Search Results - "Chelvarajan, Ralph L"
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The Role of MAPKs in B Cell Receptor-induced Down-regulation of Egr-1 in Immature B Lymphoma Cells
Published in The Journal of biological chemistry (29-12-2006)“…Cross-linking of the B cell receptor (BCR) on the immature B lymphoma cell line BKS-2 induces growth inhibition and apoptosis accompanied by rapid…”
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Neonatal immunity to polysaccharide antigens: role of B cells versus macrophages
Published in Nature reviews. Immunology (01-12-2004)Get full text
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Accessory cell defect in unresponsiveness of neonates and aged to polysaccharide vaccines
Published in Vaccine (15-10-2000)“…T independent antigens elicit antibody responses in the absence of carrier specific T helper cells but require signals from accessory cells (macrophages and…”
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Early events in B lymphocyte activation
Published in Current protocols in immunology (01-11-2003)“…B cell activation can be quantitated indirectly by assaying antibody production or directly by measuring cellular changes that occur immediately after exposure…”
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Neonatal Murine B Lymphocytes Respond to Polysaccharide Antigens in the Presence of IL-1 and IL-6
Published in The Journal of immunology (1950) (01-10-1998)“…Unlike adults, neonates are unable to respond to polysaccharide Ags, making them especially vulnerable to pathogenic encapsulated bacteria. Since the Ab…”
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CpG oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from anti-IgM-mediated growth inhibition by up-regulation of egr-1
Published in International immunology (01-06-1999)“…Cross-linking of the IgM antigen receptor on an immature B cell lymphoma (BKS-2) induces growth arrest and apoptosis. This is accompanied by down-regulation of…”
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Study of nicotine demethylation in Nicotiana otophora
Published in Journal of agricultural and food chemistry (01-06-1993)“…Microsomes from Nicotiana otophora catalyze the demethylation of nicotine to nornicotine in the presence of NADPH and oxygen. Activity was maximal at pH…”
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THE Class IA PI3-Kinase signaling Pathway: A Potential Target for Enhancing the Proinflammatory Cytokines in the Aged Macrophages (135.53)
Published in The Journal of immunology (1950) (01-04-2009)“…The elderly suffer from increased infections with Streptococcus pneumonia due to a reduced ability to produce antibodies to the capsular polysaccharide (CPS)…”
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CpG oligodeoxynucleotides overcome the unresponsiveness of neonatal B cells to stimulation with the thymus‐independent stimuli anti‐IgM and TNP‐Ficoll
Published in European journal of immunology (01-09-1999)“…Neonates are very vulnerable to pathogenic encapsulated bacteria due to their inability to mount an antibody response to capsular polysaccharides, which are…”
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