Search Results - "Chellappan, S. P."

Retraction Note: IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer by Guo, J., Kim, D., Gao, J., Kurtyka, C., Chen, H., Yu, C., Wu, D., Mittal, A., Beg, A. A., Chellappan, S. P., Haura, E. B., Cheng, J. Q.

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IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer by Guo, J, Kim, D, Gao, J, Kurtyka, C, Chen, H, Yu, C, Wu, D, Mittal, A, Beg, A A, Chellappan, S P, Haura, E B, Cheng, J Q

“…Serine/threonine kinase IKBKE is a newly identified oncogene; however, its regulation remains elusive. Here, we provide evidence that IKBKE is a downstream…”
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Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites by Joshi, B, Rastogi, S, Morris, M, Carastro, L M, DeCook, C, Seto, E, Chellappan, S P

“…Prohibitin is a 30 kDa growth suppressive protein that has pleiotropic functions in the cell. Although prohibitin has been demonstrated to have potent…”
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TNF-α response of vascular endothelial and vascular smooth muscle cells involve differential utilization of ASK1 kinase and p73 by Rastogi, S, Rizwani, W, Joshi, B, Kunigal, S, Chellappan, S P

“…Atherosclerosis involves a specialized inflammatory process regulated by an intricate network of cytokine and chemokine signaling. Atherosclerotic lesions lead…”
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The E2F transcription factor is a cellular target for the RB protein by Chellappan, S P, Hiebert, S, Mudryj, M, Horowitz, J M, Nevins, J R

“…Although it is generally believed that the product of the retinoblastoma susceptibility gene (RB1) is an important regulator of cell proliferation, the…”
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The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F by HIEBERT, S. W, CHELLAPPAN, S. P, HOROWITZ, J. M, NEVINS, J. R

“…Recent experiments have shown that the E2F transcription factor is in a complex with the RB1 gene product. The E2F-pRB complex can be reconstituted in an in…”
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Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60) by FREEMERMAN, A. J, VRANA, J. A, TOMBES, R. M, JIANG, H, CHELLAPPAN, S. P, FISHER, P. B, GRANT, S

“…The p21MDA6 gene product induces cell cycle arrest in p53-null human leukemic cells exposed to differentiation stimuli. We employed an HL-60 cell line stably…”
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Interactions of the p107 and Rb proteins with E2F during the cell proliferation response by Schwarz, J.K., Devoto, S.H., Smith, E.J., Chellappan, S.P., Jakoi, L., Nevins, J.R.

“…The E2F transcription factor is found in complexes with a variety of cellular proteins including the retinoblastoma tumor suppressor protein. Various assays…”
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Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression by SHENG WANG, FUSARO, Gina, PADMANABHAN, Jaya, CHELLAPPAN, Srikumar P

“…The potential tumor suppressor protein prohibitin can prevent cell proliferation and this required its binding to the Rb protein. Prohibitin could repress the…”
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RETRACTED ARTICLE: IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer by Guo, J, Kim, D, Gao, J, Kurtyka, C, Chen, H, Yu, C, Wu, D, Mittal, A, Beg, A A, Chellappan, S P, Haura, E B, Cheng, J Q

“…Serine/threonine kinase IKBKE is a newly identified oncogene; however, its regulation remains elusive. Here, we provide evidence that IKBKE is a downstream…”
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Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937) by Vrana, Julie A., Saunders, Aida M., Chellappan, Srikumar P., Grant, Steven

“…Bryostatin 1 and the phorbol ester, phorbol myristate acetate (PMA), both bind to and activate protein kinase C (PKC) but exhibit divergent biological actions…”
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Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family by ZHANG, Y, VENKATRAJ, V. S, FISCHER, S. G, WARBURTON, D, CHELLAPPAN, S. P

“…The TFDP genes encode a family of transcription factors that can form heterodimers with E2F family proteins in vivo. The E2F-TFDP transcription factors are…”
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A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosis by Joshi, Bharat, Ko, Danette, Ordonez-Ercan, Dalia, Chellappan, Srikumar P

“…Prohibitin is a potential tumor suppressor protein that can repress E2F-mediated transcription and arrest cell proliferation. We had shown previously that…”
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E2F transcription factor is a target for the RB protein and the cyclin A protein by Nevins, J R, Chellappan, S P, Mudryj, M, Hiebert, S, Devoto, S, Horowitz, J, Hunter, T, Pines, J

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Role of cyclin-dependent kinases and their inhibitors in cellular differentiation and development by Chellappan, S P, Giordano, A, Fisher, P B

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Raf-1 Physically Interacts with Rb and Regulates Its Function: a Link between Mitogenic Signaling and Cell Cycle Regulation by Wang, Sheng, Ghosh, Richik N., Chellappan, Srikumar P.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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DNA Octamer Element can confer E1A Trans-Activation, and Adenovirus Infection Results in a Stimulation of the DNA-Binding Activity of OTF-1/ NFIII Factor by Chellappan, Srikumar P., Nevins, Joseph R.

“…Adenovirus E1A-dependent trans-activation of viral transcription involves the utilization and alteration of multiple sequence-specific transcription factors…”
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Cloning and characterization of human DP2, a novel dimerization partner of E2F by Zhang, Y, Chellappan, S P

“…The transcription factor E2F consists of a family of proteins that bind to the sequence TTTCGCGC and regulate the expression of various cellular and viral…”
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The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human myeloid leukemia cells by CARTEE, Leanne, ZHILIANG WANG, DECKER, Roy H, CHELLAPPAN, Srikumar P, FUSARO, Gina, HIRSCH, Karen G, SANKALA, Heidi M, DENT, Paul, GRANT, Steven

“…Interactions between the cyclin-dependent kinase inhibitor (CDKI) flavopiridol (FP) and phorbol 12-myristate 13-acetate (PMA) were examined in U937 human…”
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HLA Class I-Mediated Induction of Cell Proliferation Involves Cyclin E-Mediated Inactivation of Rb Function and Induction of E2F Activity by Nath, Niharika, Bian, Hong, Reed, Elaine F, Chellappan, Srikumar P

“…Chronic rejection of transplanted organs is manifested as atherosclerosis of the blood vessels of the allograft. HLA class I Ags have been implicated to play a…”
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