Search Results - "Checkel, J.L"

IL-4 Plays a Pivotal Role in Regulating the Development of Th2 and Th17 Responses in the Airways by Kobayashi, T, Iijima, K, Checkel, J.L, Kita, H

“…IL-33 is produced by tissue cells, such as airway epithelial cells and endothelial cells, and has been implicated in the development of Th2-type inflammatory…”
Get full text

Airway Exposure to IL-33 Induces IL-5-dominant Th2-type Immune Responses to Inhaled Antigens and Asthma-like Pathology by Kobayashi, T, Iijima, K, Checkel, J.L, Kita, H

“…Airway challenge of these mice with OVA markedly increased bronchoalveolar lavage levels of Th2 cytokines and provoked airway eosinophilia, mucus…”
Get full text

Eosinophils Are Not Involved in the Sensitization Phase of Allergic Responses by Kobayashi, T, Iijima, K, Checkel, J.L, Kita, H

Get full text

Airway Exposure to Papain, a Cysteine Protease, Induces Allergic Inflammation by Karakelides, M, Iijima, K, Checkel, J.L, Kobayashi, T, Kita, H

“…The effects of papain were abolished by heat-inactivation or by pretreatment with a cysteine protease inhibitor, E64, suggesting that protease activity is…”
Get full text

Allergen-specific IgE, IgG, and Th2-type Cytokine Responses are Effectively Downregulated by Immunotherapy with the Novel Dendritic Cell (DC)-Stimulating Antibody, B7-DCXAb by Kita, H, Checkel, J.L, Iijima, K, Radhakrishnan, S, Van Keulen, V.P, Mcclimon, B.J, Kobayashi, T, Plager, D.A, Pease, L.R

“…Mice were sensitized by intraperitoneal injection of OVA or house dust mite (HDM) antigens plus alum and then treated by intravenous B7-DCXAb injection plus…”
Get full text

Major Basic Protein Homolog (MBP2): A Specific Human Eosinophil Marker by Plager, D.A., Loegering, D.A., Checkel, J.L., Tang, J., Kephart, G.M., Caffes, P.L., Adolphson, C.R., Ohnuki, L.E., Gleich, G.J.

“…Specific monoclonal antibodies for MBP2 were selected using slot blot analyses and employed in a two-site immunoassay, Western blotting, and immunofluorescence…”
Get full text

Eosinophil-derived neurotoxin and human liver ribonuclease. Identity of structure and linkage of neurotoxicity to nuclease activity by Sorrentino, S, Glitz, D G, Hamann, K J, Loegering, D A, Checkel, J L, Gleich, G J

“…Eosinophil-derived neurotoxin (EDN) and human liver RNase were found to be indistinguishable from each other but distinct from the pancreatic ribonucleases in…”
Get full text

Analysis of pregnancy-associated major basic protein levels throughout gestation by Wagner, J M, Bartemes, K, Vernof, K K, Dunnette, S, Offord, K P, Checkel, J L, Gleich, G J

“…Previous studies have shown that MBP levels rise before labour and have suggested the use of pMBP levels as a predictor of labour. We hypothesize that pMBP…”
Get more information