Search Results - "Chehade, Rania"

Association between immune-related side effects and efficacy and benefit of immune checkpoint inhibitors – A systematic review and meta-analysis by Hussaini, Syed, Chehade, Rania, Boldt, Ronald Gabriel, Raphael, Jacques, Blanchette, Phillip, Maleki Vareki, Saman, Fernandes, Ricardo

“…•Immune checkpoint inhibitors can induce immune-related adverse events (irAEs), potentially life-threatening.•There is evidence suggesting a potential…”
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Esophageal carcinoma: Towards targeted therapies by Fatehi Hassanabad, Ali, Chehade, Rania, Breadner, Daniel, Raphael, Jacques

“…Background Patients with esophageal cancer are confronted with high mortality rates. Whether it is esophageal squamous cell carcinoma (ESCC) or esophageal…”
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PARP inhibitors in non-ovarian gynecologic cancers by Fernandes, Italo, Chehade, Rania, MacKay, Helen

“…Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) have transformed the treatment of ovarian cancer, particularly benefiting patients whose tumors harbor…”
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Pan-Canadian Analysis of Practice Patterns in Small Cell Carcinoma of the Cervix: Insights from a Multidisciplinary Survey by Fan, Kevin Yijun, Chehade, Rania, Wang, Andrew Yuanbo, Sachdeva, Anjali, MacKay, Helen J, Taggar, Amandeep S

“…Small-cell neuroendocrine carcinoma of the cervix (SCNECC) is a rare cancer with poor prognosis, with limited data to guide its treatment. The objective of…”
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Uninterrupted Sedentary Behavior Downregulates BRCA1 Gene Expression by Pettapiece-Phillips, Rachael, Kotlyar, Max, Chehade, Rania, Salmena, Leonardo, Narod, Steven A, Akbari, Mohammad, Jurisica, Igor, Kotsopoulos, Joanne

“…BRCA1 mutation carriers face a high lifetime risk of developing breast cancer. Physical activity induces broad transcriptional changes, and multiple studies…”
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Practice patterns in the treatment of small cell carcinoma of the cervix: Analysis of a Canadian multidisciplinary survey by Fan, Kevin Yijun, Chehade, Rania, Wang, Andrew Yuanbo, Sachdeva, Anjali, Mackay, Helen, Taggar, Amandeep

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HER2-low breast cancer brain metastases: Incidence and treatment implications by Chehade, Rania, Nofech-Mozes, Sharon, Plotkin, Anna, Moravan, Veronika, Jerzak, Katarzyna Joanna

“…2035 Background: Brain metastases (BrM) are a major cause of morbidity and mortality among women with breast cancer (BC). Central nervous system…”
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Abstract P5-13-17: PD-L1 expression in breast to brain metastases by Chehade, Rania, Qazi, Maleeha A, Ennis, Marguerite, Nofech-Mozes, Sharon, Jerzak, Katarzyna

“…Abstract Background Brain metastases (BrM) are a major cause of morbidity and mortality in women with breast cancer. Immunotherapy has the potential for…”
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Advances in Vulvar Cancer Biology and Management by Chehade, Rania, Jerzak, Katarzyna J, Tavanger, Farideh, Plotkin, Anna, Gien, Lilian T, Leung, Eric, Mackay, Helen

“…Vulvar squamous cell carcinoma (VSCC), a rare gynecologic malignancy, has been rising in incidence. Molecular classification on the basis of human papilloma…”
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Treatment Patterns and Outcomes of Women with Symptomatic and Asymptomatic Breast Cancer Brain Metastases: A Single‐Center Retrospective Study by Gao, Yizhuo Kelly, Kuksis, Markus, Id Said, Badr, Chehade, Rania, Kiss, Alex, Tran, William, Sickandar, Faisal, Sahgal, Arjun, Warner, Ellen, Soliman, Hany, Jerzak, Katarzyna J.

“…Background Breast cancer is the most common cancer among women worldwide and the second leading cause of brain metastases (BrM). We assessed the treatment…”
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Real-world outcomes of breast cancer patients with brain metastases treated with radiotherapy in Ontario: A population-based study by Jerzak, Katarzyna Joanna, Rosen, Michael, Wang, Xin Y, Chehade, Rania, Zhang, Bo, Saskin, Refik, Das, Sunit, Soliman, Hany, Sahgal, Arjun, Chan, Kelvin K.

“…Abstract only 2027 Background: Brain Metastases (BrM) are a major cause of morbidity and mortality in patients with metastatic breast cancer (MBC). Real-word…”
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BMRK-05 ASSOCIATION BETWEEN HER2-LOW STATUS AND TIME TO DEVELOPMENT OF BRAIN METASTASES AMONG PATIENTS WITH BREAST CANCER: A RETROSPECTIVE COHORT STUDY by Yijun Fan, Kevin, Chehade, Rania, Fernandes, Italo, Moravan, Veronika, Jerzak, Katarzyna

“…Abstract BACKGROUND Brain metastases (BrM) develop in a high proportion of patients with breast cancer. We aimed to investigate the association between HER2…”
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Androgen Receptor Is Expressed in the Majority of Breast Cancer Brain Metastases and Is Subtype-Dependent by Fan, Kevin Yijun, Chehade, Rania, Qazi, Maleeha, Moravan, Veronika, Nofech-Mozes, Sharon, Jerzak, Katarzyna J

“…We aimed to evaluate the expression of the "targetable" androgen receptor (AR) in breast cancer brain metastases (BrM). An established, retrospective…”
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Brain Metastases in the Setting of Stable Versus Progressing Extracranial Disease Among Patients With Metastatic Breast Cancer by Kojundzic, Isabella, Chehade, Rania, Gonzalez, Carlos A. Carmona, Fritz, Jamie, Moravan, Veronika, Sahgal, Arjun, Warner, Ellen, Das, Sunit, Jerzak, Katarzyna J.

“…Women with metastatic breast cancer (BC) are at risk of developing brain metastases (BrM), which may result in significant morbidity and mortality. Given the…”
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HER2-LOW BREAST CANCER BRAIN METASTASES: INCIDENCE AND TREATMENT IMPLICATIONS by Chehade, Rania, Nofech-Mozes, Sharon, Plotkin, Anna, Moravan, Veronika, Jerzak, Katarzyna J

“…Abstract Brain metastases (BrM) are a major cause of morbidity and mortality among women with breast cancer (BC). Central nervous system (CNS)-penetrating…”
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EXPRESSION OF ANDROGEN RECEPTOR IN BREAST CANCER BRAIN METASTASES by Fan, Kevin Yijun, Chehade, Rania, Qazi, Maleeha A, Moravan, Veronika, Nofech-Moses, Sharon, Jerzak, Katarzyna J

“…Abstract Given availability of central nervous system (CNS)-penetrant systemic therapies that target the androgen receptor (AR), we evaluated the expression of…”
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Human Epidermal Growth Factor Receptor 2-Low Breast Cancer Brain Metastases: An Opportunity for Targeted Systemic Therapies in a High-Need Patient Population by Chehade, Rania, Nofech-Mozes, Sharon, Plotkin, Anna, Fan, Kevin Yijun, Das, Sunit, Sahgal, Arjun, Moravan, Veronika, Jerzak, Katarzyna Joanna

“…Trastuzumab deruxtecan is a new treatment option for patients with advanced human epidermal growth factor receptor 2 (HER2)-low breast cancer (BC). Although…”
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Appraisal of Systemic Treatment Strategies in Early HER2-Positive Breast Cancer—A Literature Review by Giffoni de Mello Morais Mata, Danilo, Chehade, Rania, Hannouf, Malek B, Raphael, Jacques, Blanchette, Phillip, Al-Humiqani, Abdullah, Ray, Monali

“…Background: The overexpression of the human epidermal growth factor receptor 2 (HER2+) accounts for 15–20% of all breast cancer phenotypes. Even after the…”
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A Comparative Analysis to Determine Clinical Factors Influencing Technicity Index Between Hospitals [3J] by Pelinska, Gabriela, Vilayil, Ruth, Chehade, Rania, Baird, Jennifer, Schulz, Jane, Brown, Ronald

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Abstract PO3-14-10: A single-center prospective cohort study to evaluate circulating tumor cells as a monitoring tool in women with breast cancer treated with neoadjuvant chemotherapy: final results of baseline data by Chehade, Rania, Jain, Arushi, Moravan, Veronika, Caro, Giuseppe Di, Slade, Megan, Hartmann, Nadine, Wenstrup, Rick, Lohmann, Ana Elisa, Tran, William, Jerzak, Katarzyna

“…Abstract Background: The presence of liquid biomarkers such as circulating tumor cells (CTCs) among women undergoing neoadjuvant chemotherapy (NAC) for breast…”
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