Search Results - "Cheeseman, T"

Oxr1 is essential for protection against oxidative stress-induced neurodegeneration by Oliver, Peter L, Finelli, Mattéa J, Edwards, Benjamin, Bitoun, Emmanuelle, Butts, Darcy L, Becker, Esther B E, Cheeseman, Michael T, Davies, Ben, Davies, Kay E

“…Oxidative stress is a common etiological feature of neurological disorders, although the pathways that govern defence against reactive oxygen species (ROS) in…”
Get full text

Understanding the aetiology and resolution of chronic otitis media from animal and human studies by Bhutta, Mahmood F, Thornton, Ruth B, Kirkham, Lea-Ann S, Kerschner, Joseph E, Cheeseman, Michael T

“…Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue…”
Get full text

The Southern Ocean Exchange: porous boundaries between humpback whale breeding populations in southern polar waters by Marcondes, M. C. C., Cheeseman, T., Jackson, J. A., Friedlaender, A. S., Pallin, L., Olio, M., Wedekin, L. L., Daura-Jorge, F. G., Cardoso, J., Santos, J. D. F., Fortes, R. C., Araújo, M. F., Bassoi, M., Beaver, V., Bombosch, A., Clark, C. W., Denkinger, J., Boyle, A., Rasmussen, K., Savenko, O., Avila, I. C., Palacios, D. M., Kennedy, A. S., Sousa-Lima, R. S.

“…Humpback whales ( Megaptera novaeangliae ) are a cosmopolitan species and perform long annual migrations between low-latitude breeding areas and high-latitude…”
Get full text

WHAT IDENTIFIES A WHALE BY ITS FLUKE? ON THE BENEFIT OF INTERPRETABLE MACHINE LEARNING FOR WHALE IDENTIFICATION by Kierdorf, J., Garcke, J., Behley, J., Cheeseman, T., Roscher, R.

“…Interpretable and explainable machine learning have proven to be promising approaches to verify the quality of a data-driven model in general as well as to…”
Get full text

Transcript Analysis Reveals a Hypoxic Inflammatory Environment in Human Chronic Otitis Media With Effusion by Bhutta, Mahmood F, Lambie, Jane, Hobson, Lindsey, Williams, Debbie, Tyrer, Hayley E, Nicholson, George, Brown, Steve D M, Brown, Helen, Piccinelli, Chiara, Devailly, Guillaume, Ramsden, James, Cheeseman, Michael T

“…Chronic otitis media with effusion (COME) is the most common cause of childhood hearing loss in the developed world. Underlying pathophysiology is not well…”
Get full text

A trans-Pacific movement reveals regular migrations of humpback whales Megaptera novaeangliae between Russia and Mexico by Ransome, N, Frisch-Jordán, A, Titova, OV, Filatova, OA, Hill, MC, Cheeseman, T, Bradford, AL, Urbán R, J, Martínez-Loustalot, P, Calambokidis, J, Medrano-González, L, Burdin, AM, Fedutin, ID, Loneragan, NR, Smith, JN

“…Humpback whales Megaptera novaeangliae undertake extensive annual migrations, have complex migratory patterns, and have held several mammalian long-distance…”
Get full text

A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse by Hood, Derek, Moxon, Richard, Purnell, Tom, Richter, Caroline, Williams, Debbie, Azar, Ali, Crompton, Michael, Wells, Sara, Fray, Martin, Brown, Steve D M, Cheeseman, Michael T

“…Acute otitis media, inflammation of the middle ear, is the most common bacterial infection in children and, as a consequence, is the most common reason for…”
Get full text

HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants by Cheeseman, Michael T, Tyrer, Hayley E, Williams, Debbie, Hough, Tertius A, Pathak, Paras, Romero, Maria R, Hilton, Helen, Bali, Sulzhan, Parker, Andrew, Vizor, Lucie, Purnell, Tom, Vowell, Kate, Wells, Sara, Bhutta, Mahmood F, Potter, Paul K, Brown, Steve D M

“…Otitis media with effusion (OME) is the commonest cause of hearing loss in children, yet the underlying genetic pathways and mechanisms involved are…”
Get full text

Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia by Harding, Brian, Lemos, Manuel C, Reed, Anita A C, Walls, Gerard V, Jeyabalan, Jeshmi, Bowl, Michael R, Tateossian, Hilda, Sullivan, Nicky, Hough, Tertius, Fraser, William D, Ansorge, Olaf, Cheeseman, Michael T, Thakker, Rajesh V

“…Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized in man by parathyroid, pancreatic, pituitary and adrenal tumours…”
Get full text

Searching for humpback whales in a historical whaling hotspot of the Coral Sea, South Pacific by Garrigue, C, Derville, S, Bonneville, C, Baker, CS, Cheeseman, T, Millet, L, Paton, D, Steel, D

“…Humpback whales Megaptera novaeangliae were severely depleted by commercial whaling. Understanding key factors in their recovery is a crucial step for their…”
Get full text

Unraveling the genetics of otitis media: from mouse to human and back again by Rye, Marie S, Bhutta, Mahmood F, Cheeseman, Michael T, Burgner, David, Blackwell, Jenefer M, Brown, Steve D. M, Jamieson, Sarra E

“…Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity. Acute OM and…”
Get full text

Activating Calcium-Sensing Receptor Mutation in the Mouse Is Associated with Cataracts and Ectopic Calcification by Hough, Tertius A., Bogani, Debora, Cheeseman, Michael T., Favor, Jack, Nesbit, M. Andrew, Thakker, Rajesh V., Lyon, Mary F.

“…The extracellular calcium-sensing receptor (CaSR) plays a pivotal role in the regulation of extracellular calcium such that abnormalities, which result in a…”
Get full text

A mouse model for osseous heteroplasia by Cheeseman, Michael T, Vowell, Kate, Hough, Tertius A, Jones, Lynn, Pathak, Paras, Tyrer, Hayley E, Kelly, Michelle, Cox, Roger, Warren, Madhuri V, Peters, Jo

“…GNAS/Gnas encodes G(s)α that is mainly biallelically expressed but shows imprinted expression in some tissues. In Albright Hereditary Osteodystrophy (AHO)…”
Get full text

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis by Esapa, Christopher T, Head, Rosie A, Jeyabalan, Jeshmi, Evans, Holly, Hough, Tertius A, Cheeseman, Michael T, McNally, Eugene G, Carr, Andrew J, Thomas, Gethin P, Brown, Matthew A, Croucher, Peter I, Brown, Steve D M, Cox, Roger D, Thakker, Rajesh V

“…Mutations of UDP-N-acetyl-alpha-D-galactosamine polypeptide N-acetyl galactosaminyl transferase 3 (GALNT3) result in familial tumoural calcinosis (FTC) and the…”
Get full text

Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media by Parkinson, Nicholas, Hardisty-Hughes, Rachel E, Tateossian, Hilda, Tsai, Hsun-Tien, Brooker, Debra, Morse, Sue, Lalane, Zuzanna, MacKenzie, Francesca, Fray, Martin, Glenister, Pete, Woodward, Anne-Marie, Polley, Sian, Barbaric, Ivana, Dear, Neil, Hough, Tertius A, Hunter, A Jackie, Cheeseman, Michael T, Brown, Steve D M

“…Otitis media (OM), inflammation of the middle ear, remains the most common cause of hearing impairment in children. It is also the most common cause of surgery…”
Get full text

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus by Pridans, Clare, Raper, Anna, Davis, Gemma M, Alves, Joana, Sauter, Kristin A, Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J, Clohisey, Sara, Bush, Stephen J, Rojo, Rocío, Lisowski, Zofia M, Wallace, Robert, Grabert, Kathleen, Upton, Kyle R, Tsai, Yi Ting, Brown, Deborah, Smith, Lee B, Summers, Kim M, Mabbott, Neil A, Piccardo, Pedro, Cheeseman, Michael T, Burdon, Tom, Hume, David A

“…We have produced -deficient rats by homologous recombination in embryonic stem cells. Consistent with the role of in macrophage differentiation, there was a…”
Get full text

Photosynthesis and photoprotection in mangroves under field conditions by CHEESEMAN3, J. M., HERENDEEN, L. B., CHEESEMAN, A. T., CLOUGH, B. F.

“…ABSTRACT Net CO2 exchange and in vivo chlorophyll fluorescence were studied in mangrove (Rhizophora stylosa) leaves at a field site in Western Australia, and…”
Get full text

Enrichment of adeno-associated virus serotype 5 full capsids by anion exchange chromatography with dual salt elution gradients by Lavoie, R Ashton, Zugates, Jeffrey T, Cheeseman, Andrew T, Teten, Matt A, Ramesh, Srivatsan, Freeman, Julia M, Swango, Summer, Fitzpatrick, Jeremy, Joshi, Amod, Hollers, Bradley, Debebe, Zufan, Lindgren, Tyler K, Kozak, Amber N, Kondeti, Vinay K, Bright, Mary K, Yearley, Eric J, Tracy, Alexander, Irwin, Jacob A, Guerrero, Michael

“…Adeno-associated virus-based gene therapies have demonstrated substantial therapeutic benefit for the treatment of genetic disorders. In manufacturing…”
Get full text

Correction: Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus by Pridans, Clare, Raper, Anna, Davis, Gemma M, Alves, Joana, Sauter, Kristin A, Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J, Clohisey, Sara, Bush, Stephen J, Rojo, Rocío, Lisowski, Zofia M, Wallace, Robert, Grabert, Kathleen, Upton, Kyle R, Tsai, Yi Ting, Brown, Deborah, Smith, Lee B, Summers, Kim M, Mabbott, Neil A, Piccardo, Pedro, Cheeseman, Michael T, Burdon, Tom, Hume, David A

Get full text

Myringotomy in the Junbo mouse model of chronic otitis media alleviates inflammation and cellular hypoxia by Bhutta, Mahmood F., Cheeseman, Michael T., Brown, Steve D. M.

“…Objectives/Hypothesis Ventilation of the chronically inflamed middle ear is a key outcome in functional middle ear surgery. Grommets eliminate middle ear…”
Get full text