Search Results - "Cheetham, Timothy D"

Is ongoing testosterone required after pubertal induction in Duchenne muscular dystrophy? by Wood, Claire L, Hollingsworth, Kieren G, Bokaie, Edrina, Hughes, Eric, Muni-Lofra, Robert, Mayhew, Anna, Mitchell, Rod T, Guglieri, Michela, McElvaney, Joseph, Cheetham, Timothy D, Straub, Volker

“…Glucocorticoids (GC) reduce inflammation and preserve muscle function in boys with Duchenne muscular dystrophy (DMD) but cause pubertal delay. Pubertal…”
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Genomic Polymorphism at the Interferon-Induced Helicase (IFIH1) Locus Contributes to Graves’ Disease Susceptibility by Sutherland, Alison, Davies, Jocelyn, Owen, Catherine J., Vaikkakara, Suresh, Walker, Christine, Cheetham, Timothy D., James, R. Andrew, Perros, Petros, Donaldson, Peter T., Cordell, Heather J., Quinton, Richard, Pearce, Simon H. S.

“…Context: A recent large-scale analysis of nonsynonymous coding polymorphisms showed strong evidence that an alanine to threonine amino acid change at codon 946…”
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Initial response of young people with thyrotoxicosis to block and replace or dose titration thionamide by Wood, Claire L, Morrison, Niamh, Cole, Michael, Donaldson, Malcolm, Dunger, David B, Wood, Ruth, Pearce, Simon H S, Cheetham, Timothy D

“…Objective Patients with thyrotoxicosis are treated with anti-thyroid drug (ATD) using block and replace (BR) or a smaller, titrated dose of ATD (dose…”
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How do childhood diagnoses of type 1 diabetes cluster in time? by Muirhead, Colin R, Cheetham, Timothy D, Court, Simon, Begon, Michael, McNally, Richard J Q

“…Previous studies have indicated that type 1 diabetes may have an infectious origin. The presence of temporal clustering-an irregular temporal distribution of…”
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Catch-up growth and metabolic outcomes in adolescents born preterm by Embleton, Nicholas D, Korada, Murthy, Wood, Claire L, Pearce, Mark S, Swamy, Ravi, Cheetham, Timothy D

“…BackgroundAccelerated infant weight gain in individuals born full term is linked to cardiovascular risk in adulthood, but data in those born preterm are…”
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Sexual health and fertility in Duchenne muscular dystrophy—An exploratory study by Hoskin, Janet, Cheetham, Timothy D, Mitchell, Rod T, Wong, Sze Choong, Wood, Claire L

“…Introduction/Aims Recent clinical guidelines recommend that adolescents with Duchenne muscular dystrophy (DMD) who are on daily glucocorticoid treatment should…”
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Quality of Life in Children and Young People With Congenital Adrenal Hyperplasia—UK Nationwide Multicenter Assessment by Lawrence, Neil Richard, Bacila, Irina, Dawson, Jeremy, Mahdi, Sundus, Alvi, Sabah, Cheetham, Timothy D, Crowne, Elizabeth, Das, Urmi, Dattani, Mehul Tulsidas, Davies, Justin H, Gevers, Evelien, Krone, Ruth E, Patel, Leena, Randell, Tabitha, Ryan, Fiona J, Keevil, Brian, Ahmed, S Faisal, Krone, Nils P

“…Abstract Context Quality of life (QoL) has been inconsistently reported in children and young people (CYP) with congenital adrenal hyperplasia (CAH). Objective…”
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Pubertal induction in adolescents with DMD is associated with high satisfaction, gonadotropin release and increased muscle contractile surface area by Wood, Claire L, Hollingsworth, Kieren G, Hughes, Eric, Punniyakodi, Sadhanandham, Muni-Lofra, Robert, Mayhew, Anna, Mitchell, Rod T, Guglieri, Michela, Cheetham, Timothy D, Straub, Volker

“…Background Pharmacological doses of glucocorticoids (GC) reduce inflammation and preserve muscle function in boys with Duchenne muscular dystrophy (DMD)…”
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Health status of children and young persons with congenital adrenal hyperplasia in the UK (CAH-UK): a cross-sectional multi-centre study by Bacila, Irina, Lawrence, Neil Richard, Mahdi, Sundus, Alvi, Sabah, Cheetham, Timothy D, Crowne, Elizabeth, Das, Urmi, Dattani, Mehul Tulsidas, Davies, Justin H, Gevers, Evelien, Krone, Ruth E, Kyriakou, Andreas, Patel, Leena, Randell, Tabitha, Ryan, Fiona J, Keevil, Brian, Ahmed, S Faisal, Krone, Nils P

“…Objective There is limited knowledge on the onset of comorbidities in congenital adrenal hyperplasia (CAH) during childhood. We aimed to establish the health…”
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2022 European Thyroid Association Guideline for the management of pediatric Graves’ disease by Mooij, Christiaan F, Cheetham, Timothy D, Verburg, Frederik A, Eckstein, Anja, Pearce, Simon H, Léger, Juliane, van Trotsenburg, A S Paul

“…Hyperthyroidism caused by Graves’ disease (GD) is a relatively rare disease in children. Treatment options are the same as in adults – antithyroid drugs (ATD),…”
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Randomised trial of block and replace vs dose titration thionamide in young people with thyrotoxicosis by Wood, Claire L, Cole, Michael, Donaldson, Malcolm, Dunger, David B, Wood, Ruth, Morrison, Niamh, Matthews, John N S, Pearce, Simon H S, Cheetham, Timothy D

“…Objective First-line treatment of thyrotoxicosis in young people is thionamide anti-thyroid drug (ATD) in a blocking dose with levothyroxine replacement (block…”
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The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency: a case series by Sun, Min, Mueller, Jonathan W, Gilligan, Lorna C, Taylor, Angela E, Shaheen, Fozia, Noczyńska, Anna, T’Sjoen, Guy, Denvir, Louise, Shenoy, Savitha, Fulton, Piers, Cheetham, Timothy D, Gleeson, Helena, Rahman, Mushtaqur, Krone, Nils P, Taylor, Norman F, Shackleton, Cedric H L, Arlt, Wiebke, Idkowiak, Jan

“…Context 17α-Hydroxylase/17,20-lyase deficiency (17OHD) caused by mutations in the CYP17A1 gene is a rare form of congenital adrenal hyperplasia typically…”
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Expanding the Spectrum of Mutations in GH1 and GHRHR: Genetic Screening in a Large Cohort of Patients with Congenital Isolated Growth Hormone Deficiency by Alatzoglou, Kyriaki S., Turton, James P., Kelberman, Daniel, Clayton, Peter E., Mehta, Ameeta, Buchanan, Charles, Aylwin, Simon, Crowne, Elisabeth C., Christesen, Henrik T., Hertel, Niels T., Trainer, Peter J., Savage, Martin O., Raza, Jamal, Banerjee, Kausik, Sinha, Sunil K., Ten, Svetlana, Mushtaq, Talat, Brauner, Raja, Cheetham, Timothy D., Hindmarsh, Peter C., Mullis, Primus E., Dattani, Mehul T.

“…Context: It is estimated that 3–30% of cases with isolated GH deficiency (IGHD) have a genetic etiology, with a number of mutations being reported in GH1 and…”
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Should radioiodine be the first-line treatment for paediatric Graves' disease? by West, James D, Cheetham, Timothy D, Dane, Carole, Natarajan, Anuja

“…Debate exists regarding the optimal treatment strategy for paediatric Graves' disease with radioiodine (RAI), and surgery, usually reserved for failure of…”
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Predicted Benign and Synonymous Variants in CYP11A1 Cause Primary Adrenal Insufficiency Through Missplicing by Maharaj, Avinaash, Buonocore, Federica, Meimaridou, Eirini, Ruiz-Babot, Gerard, Guasti, Leonardo, Peng, Hwei-Ming, Capper, Cameron P, Burgos-Tirado, Neikelyn, Prasad, Rathi, Hughes, Claire R, Maudhoo, Ashwini, Crowne, Elizabeth, Cheetham, Timothy D, Brain, Caroline E, Suntharalingham, Jenifer P, Striglioni, Niccolò, Yuksel, Bilgin, Gurbuz, Fatih, Gupta, Sangay, Lindsay, Robert, Couch, Robert, Spoudeas, Helen A, Guran, Tulay, Johnson, Stephanie, Fowler, Dallas J, Conwell, Louise S, McInerney-Leo, Aideen M, Drui, Delphine, Cariou, Bertrand, Lopez-Siguero, Juan P, Harris, Mark, Duncan, Emma L, Hindmarsh, Peter C, Auchus, Richard J, Donaldson, Malcolm D, Achermann, John C, Metherell, Louise A

“…Abstract Primary adrenal insufficiency (PAI) is a potentially life-threatening condition that can present with nonspecific features and can be difficult to…”
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AIRE is not essential for the induction of human tolerogenic dendritic cells by Crossland, Katherine L., Abinun, Mario, Arkwright, Peter D., Cheetham, Timothy D., Pearce, Simon H., Hilkens, Catharien M. U., Lilic, Desa

“…Loss-of-function mutations of the Autoimmune Regulator (AIRE) gene results in organ-specific autoimmunity and disease Autoimmune Polyendocrinopathy type 1…”
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Growth and metabolic outcome in adolescents born preterm (GROWMORE): follow-up protocol for the Newcastle Preterm Birth GRowth study (PTBGS) by Wood, Claire L, Tinnion, Robert J, Korada, S Murthy, Cheetham, Timothy D, Relton, Caroline L, Cooke, Richard J, Pearce, Mark S, Hollingsworth, Kieren G, Trenell, Michael I, Embleton, Nicholas D

“…Preterm infants represent up to 10% of births worldwide and have an increased risk of adverse metabolic outcomes in later life. Early life exposures are key…”
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Establishing a registry of children and young people with diabetes in north east England and north Cumbria by Blakey, Karen, Johnson, Gillian, McNally, Richard JQ, Court, Simon, Potts, Adam, Stephenson, Carolyn, Lamb, Bill, Cheetham, Timothy D

“…The incidence of type 1 diabetes and type 2 diabetes in children and adolescents is rising. The associated public health burden is substantial with major…”
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Rarer syndromes characterized by hypogonadotropic hypogonadism by Aminzadeh, Majid, Kim, Hyung-Goo, Layman, Lawrence C, Cheetham, Timothy D

“…Hypogonadotropic hypogonadism (HH) secondary to hypothalamic gonadotropin-releasing hormone deficiency is a notable feature of a number of rare syndromes,…”
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Hypertonic saline test for the investigation of posterior pituitary function by Mohn, Angelika, Acerini, Carlo L, Cheetham, Timothy D, Lightman, Stafford L, Dunger, David B

“…The hypertonic saline test is a useful technique for distinguishing partial diabetes insipidus from psychogenic polydipsia, and for the diagnosis of complex…”
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