Search Results - "Chellappan, Dinesh K."
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Targeting Cancer using Curcumin Encapsulated Vesicular Drug Delivery Systems
Published in Current pharmaceutical design (2021)“…Curcumin is a major curcuminoid present in turmeric. The compound is attributed to various therapeutic properties, which include anti-oxidant,…”
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Adenosine Receptors in Modulation of Central Nervous System Disorders
Published in Current pharmaceutical design (01-01-2019)“…The ubiquitous signaling nucleoside molecule, adenosine is found in different cells of the human body to provide its numerous pharmacological role. The…”
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3
Recent Trends in Rationally Designed Molecules as Kinase Inhibitors
Published in Current medicinal chemistry (01-01-2023)“…Protein kinases modulate the structure and function of proteins by adding phosphate groups to threonine, tyrosine, and serine residues. The phosphorylation…”
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Managing Apoptosis in Lung Diseases using Nano-assisted Drug Delivery System
Published in Current pharmaceutical design (01-01-2022)“…Several factors exist that limit the efficacy of lung cancer treatment. These may be tumor-specific delivery of therapeutics, airway geometry, humidity,…”
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Pharmaceutical Aspects of Green Synthesized Silver Nanoparticles: A Boon to Cancer Treatment
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…Silver nanoparticles (AgNPs) are among the most investigated nanostructures in recent years, which exhibit more challenging and promising qualities in…”
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Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
Published in MedComm (2020) (01-04-2023)“…Cancer is a disease associated with complex pathology and one of the most prevalent and leading reasons for mortality in the world. Current chemotherapy has…”
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Dietary Crocin is Protective in Pancreatic Cancer while Reducing Radiation-Induced Hepatic Oxidative Damage
Published in Nutrients (26-06-2020)“…Pancreatic cancer is one of the fatal causes of global cancer-related deaths. Although surgery and chemotherapy are standard treatment options, post-treatment…”
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Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression
Published in Current molecular pharmacology (01-01-2021)“…Hypoxia is an integral part of the tumor microenvironment, caused primarily due to rapidly multiplying tumor cells and a lack of proper blood supply. Among the…”
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Perfluorocarbons Therapeutics in Modern Cancer Nanotechnology for Hypoxiainduced Anti-tumor Therapy
Published in Current pharmaceutical design (2021)“…With an estimated failure rate of about 90%, immunotherapies that are intended for the treatment of solid tumors have caused an anomalous rise in the mortality…”
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An Appraisal of the Current Scenario in Vaccine Research for COVID-19
Published in Viruses (18-07-2021)“…The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With…”
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Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update
Published in Inflammopharmacology (01-08-2020)“…Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are amongst the leading causes of mortality and morbidity worldwide…”
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Molecular aspects of Omicron, vaccine development, and recombinant strain XE: A review
Published in Journal of medical virology (01-10-2022)“…The global pandemic of COVID‐19 began in December 2019 and is still continuing. The past 2 years have seen the emergence of several variants that were more…”
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RAAS blockers in hypertension posing a higher risk toward the COVID‐19
Published in Dermatologic therapy (01-07-2020)Get full text
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Dynamics of Prolyl Hydroxylases Levels During Disease Progression in Experimental Colitis
Published in Inflammation (01-12-2019)“…Hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitors are shown to be protective in several models of inflammatory bowel disease (IBD). However,…”
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Potentialities of aptasensors in cancer diagnosis
Published in Materials letters (01-02-2022)“…•Cancer is a life-threatening disease that affects people all over the world.•Biosensor a beneficial tool for the early identification and detection of a…”
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Tumor suppressor role of miR-503
Published in Panminerva medica (01-03-2018)“…MicroRNAs (miRNAs) are non-coding RNAs of around 20-25 nucleotides in length with highly conserved characteristics. They moderate post-transcriptional…”
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Anti-bacterial activity of inorganic nanomaterials and their antimicrobial peptide conjugates against resistant and non-resistant pathogens
Published in International journal of pharmaceutics (30-08-2020)“…[Display omitted] This review details the antimicrobial applications of inorganic nanomaterials of mostly metallic form, and the augmentation of activity by…”
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Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective
Published in Chemico-biological interactions (01-07-2020)“…The apparent predicament of the representative chemotherapy for managing respiratory distress calls for an obligatory deliberation for identifying the…”
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Nanocarriers: more than tour de force for thymoquinone
Published in Expert opinion on drug delivery (02-04-2020)“…: Thymoquinone (TQ), 2-isopropyl-5-methylbenzo-1, 4-quinone, the main active constituent of Nigella sativa (NS) plant, has been proven to be of great…”
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Interleukin-13: A pivotal target against influenza-induced exacerbation of chronic lung diseases
Published in Life sciences (1973) (15-10-2021)“…Non-communicable, chronic respiratory diseases (CRDs) affect millions of individuals worldwide. The course of these CRDs (asthma, chronic obstructive pulmonary…”
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