Search Results - "Chehab, F"

General scheme to reduce the knee adduction moment by modifying a combination of gait variables by Favre, Julien, Erhart-Hledik, Jennifer C., Chehab, Eric F., Andriacchi, Thomas P.

“…ABSTRACT Reducing the knee adduction moment (KAM) is a promising treatment for medial compartment knee osteoarthritis (OA). Although several gait modifications…”
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Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia by Stieglitz, Elliot, Mazor, Tali, Olshen, Adam B., Geng, Huimin, Gelston, Laura C., Akutagawa, Jon, Lipka, Daniel B., Plass, Christoph, Flotho, Christian, Chehab, Farid F., Braun, Benjamin S., Costello, Joseph F., Loh, Mignon L.

“…Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative disorder of childhood caused by mutations in the Ras pathway. Outcomes in JMML vary markedly…”
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Microbiome-derived metabolites in early to mid-pregnancy and risk of gestational diabetes: a metabolome-wide association study by Susarla, Sita Manasa, Fiehn, Oliver, Thiele, Ines, Ngo, Amanda L, Barupal, Dinesh K, Chehab, Rana F, Ferrara, Assiamira, Zhu, Yeyi

“…Pre-diagnostic disturbances in the microbiome-derived metabolome have been associated with an increased risk of diabetes in non-pregnant populations. However,…”
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A systematic review of high impact CpG sites and regions for MGMT methylation in glioblastoma [A systematic review of MGMT methylation in GBM] by Gibson, David, Vo, Anh Huan, Lambing, Hannah, Bhattacharya, Prithanjan, Tahir, Peggy, Chehab, Farid F, Butowski, Nicholas

“…MGMT (O 6 -methylguanine-DNA methyltransferase) promoter methylation is a commonly assessed prognostic marker in glioblastoma (GBM). Epigenetic silencing of…”
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Gender equity in planning, development and management of human resources for health: a scoping review by El Arnaout, Nour, Chehab, Rana F, Rafii, Bayan, Alameddine, Mohamad

“…Gender equity remains a challenge across various labor markets with the health market being no exception. Despite the increased influx of women into health…”
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Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin by Chehab, Farid F, Lim, Mary E, Lu, Ronghua

“…The sterility of male and female homozygous ob/ob mice is a recognized feature of the ob mutation (1). Whereas ob/ob males can occasionally reproduce if…”
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Molecular assessment of pretransplant chemotherapy in the treatment of juvenile myelomonocytic leukemia by Hecht, Anna, Meyer, Julia, Chehab, Farid F., White, Kristie L., Magruder, Kevin, Dvorak, Christopher C., Loh, Mignon L., Stieglitz, Elliot

“…Background Despite the intensity of hematopoietic stem cell transplantation (HCT), relapse remains the most common cause of death in juvenile myelomonocytic…”
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Exclusive breastfeeding during the 40-day rest period and at six months in Lebanon: a cross-sectional study by Chehab, Rana F, Nasreddine, Lara, Zgheib, Racha, Forman, Michele R

“…Exclusive breastfeeding is recommended for the first 6 months of life with well-established benefits to the mother and child. The traditional practice of the…”
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LNK/ SH2B3 as a novel driver in juvenile myelomonocytic leukemia by Wintering, Astrid, Hecht, Anna, Meyer, Julia, Wong, Eric B, Hübner, Juwita, Abelson, Sydney, Feldman, Kira, Kennedy, Vanessa E, Peretz, Cheryl A C, French, Deborah L, Maguire, Jean Ann, Jobaliya, Chintan, Vasquez, Marta Rojas, Desai, Sunil, Dulman, Robin, Nemecek, Eneida, Haines, Hilary, Hammad, Mahmoud, El Haddad, Alaa, Kogan, Scott C, Abdullaev, Zied, Chehab, Farid F, Tasian, Sarah K, Smith, Catherine C, Loh, Mignon L, Stieglitz, Elliot

“…Mutations in five canonical Ras pathway genes (NF1, NRAS, KRAS, PTPN11 and CBL) are detected in nearly 90% of patients with juvenile myelomonocytic leukemia…”
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A scoping review of reporting 'Ethical Research Practices' in research conducted among refugees and war-affected populations in the Arab world by Makhoul, Jihad, Chehab, Rana F, Shaito, Zahraa, Sibai, Abla M

“…Ethical research conduct is a cornerstone of research practice particularly when research participants include vulnerable populations. This study mapped the…”
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Validity and Reproducibility of a Culture-Specific Food Frequency Questionnaire in Lebanon by El Sayed Ahmad, Raeda, Baroudi, Mariam, Shatila, Hibeh, Nasreddine, Lara, Chokor, Fatima Al Zahraa, Chehab, Rana F, Forman, Michele R, Naja, Farah

“…This study aims to assess the validity and reproducibility of a culture-specific semi-quantitative food frequency questionnaire (FFQ) for Lebanese adults. The…”
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Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake by Zhu, Jun, Mounzih, Khalid, Chehab, Eric F., Mitro, Nico, Saez, Enrique, Chehab, Farid F.

“…The Forkhead transcription factors FoxO1, FoxO3a, and FoxO4 play a prominent role in regulating cell survival and cell cycle. Whereas FOXO1 was shown to…”
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FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2α at the CYP51 promoter by Zhu, Jun, Jiang, Xiangning, Chehab, Farid F.

“…The late steps of cholesterol biosynthesis are oxygen demanding, requiring eleven oxygen molecules per synthesized cholesterol molecule. A key enzymatic…”
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Early Onset of Reproductive Function in Normal Female Mice Treated with Leptin by Chehab, Farid F., Mounzih, Khalid, Lu, Ronghua, Lim, Mary E.

“…Numerous studies have revealed an association between nutritional status, adiposity, and reproductive maturity. The role of leptin, a hormone secreted from…”
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Leptin Treatment Rescues the Sterility of Genetically Obese ob/ob Males by Mounzih, Khalid, Lu, Ronghua, Chehab, Farid F.

“…Abstract Leptin, a hormone secreted from white adipose tissue, has been shown to normalize the body weight of ob/ob but not db/db mice as postulated by Coleman…”
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Longitudinal Associations of Plasma Phospholipid Fatty Acids in Pregnancy with Neonatal Anthropometry: Results from the NICHD Fetal Growth Studies-Singleton Cohort by Wang, Emily, Zhu, Yeyi, Chehab, Rana F, Wu, Jing, Hinkle, Stefanie N, Weir, Natalie L, Bremer, Andrew A, Yang, Jiaxi, Chen, Zhen, Tsai, Michael Y, Zhang, Cuilin

“…Despite increasing interest in the health effects of polyunsaturated FAs (PUFAs), their roles in fetal and neonatal growth remain understudied. Within the…”
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Prenatal vitamin C and fish oil supplement use are associated with human milk microbiota composition in the Canadian CHILD Cohort Study by Chehab, Rana F., Fehr, Kelsey, Moossavi, Shirin, Subbarao, Padmaja, Moraes, Theo J., Mandhane, Piushkumar, de Souza, Russell J., Turvey, Stuart E., Khafipour, Ehsan, Azad, Meghan B., Forman, Michele R.

“…Maternal diet may modulate human milk microbiota, but the effects of nutritional supplements are unknown. We examined the associations of prenatal diet and…”
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First report of a deletion encompassing an entire exon in the homogentisate 1,2-dioxygenase gene causing alkaptonuria by Zouheir Habbal, Mohammad, Bou-Assi, Tarek, Zhu, Jun, Owen, Renius, Chehab, Farid F

“…Alkaptonuria is often diagnosed clinically with episodes of dark urine, biochemically by the accumulation of peripheral homogentisic acid and molecularly by…”
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Leptin as a regulator of adipose mass and reproduction by Chehab, Farid F

“…Leptin, an adipocyte-derived hormone, informs neuroendocrine pathways about the status of energy stores in adipose tissue. The integration of this peripheral…”
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Surgical management of recto-vaginal fistula (about 6 cases) by El Karouachi, A., Hajri, A., El Jai, S.R., Erguibi, D., Boufettal, R., Chehab, F.

“…Recto-vaginal fistula (RVF) is defined as a pathological epithelialized communication between the posterior wall of the vagina and the anterior wall of the…”
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