Search Results - "Cheeseman, Jennifer"
-
1
CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire
Published in Blood (18-06-2015)“…Although cytomegalovirus (CMV) reactivation has long been implicated in posttransplant immune dysfunction, the molecular mechanisms that drive this phenomenon…”
Get full text
Journal Article -
2
The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study
Published in PLoS medicine (01-11-2014)“…Development of noninvasive molecular assays to improve disease diagnosis and patient monitoring is a critical need. In renal transplantation, acute rejection…”
Get full text
Journal Article -
3
Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection
Published in PloS one (05-08-2013)“…The mechanisms underlying latent-virus-mediated heterologous immunity, and subsequent transplant rejection, especially in the setting of T cell costimulation…”
Get full text
Journal Article -
4
Multicenter comparison of laboratory performance in cytomegalovirus and Epstein-Barr virus viral load testing using international standards
Published in Clinical transplantation (01-12-2014)“…Background Infections with cytomegalovirus (CMV) and Epstein–Barr virus (EBV) remain important in solid organ transplantation. Quantitative viral nucleic acid…”
Get full text
Journal Article -
5
Breed effect on early cytokine mRNA expression in spleen and cecum of chickens with and without Salmonella enteritidis infection
Published in Developmental & Comparative Immunology (2007)“…We examined mRNA expression of 11 genes: BAK, Bcl-x, Interferon [IFN]- γ, Interleukin [IL]-1 β, IL-6, IL-10, IL-12 α, IL-12 β, IL-18, CXCLi2 [IL-8/CAF], and a…”
Get full text
Journal Article -
6
Limiting the amount and duration of antigen exposure during priming increases memory T cell requirement for costimulation during recall
Published in The Journal of immunology (1950) (15-02-2011)“…Donor-reactive memory T cells (Tmem) can play an important role in mediating graft rejection after transplantation. Transplant recipients acquire…”
Get full text
Journal Article -
7
Expression of neural markers on bone marrow-derived canine mesenchymal stem cells
Published in American journal of veterinary research (01-11-2006)“…To evaluate cell surface markers of bone marrow-derived canine mesenchymal stem cells (MSCs) by use of flow cytometric analysis and determine whether canine…”
Get full text
Journal Article -
8
Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection
Published in Frontiers in medicine (01-11-2017)“…Despite potent immunosuppression, clinical and biopsy confirmed acute renal allograft rejection (AR) still occurs in 10-15% of recipients, ~30% of patients…”
Get full text
Journal Article -
9
Migration and differentiation of canine bone marrow stromal cells transplanted into the developing mouse brain
Published in Journal of Veterinary Medical Science (01-03-2010)“…To evaluate whether canine bone marrow stromal cells (BMSCs) can migrate and adopt neural phenotypes in the developing mouse brain we transplanted…”
Get full text
Journal Article -
10
Salmonella Enteritidis–Induced Alteration of Inflammatory CXCL Chemokine Messenger-RNA Expression and Histologic Changes in the Ceca of Infected Chicks
Published in Avian diseases (01-06-2008)“…To understand better the events in early avian host immune responses to Salmonella Enteritidis (SE), we examined messenger-RNA (mRNA) expression for eight…”
Get full text
Journal Article -
11
Nestin-positive spheres derived from canine bone marrow stromal cells generate cells with early neuronal and glial phenotypic characteristics
Published in In vitro cellular & developmental biology. Animal (01-05-2008)“…Bone marrow stromal cells (BMSCs) isolated from humans and rodents have been shown to generate neural cells under specific culture conditions and after…”
Get full text
Journal Article -
12
Reduced nitric oxide production and iNOS mRNA expression in IFN-γ-stimulated chicken macrophages transfected with iNOS siRNAs
Published in Veterinary immunology and immunopathology (15-10-2008)“…Utilizing RNA interference technology with siRNA in the HD11 macrophage cell line, we determined how the inhibition or knock-down of the iNOS (inducible nitric…”
Get full text
Journal Article -
13
effects of canine bone marrow stromal cells on neuritogenesis from dorsal root ganglion neurons in vitro
Published in Veterinary research communications (01-10-2009)“…The present in vitro study was designed to evaluate whether canine bone marrow stromal cells (BMSCs) promote neurite outgrowth from dorsal root ganglion (DRG)…”
Get full text
Journal Article -
14
The frequency, growth kinetics, and osteogenic/adipogenic differentiation properties of canine bone marrow stromal cells
Published in In vitro cellular & developmental biology. Animal (01-11-2008)“…Bone marrow stromal cells (BMSCs) have gained considerable attention as a potential source for cell transplantation therapies for a variety of diseases due to…”
Get full text
Journal Article -
15
In Vivo T Cell Costimulation Blockade with Abatacept for Acute Graft-versus-Host Disease Prevention: A First-in-Disease Trial
Published in Biology of blood and marrow transplantation (01-11-2013)“…Abstract We performed a first-in-disease trial of in vivo CD28:CD80/86 costimulation blockade with abatacept for acute graft-versus-host disease (aGVHD)…”
Get full text
Journal Article -
16
Measurement of myelin basic protein in the cerebrospinal fluid of dogs with degenerative myelopathy
Published in Veterinary clinical pathology (01-09-2007)“…Background: Analysis of cerebrospinal fluid (CSF) is part of a routine clinical workup in veterinary patients when neurologic disease is suspected. However,…”
Get full text
Journal Article -
17
Detection of oligoclonal bands in cerebrospinal fluid from German Shepherd dogs with degenerative myelopathy by isoelectric focusing and immunofixation
Published in Veterinary clinical pathology (01-06-2008)“…Background: Detection of intrathecal IgG synthesis is important in evaluating inflammatory diseases in the central nervous system. Isoelectric focusing (IEF)…”
Get full text
Journal Article -
18
Premature T Cell Senescence in Pediatric CKD
Published in Journal of the American Society of Nephrology (01-01-2017)“…An individual's immune function, susceptibility to infection, and response to immunosuppressive therapy are influenced in part by his/her T cell maturation…”
Get full text
Journal Article -
19
CD57+ CD4 T Cells Underlie Belatacept‐Resistant Allograft Rejection
Published in American journal of transplantation (01-04-2016)“…Belatacept is a B7‐specific fusion protein used to prevent allograft rejection by blocking T cell costimulation. Generally efficacious, it fails to prevent…”
Get full text
Journal Article -
20
Changes in Urinary Microbiome Populations Correlate in Kidney Transplants With Interstitial Fibrosis and Tubular Atrophy Documented in Early Surveillance Biopsies
Published in American journal of transplantation (01-03-2017)“…An unbalanced microbiome may lead to disease by creating aberrant immune responses. A recent association of cellular rejection with the development of…”
Get full text
Journal Article