitra, Saikat, Islam, Fahadul, Chandran, Deepak, Barua, Jackie, Khandaker, Mayeen Uddin, Idris, Abubakr M., Wilairatana, Polrat, Thiruvengadam, Muthu

“…Currently, available therapeutic medications are both costly as well as not entirely promising in terms of potency. So, new candidates from natural resources…”
Get full text

Mechanism of plant-mediated synthesis of silver nanoparticles – A review on biomolecules involved, characterisation and antibacterial activity by Rajeshkumar, S., Bharath, L.V.

“…Engineering a reliable and eco-accommodating methodology for the synthesis of metal nanoparticles is a crucial step in the field of nanotechnology…”
Get full text

Hesperetin relieves cisplatin-induced acute kidney injury by mitigating oxidative stress, inflammation and apoptosis by Chen, Xinliang, Wei, Wei, Li, Yazhen, Huang, Jingbo, Ci, Xinxin

“…Although cisplatin is an effective anticancer drug, its clinical application is limited due to various side effects, especially nephrotoxicity. In this study,…”
Get full text

Multidrug resistant tuberculosis – Diagnostic challenges and its conquering by nanotechnology approach – An overview by Muthukrishnan, Lakshmipathy

“…One of the leading killer diseases that target the parenchymal tissues of lungs is Tuberculosis. Although antimycobacterial drugs are available, there are…”
Get full text

Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties by Zhang, Xumin, Xie, Long, Long, Jiaying, Xie, Qingxuan, Zheng, Yu, Liu, Kai, Li, Xiaofang

“…Salidroside has been identified as one of the most potent compounds isolated from various Rhodiola plants, which have been used for a long time as adaptogens…”
Get full text

Colon cancer and colorectal cancer: Prevention and treatment by potential natural products by Islam, Md Rezaul, Akash, Shopnil, Rahman, Md Mominur, Nowrin, Feana Tasmim, Akter, Tamanna, Shohag, Sheikh, Rauf, Abdur, Aljohani, Abdullah S.M., Simal-Gandara, Jesus

“…Colon cancer affects both men and women and is the world's second most significant cause of cancer-related mortality. Colon cancer death rates have risen…”
Get full text

Limonene: Aroma of innovation in health and disease by Vieira, A.J., Beserra, F.P., Souza, M.C., Totti, B.M., Rozza, A.L.

“…Natural products obtained in dietary components may aid the prevention and treatment of a variety of diseases. Reports in the scientific literature have…”
Get full text

Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis by Li, Ming, Meng, Zhaoli, Yu, Shichao, Li, Jiarui, Wang, Yupeng, Yang, Wei, Wu, Hui

“…Accumulating evidence have indicated that ferroptosis plays a crucial role in cerebral ischemia-reperfusion (I/R) injury which is the most serious treatment…”
Get full text

Toxicity of carbon-based nanomaterials: Reviewing recent reports in medical and biological systems by Madannejad, Rasoul, Shoaie, Nahid, Jahanpeyma, Fatemeh, Darvishi, Mohammad Hasan, Azimzadeh, Mostafa, Javadi, Hamidreza

“…Application of nanomaterials in our daily life is increasing, day in day out and concerns have raised about their toxicity for human and other organisms. In…”
Get full text

Activation of autophagy and suppression of apoptosis by dapagliflozin attenuates experimental inflammatory bowel disease in rats: Targeting AMPK/mTOR, HMGB1/RAGE and Nrf2/HO-1 pathways by Arab, Hany H., Al-Shorbagy, Muhammad Y., Saad, Muhammed A.

“…Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, has featured marked anti-inflammatory effects in murine models of myocardial…”
Get full text